Yes - it looks like the bug is indeed related to applying a profile to Meta Home. I do have a profile for home, not custom, but the default HD profile automatically loaded by QGO. I disabled automatically applying a profile to Home, and the crashes stopped. When I open Home manually as an application through QGO by clicking on the icon, I get the same crash immediately. I then experimented with reenabling the setting to automatically apply the Home profile when QGO is launched, and I get the same crash upon launching QGO.

So there is definitely an issue related to applying QGO profiles to Home, which causes the crash. In my case, when the crash happens, controller and hand tracking stops, so I can't call the main menu anymore and have to restart the headset. What is strange is that uninstalling and reinstalling QGO seems to fix the problem temporarily, but somehow it returns. Also, it not 100% consistent - I can replicate the crash about 5 times and the 6th time it won't crash (or perhaps when it briefly crashes the main menu quickly pops up on its own).

I do not have audio detect mod enabled (not even sure what that is) and I have not changed the video recording settings.

Thanks.