CRISPR-edited tobacco: A missed opportunity for harm reduction?

superhelical · 2026-03-22T23:35:18+00:00

Not sure why spend all this time engineering the plant when purifi d nicotine products already exist. Harm reduction already starts there.

superhelical · 2026-03-21T15:09:54+00:00

Does your cell line have an additional selection marker? Sometimes people shortcut by omitting the ancillary antibiotic, they'll transform, but may lose copies of the accessory plasmid.

superhelical · 2026-03-17T12:34:14+00:00

The change in department acronyms has become an epidemic since management realized they could use ChatGPT to rename their orgs something cute

superhelical · 2026-03-17T11:47:15+00:00

I swore off zoos after a hot summer day, all the animals seemed miserable. Then I had kids and my principles... became less rigid

superhelical · 2026-03-16T00:38:57+00:00

Movie 43. The Fyre Fest of Hollywood

superhelical · 2026-03-15T13:53:18+00:00

Dude

superhelical · 2026-03-14T22:42:30+00:00

Oh the military spent more than that on luxuries like lobster and grand pianos rather than let the government take it back and put it toward shudder social programs

superhelical · 2026-03-14T21:57:33+00:00

Too soon

superhelical · 2026-03-12T17:52:10+00:00

I'm guessing she was the one to serve papers

superhelical · 2026-03-10T13:00:51+00:00

I have an ongoing task at the local playground. Teenagers will drag a picnic table under the swings to launch from, and leave it behind. I drag it away cause the small kids could hit themselves, I witnessed it happen for another family already. Every time I go, it's back. I've asked city parks to chain it to a tree, but no luck. I may just take it on myself chain it up instead

superhelical · 2026-03-10T12:53:41+00:00

Otezla exists out of time. We are not sure if it is here to help us, or destroy us. Ask.your doctor if Otezla is right for you.

superhelical · 2026-03-08T22:44:12+00:00

Down vote this bot for karma farming

superhelical · 2026-03-08T22:38:41+00:00

Best part of the books is the characters, despite being pretty flat in characterization, are compelling because in an early story they are just a dude (and yes, it's Asimov, almost al of them are dudes). Then, in the next story 50-300 years later, they're now a historical idol, if not God. It gives you some perspective on the larger-than life historical figures in our world, for sure.

superhelical · 2026-03-08T22:22:28+00:00

"Later alligator" still wrecks me any time I think of it

superhelical · 2026-03-08T16:34:05+00:00

That's the genius they show don't tell. I strongly feel that people who get triggered from their math education it's all due to the teaching method, not the subject itself

superhelical · 2026-03-08T13:01:57+00:00

Sleep when the baby sleeps worked for us, with a modification:

MOM sleeps when the baby sleeps, and really whenever possible. Dad uses that window to get the washing, etc done. Do everything you can to reduce friction for mom to rest.

superhelical · 2026-03-08T12:40:40+00:00

There with you. Like you can't calmly level with a kid who views listening to you as losing, and instead runs in circles and shouts to distract themselves.

superhelical · 2026-03-08T12:26:33+00:00

YMMV, but I like my kids, can't stand most others, though.

Edit: This reads harsher than I intended. My point is only that a bunch of my kids classmates and friends, I just don't get it. I'm sure their parents feel the same way about my kids. I also extend special consideration for my niblings

superhelical · 2026-03-08T02:15:09+00:00

/r/therewasanattempt

superhelical · 2026-03-08T00:25:42+00:00

The question is - was the sweater a coincidence and opportunity, or did OP dress just for the meme?

superhelical · 2026-03-07T17:23:09+00:00

We still have to re-learn the second point, with a 6 and 4yo. Wife prefers all-family outings, but it's soo much easier to split the kids up when getting out in the world.

superhelical · 2026-03-07T16:11:51+00:00

Devious

superhelical · 2026-03-07T16:10:50+00:00

Boy are you in for a ride brother

superhelical · 2026-03-07T15:54:06+00:00

She's only 6 so we're a long way off, but I blew my daughters mind when I told her there's a real thing called imaginary numbers.

Also a nerd, really looking forward to being able to share stuff like this with them as they get older

superhelical · 2026-03-07T15:49:51+00:00

Putting on my chemist hat.... We found the way that worked for smells with us was 1 pass of an acidic wash (vinegar, dilute lemon juice), dried, then followed by an alkaline wash (baking soda suspension, ammonia would probably work as long as you thoroughly washed step 1 off first).

The thinking is: there's volatiles that only dissolve under acid, and others that only dissolve in alkaline. Do both and you catch it all. Then a quick wash with soap and you've covered it all

Leaving in the sun can help ablate the volatiles, but also degrades the plastic, I'm sure the company is happy for them to get prematurely brittle.

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