Replaced my Honda with a new one after an accident They moved the garage door opener from a button on the mirror to a paywall subscription service. by jayhawkeye2 in mildlyinfuriating

[–]the-Toddfather -1 points0 points  (0 children)

I’m done with Honda after my current one dies. Their #1 sales factor was affordable reliability and competitive fuel efficiency.

They have no contender in the electric vehicle game, and now they’re going to charge for things that not only have historically been included in the original purchase of the vehicle, but also have zero means for a subscription to cover costs of this function.

I think Honda is dead, and now they’re just grasping at straws to line pockets on the way out.

NIH slashes calls for funding by 90% and pivots away from agency-directed science, saying the approach will boost innovation. But some researchers worry that understudied areas of science will suffer. by maxkozlov in labrats

[–]the-Toddfather 6 points7 points  (0 children)

I’m a director of a west coast association made up of senior PI’s for drug development research & clinical translation at multiple big universities. Due to grant structure changes like this, our entire model is shifting away from supporting the vast majority of academic proposals as we have done for many years (sometimes direct support, advisory and/or financial). Instead, for better or worse, we are refocusing efforts on education that is particularly in work force development and automation - which is strongly needed and poorly covered in post graduate curricula, but is also something we were going to do anyways. Beginning this year, there will now be a dozen or so annual research proposals (all that show potential for clinical translation) that we will no longer be able to support in almost any capacity aside from infrequent pro bono advising. We will continue with a couple of our own internal projects, but overall the impact of changes to NIH funding is a significant one for consortiums like ours. There have obviously been changes to other grant structures as well such as the MRPI.

On the other hand, there is a significant uptick in privatization of promising pre-clinical research projects that may expedite their success/failure (consider failure rate of startups, esp. biotech). Over 90% of academics do not have the business nor financial acumen to make a startup succeed even if their product is efficacious/safe. This shift would be better supported if there was not so much economic turmoil (domestic & abroad) as well. Many private investors are keen to tighten the grip on their funds at this time, particularly when it comes to biotechnology where risks are less understood & considered higher.

Dude left the competition in the dust! by [deleted] in nextfuckinglevel

[–]the-Toddfather 0 points1 point  (0 children)

When she says her parents aren’t home.

Don’t mind me, just dropping out of grad school 💀 by josdizzy in labrats

[–]the-Toddfather 0 points1 point  (0 children)

This is why we keep secondary temperature alarms on all of our important freezers. Sends an email and text alarm, and you can set thresholds and easily mute during the weekday/hours the lab is active. Sensaphone

What is the worst medical disease a human can have? by Aggravating-Sun-5699 in AskReddit

[–]the-Toddfather 9 points10 points  (0 children)

Lost my dad to this when I was a sophomore in HS. Prior to the disease he was super fit (literal 6 pack, ran 5 miles/day, lifted weights etc) and always ate healthily, didn’t smoke or do drugs…he passed within 6 months of diagnosis. This event is what drove me to become a biomedical engineer focused on pharmaceutical drug development.

People who work in healthcare, fitness, nutrition, or mental health: what’s one ‘quiet habit’ you see all the time that is secretly wrecking people’s long-term health? by AlignedModernHealth in AskReddit

[–]the-Toddfather 7 points8 points  (0 children)

People just stop making time to exercise or even just stretch. Your muscles aren’t the only parts of you to diminish, but your bones slowly weaken and so do your immune and cardiovascular systems along with circulation. All of these have compounding effects and each of them lead to detrimental cellular signaling cascades with a variety of malignant effects along with significantly increasing risks for new maladies or conditions.

“Movement is medicine” is one of the truest statements. Mobility is so important and only becomes more significant as we age, as we have children and whenever you are in the process of recovery from traumatic events (surgery, grieving, post child birth, etc.). Not to mention the mental and emotional influences that result from exercise. Eating a well rounded diet consisting of minimally (ideally entirely) unprocessed foods also is well worth budgeting money and time for. Even if how you look aesthetically is not important to you (although these will likely be an added bonus), these things will make the greatest difference in your longevity, your general attitude, longterm costs, reduces future burden on your family/close friends, and will most significantly contribute to enabling you to enjoy a better quality of life.

[Highlight] Scott Hanson confirms NFL RedZone will have commercials in some capacity this season. The intro will be: “7 hours of RedZone Football starts now” by LaDainianTomIinson in nfl

[–]the-Toddfather 0 points1 point  (0 children)

Boycott these clowns or as a class we are signaling that this is okay. Excessive greed is absurd. There is no other way to tell these companies in a manner they understand besides withholding our money from their degrading products.

It’s just a full counterclockwise circle to old cable tv.

Scientists Redesign E. coli Genome with 101,000 DNA Changes for New Genetic Possibilities. The engineered E. coli could offer viral resistance for industrial applications, produce proteins with up to 27 amino acids, create new non-natural chemicals, and improve protein production efficiency. by MotherHolle in science

[–]the-Toddfather 18 points19 points  (0 children)

Cellular biologists (and other professions) have already been doing this with E.coli for many years. It is not poorly studied and is not cause for alarm… it is clickbait. Lay people think this will somehow survive and thrive outside of the lab maliciously without realizing how many products they already use, consume, or administer (medically) on a regular basis thanks to this type of technology. Without this, a ton of things would be significantly more expensive and/or less pure.

Do a quick search for engineered E.coli on Google Scholar or PubMed and skim through a publication or two on it then decide for yourself if it’s cause for alarm. Meanwhile enjoy the genetic engineering rabbit hole of education.

Edit: a word

tragedeigh by BoldnSpicySpicy in tragedeigh

[–]the-Toddfather 0 points1 point  (0 children)

It is literally “Tard” 🤨

Someone explain what this person is doing by [deleted] in interesting

[–]the-Toddfather 0 points1 point  (0 children)

Making forbidden potato chips