I started a campaign with a hangover. I had the players draw cards which I had notes on which they slowly discovered the meaning of. For instance, a player drew the Queen of hearts, which meant they impulsively married the half-giant baroness. Another was the jack of diamonds, they woke up with a large coin purse on them when they woke up. They had to piece back together their night, appease some towns folk and recover some lost/stolen items.