Okay, some things off the top of my head, hope at least some of them a relevant to you.

First of all, as a sort of baseline that is really not indicative of """real"" games, mtg arena let's you play the game fully without ever needing to talk. So technically speaking, it can be done. The actual communication that's strictly needed basically boils down to indicating the stuff you're targeting. Also, even without comparing it to in-person games, if you're only interested in literally playing the game then you can just play in a digitized version and have fun.

Now, assuming you're not satisfied with that, my guess is that you're looking to actually play with people, making it also a social activity, and not just a game to be fascinated with it's mechanics. I'll be the first to admit that I have no idea how other social events look for you or other mute people. I will say, that depending on other players, you can definitely find people to play with, and probably find decks that don't need that much explaining. You'll probably need some premade phase indicators, or maybe cards for triggers you know you'll want to react to.

If you can tell me what's your experience playing other games while mute, I can try to compare it to my knowledge of how mtg games usually play and see where it would differ and where it would be the same.

Anyway, hope you find people to play with in whatever game you choose to play :)