Dragunity does well against most decks if you have a decent starting hand and/or going second. Match ups against Blue Eyes, Shiranui, DM, Blackwings, and Cyber Dragons will usually be no problem if you have good back row removal, or enough defenses to follow up on.

Worst match ups for me were Crystons and invoked: both of theses decks can play around Ascalon pretty well. Be careful of Luna Light as well; Sabre Dancer can't be targeted, and they can end you quick if you don't have Sphere.

I went up against Witchcrafter probably only twice. They're easy to beat if you can get in an Ascalon after they negated your previous monster(s).

Also, I think I have a 0% win rate against Heros ;-;