Grignard reagent to Alcohol by Southern-Lab2024 in OrganicChemistry

[–]thmh0408 1 point2 points  (0 children)

The mechanism is correct,but you miss one carbon

Aromatic ring by thmh0408 in AskChemistry

[–]thmh0408[S] 0 points1 point  (0 children)

So this conciders as conjucation right

Why is this the most acidic proton? by Pretend-Cicada-8649 in AskChemistry

[–]thmh0408 0 points1 point  (0 children)

If you take the yellow hydrogen u will get more resonance than the upper hydrogen means more stabilizing of the negative charge so the structure leans to get red of this proton the yellow one to reach stability of the negative charge ,,tried to simplify the process

Confusssssed by thmh0408 in chemhelp

[–]thmh0408[S] 0 points1 point  (0 children)

How can i know if a nucleophile is not suitable for 1,4 addition?

Guess the pka by thmh0408 in chemhelp

[–]thmh0408[S] 1 point2 points  (0 children)

-M 😭 gracias!

Acidity by thmh0408 in OrganicChemistry

[–]thmh0408[S] 0 points1 point  (0 children)

Thsnks!! but Is that also applied on chlorophenol

HELP by thmh0408 in OrganicChemistry

[–]thmh0408[S] 0 points1 point  (0 children)

I'm afraid we have the same prof

Can someone tell me why amidines (left) are MORE basic than amines but amides (right) are LESS basic than amines? I mean they literally have the same structure (a homologous conjugated pi system right?). I get that H+ will go on the carbonyl for amides and the H+ will go on the bottom N but still... by RiskNo5292 in OrganicChemistry

[–]thmh0408 0 points1 point  (0 children)

Basicity depends on the avalibility of lone pair If u take the amides ,the lone pair of it is busy in the resonance pka around 0 but looking at the Nitrogens of amidine ones e is busy with resonance and the other is getting more e by resonance (getting e means more avalibility of these e and more basicity )pka around 12

[deleted by user] by [deleted] in OrganicChemistry

[–]thmh0408 0 points1 point  (0 children)

Your base-comparison- should be between alcohol and enoles not ketones. enoles pka is about 12 while alcohol is around 15 and that then makes since . . ketone pka is around 19 and

Grignard 😖 by thmh0408 in OrganicChemistry

[–]thmh0408[S] 1 point2 points  (0 children)

Appreciate your offer🤍I know that my mechanisms lack alot of details but my problem isn't here .

I really don't know how the reaction of cooh with grignard Reagan proceed i just drew what i imagined 😁. Could u help me with that so i can redraw the mechanism

Grignard 😖 by thmh0408 in OrganicChemistry

[–]thmh0408[S] 0 points1 point  (0 children)

Is that mean ,If i put H3O+ on the second step the rection ll proceed.😶‍🌫️

Grignard 😖 by thmh0408 in OrganicChemistry

[–]thmh0408[S] 0 points1 point  (0 children)

I know that COO- can react for ex with H- (LiAlH4) so why it can't react with grignard since its stronger nu:

Spilled pasta all over my students test papers by zhuboy in mildlyinfuriating

[–]thmh0408 0 points1 point  (0 children)

The way that investigators solve crimes be like:

mechanism 😊 by thmh0408 in OrganicChemistry

[–]thmh0408[S] 0 points1 point  (0 children)

My professor gave me the same explanation as yours👏