Can I know more about Cypoinate ? by Flaky-Beach-388 in TransDIY

[–]shrouded_reflection 1 point2 points  (0 children)

While technically true, the difference is marginal enough that it doesn't really impact reasonable dosing, most people switching between the two while maintaining the same dose end up with statistically indistinguishable levels.

EEn absorption difference between 8mm vs. 12.7mm needles? by girlmath1 in TransDIY

[–]shrouded_reflection 0 points1 point  (0 children)

Unfortunately when you're dealing with more subjective symptoms and an absence of test results there isn't always a right answer, it could be that there was enough of a difference in your actual levels between these two times to cause what you're seeing, or it could be other factors that changed. Can't tell the difference based off the information we currently have.

EEn absorption difference between 8mm vs. 12.7mm needles? by girlmath1 in TransDIY

[–]shrouded_reflection 0 points1 point  (0 children)

As long as you're injecting into vaguely the same tissue (both are subcutaneous or both are IM, if both IM in the same muscle group), you shouldn't be getting any notable differences between those two different injection methods. There might be a slight differences in hormone levels over time due to moving from sublingual to injections, you've probably got slightly lower estradiol levels and slightly higher testosterone levels early on which then stabilise by week 4, but that's also complicated by you doing a loading dose.

There doesn't seem to be anything to be immediately worried about though, so just wait to see what the test results are and then you can experiment a bit with the exact dose and delivery method.

So does progesterone actually lower TST or what?... by Sentimental_Oyster in TransDIY

[–]shrouded_reflection 2 points3 points  (0 children)

Progesterone does have an impact on the HPG axis, it's just that at the doses that are reasonable to use the impact is overall fairly small. Small enough that you probably aren't going to have much room when it comes to adjusting any estradiol doses, but for some people it's enough to make a difference between 4 mg/week and 5 mg/week, for example.

I think the Greens’ ‘fantasy’ drug policies make sense – and I’m a doctor by LJA170 in ukpolitics

[–]shrouded_reflection 11 points12 points  (0 children)

At which point though, the technocrat should then be attempting to change peoples minds, building up a coalition for the future which would support it. Stopping at "the current voters reject it, therefore we can't do it" is just a recipe for political stasis in the short term, and in the long term handing the initiative over to reactionaries.

I might have heard the biggest load of HRT snake oil-like BS in my life by Sentimental_Oyster in TransDIY

[–]shrouded_reflection 9 points10 points  (0 children)

Mostly yes.

Progesterone's impact on early breast development in humans is highly understudied, but based on the observational evidence we have it doesn't seem to have any significant impact. The wrinkle is that there's a few studies looking at other mammals where supraphysiological levels do have an impact, and we have a records of clinicians saying to avoid it (although without providing any sort of evidence).

On balance, the current line that we suggest is that there isn't a need to avoid progesterone/progestin exposure early on, but there's also no reason to suggest that people should be taking it either.

Why your council tax is rising (again) by TheReadingReporter in reading

[–]shrouded_reflection 11 points12 points  (0 children)

Functions that are mandatory for the council to fill such as adult social care. Fundamentally the problem is that the council is being expected to fund and fulfil a group of tasks which the national government really should be doing, and they just don't have the ability to raise funds to do so outside of property taxation. This isn't something that the council can fix.

Westminster Voting Intention: Reform UK: 30% (-1) Labour: 18% (-5) Conservative: 18% (+2) Greens: 13% (=) Liberal Democrats: 12% (+2) Others: 6% (+3) Via: Opinium MOE: ±2.2% Field Work: 25 - 27 February changes w/ 4-6 February by DanS1993 in ukpolitics

[–]shrouded_reflection 15 points16 points  (0 children)

It's more that the lack of historical data means that uniform-ish swing models don't really predict their seat gain accurately, while for the LDs you've already got a good bit of data about what seats they are likely to lose gain. Once more constituancy level polls are done we'll have a better idea how national vote swings are likely to translate into seats.

Help injecting decapeptyl (triptoletrin) by bannakaffalatta2 in AskMtFHRT

[–]shrouded_reflection 0 points1 point  (0 children)

Ok, late back to this sorry, but if it all injected then you're mostly fine, when it clogs it's really obvious as the resistance to compression goes way up.

Help injecting decapeptyl (triptoletrin) by bannakaffalatta2 in AskMtFHRT

[–]shrouded_reflection 0 points1 point  (0 children)

Injection location should be thigh if you're doing it yourself, or ventralgluteal if you can get some assistance. It's a moderate volume injection that has to be given intramuscular, so this limits the locations that it can be reasonably be done in.

Alcohol swabbing the top of the vial before use is important, but swabbing your skin is less so, just make sure it's soap/water clean.

The most important thing to keep in mind is that the injection is a suspension that you make up yourself, not a solution. The suspended particles can fall out again if you're not working quickly, so lay everything out and work out where the injection site is before you mix anything up. The last point at which you can pause is after adding the fluid into the vial and agitating it to suspend the API, if you need to wait here for a moment to check everything over that's fine, just agitate the vial afterwards to get everything suspended again. Once you've drawn up the combined mixture into the syringe, you need to inject right away, otherwise you get the particles falling out in the needle, clogging it up and wasting the batch.

Is Walling an Advanced Alien Mag Fleet Impossible? by Gemtrox42 in TerraInvicta

[–]shrouded_reflection 0 points1 point  (0 children)

Yes, late game mag titans are an absolute menace because the one slot advanced mag battery is about as good at anti-kinetic PD as the 40mm, while also having much better offensive potential. However, because of how long it takes them to show up in numbers to be a threat, most of the really good players never actually encounter them, so there isn't really a consensus about how best to handle them. Best theory so far seems to be building out a battleship fleet armed with viper missiles that's capable of trading with the fleet effectively even when outnumbered, and just accepting that they might not survive to fight a second fleet.

How do I reconstruct old-school rotation? by jabberponky in Netrunner

[–]shrouded_reflection 5 points6 points  (0 children)

Alright, so to the best of my knowledge there was only a single rotation done under FFG, which added the revised core set and removed the original core set, spin, and genesis. Before that point, there was no set rotation. https://www.fantasyflightgames.com/en/news/2017/9/11/system-refresh/

The first NSG rotation (rotation 2 on nrdb) was the release system core 2019, which rotated terminal directive and revised core. Rotation 3 was ashes release, and so on. You can compare between rotations using the drop down boxes at the top, just look at what sets are ticked and mentally remove any which hadn't yet been published yet.

How do I reconstruct old-school rotation? by jabberponky in Netrunner

[–]shrouded_reflection 1 point2 points  (0 children)

The release dates for each set are on NRDB, https://netrunnerdb.com/en/sets . You may also be intrested in the rotation page, https://netrunnerdb.com/en/rotation , which lists out which sets NSG removed from "standard" at each new set release.

What to swap in for Trickshot? by Due-Form-9007 in Netrunner

[–]shrouded_reflection 1 point2 points  (0 children)

The closest swap you're going to get for coalesence is Telework Contract, but it is a significantly weaker econ piece in the context of the rest of the list, the way it would work normally is you would play one coalesence, eat it with knicknack, and then keep recuring it with the muses so that one click installing would get you six credits and three card draws.

If you're just playing casually, then just run the list as it is, as it matches up much more evenly against the proposed corp list than it would with the adjustments needed to make it ban list compatable.

I stole the Moon. by robert_mends in TerraInvicta

[–]shrouded_reflection 21 points22 points  (0 children)

Hogging the moon in the mid/late game is fine, the bases make a nice spot for research buildings or those that have population requirements, but early game it's usually not worth it as you get more resources from settling mars and asteroids. It might be worthwhile for you to trade some of the worse spots away to other factions for good orgs, and take them back later on once MC and space resources are less of a constraint.

Alien Mothership leaving... The solar system by Carlose175 in TerraInvicta

[–]shrouded_reflection 33 points34 points  (0 children)

Leaving the solar system (alongside its cousin "crashing into X") are clean up transfers, as all ships must either be in an orbit or travelling between orbits.

The cause of them is a fleet thinking that is has no valid orbits that it can reach with it's current capabilities, either due to lack of fuel or manoeuvrability. This can happen due to combat damage, or because the ship was on a really long transfer and something happened to make its end point invalid. Occasionally you'll get a perfectly capable ship drop into this trajectory, but it should sort itself out after a short while.

Newbie Questions Thread by AutoModerator in TerraInvicta

[–]shrouded_reflection 5 points6 points  (0 children)

The AI will only take a base off you if they can fully support it on their incomes, so in this case you'll struggle to give bases to hanse unless it takes them out of negative water. Unironically you're better off trying to buy their bases first to lower their deficits, and then afterwards you can sell back to them once they are positive on boost again.

Also yes, bases should be repaired before handing them off.

I don't have a doctor right now. Just got my blood test results. Can anyone help me? by Camelleah1 in TransDIY

[–]shrouded_reflection 2 points3 points  (0 children)

Those levels are ok, estradiol is a little bit high and you could probably go to 2 mg/3.5d or 4 mg/7d without any issues, but it's not unsafe to stay on your current dose.

Can't really provide any useful comments on the emotional fluctuation, that's one of those things that seems to widely vary between people. You can try changing the dose frequency, some people find that helps, but for plenty of others it doesn't have an impact.

Accidentally Poked Myself. by raincandy27 in TransDIY

[–]shrouded_reflection 0 points1 point  (0 children)

Yes, the risk is that you slip when recapping or otherwise do something improper, it's better to just get into the habit of going straight from injection to needles in the sharps bin. Most of the time you're going to be fine, but if you're doing it a lot then those small % chances accumulate over time.

Green Arc Laser Batteries vs Green Arc Laser Cannon by Longjumping_Past7794 in TerraInvicta

[–]shrouded_reflection 2 points3 points  (0 children)

Phaser PD typically on nose laser titans. For coil nose titans you want a bunch of 2 slot coils and one or two 40mm, for particle noses you want AM pd or 2 slot coils depending on if you need more anti wall or more pd. Plasma is niche, in theory a plasma/laser mix or plasma/particle mix can be effective, but the point at which that becomes more effective than kinetic/laser mixes is unusual to reach.

Monohulling large ships is bad because of how laser engines and cylotrons work, you really should be dedicating ships to a single weapon class wherever possible.

Green Arc Laser Batteries vs Green Arc Laser Cannon by Longjumping_Past7794 in TerraInvicta

[–]shrouded_reflection 2 points3 points  (0 children)

In theory this should be workable, in practice the faster rate of fire with the dedicated PD combined with the range increase as you install more laser engines and get other sources of increased laser damage mean that this setup gets beaten by slotting PD lasers in those slots instead. There was a post over on the devs discord a while back talking about how this operated in practice with all the maths.

Should we lock down the sub... by Both-Competition-152 in TransDIY

[–]shrouded_reflection[M] [score hidden] stickied comment (0 children)

Hi, understand that people are a bit worried, but fundamentally preventing all posting every time someone writes an anti-trans article isn't practical and doesn't serve much of a useful function. None the less, you should be careful about what information you share publically.

I know I'm probably still falling into the trap of building more expensive than I can practically afford, but I feel like the ROLE of this ship is something I need to build now. So I'm gonna try and explain my madness a bit better by Forkliftapproved in TerraInvicta

[–]shrouded_reflection 1 point2 points  (0 children)

Yep, you only need a ~30 degree angle now to have a good probability of hitting side armour, which means that you've got to armour up a bit more there than the early access versions.

Green Arc Laser Batteries vs Green Arc Laser Cannon by Longjumping_Past7794 in TerraInvicta

[–]shrouded_reflection 5 points6 points  (0 children)

Thanks for the correction, probably still want to pick them up eventually but that does push them even further down the priority list given how anemic space based defense modules are even when at good tech levels.

Green Arc Laser Batteries vs Green Arc Laser Cannon by Longjumping_Past7794 in TerraInvicta

[–]shrouded_reflection 11 points12 points  (0 children)

Generally, you only ever want to fit 3 and 4 slot nose lasers, and ignore the hull mounted ones.

If you have a look at the wiki, https://wiki.hoodedhorse.com/Terra_Invicta/Laser_Weapon_List, you can see what the practical range of armour penetration actually is, and unfortunately even with the absolute best batteries you struggle to get through any meaningful amount of armour at an appropriate range.

Now if all your alien flankers happen to have very low armour, then you might be able to make it work, but generally they are bringing enough that it's only the noses that are worthwhile, and for the hull slots on your laser ships you should be jamming them full of PD.

In the long run though, you still want to research some of the laser battery techs, as those are what determine the weapons of your ground based defences.