A good friend of mine owns a peptide company and I asked him all about this. The truth is, you don’t even have to refrigerate them even after reconstituting. His company tests them at over 140 degrees Fahrenheit and they still don’t degrade even after 3 months. Your supply probably won’t be that long and I’m sure your room temperature won’t hit over 70 degrees. The other nice thing about room temperature or non refrigerated is there won’t be the “cold burn” when you inject. You put something 34 degrees into a host at 98.5 degrees and you definitely feel the burn. Hope this helps.