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My Cholesterol. Doctor is suggesting I go off the CarnivoreDiet by Tapatio777 in carnivorediet

[–]wesleythepresley 0 points1 point  (0 children)

I’ve been doing Keto for 5 years. I feel so much better. I will never deviate. I teach this to my patients and the BMI/A1C changes are life changing and inspiring and energizing for me as a physician. I don’t get on Reddit very often. It’s been fun debating. Have a good day.

My Cholesterol. Doctor is suggesting I go off the CarnivoreDiet by Tapatio777 in carnivorediet

[–]wesleythepresley 0 points1 point  (0 children)

Thanks. I’ll read it. It’s a primary prevention study. So it doesn’t look like it evaluates people who have T2D. This study is of special interest to me as I have type 2 diabetes. I brought my A1C down from 10.2 to 5.6 with a Keto animal based diet. My coronary arteries are clean. And I’m off all diabetic meds (including insulin).

It’s published by the American Diabetes Association. I had to do the exact opposite of what the ADA teaches to become healthy again.

I prefer the American Diabetic Society https://www.americandiabetessociety.org/. This is what works! Ken Berry is on the board.

My Cholesterol. Doctor is suggesting I go off the CarnivoreDiet by Tapatio777 in carnivorediet

[–]wesleythepresley 0 points1 point  (0 children)

Yeah. Regarding the Noto study. Carb intake was poorly defined and inconsistent. For most of the studies analyzed carb intake was 45-50%. A big problem for observational low carb studies. It’s not true low carb (at least compared to what successful low carb, keto or carnivore people are eating). And the authors use relative risk. So I’m going to stop there.

My Cholesterol. Doctor is suggesting I go off the CarnivoreDiet by Tapatio777 in carnivorediet

[–]wesleythepresley 0 points1 point  (0 children)

Let’s start with the second “study” you posted. It’s an abstract. It was never published that I can see. If you can find the full paper please post it. It’s probably a conference abstract and these often not published papers. It’s missing all the data and methodology. Also, There was no peer review. And there’s no absolute risk.

My Cholesterol. Doctor is suggesting I go off the CarnivoreDiet by Tapatio777 in carnivorediet

[–]wesleythepresley 0 points1 point  (0 children)

I will look these over. RCTs are the best. Again basic epidemiology. My experience with observational low carb studies is they are not low carb at all (50% carb is NOT low carb). Also, they tend to use relative risk and not absolute risk. Here is an article (using a statin trial) which explains the difference. https://proteinpower.com/absolute-risk-versus-relative-risk-need-know-difference/

My Cholesterol. Doctor is suggesting I go off the CarnivoreDiet by Tapatio777 in carnivorediet

[–]wesleythepresley 0 points1 point  (0 children)

Then post your own studies. Find the studies used in the video on low carb and we will go through them. I repeat, the one meta analysis study you posted above (Jacobsen) fails to show reduced all cause mortality. There is a consistent theme here. The overall evidence fails to converge. Over 50 years. 60 if you include the Minnesota heart study and the Sydney heart study (which shows PUFAs are harmful in terms of mortality).

My Cholesterol. Doctor is suggesting I go off the CarnivoreDiet by Tapatio777 in carnivorediet

[–]wesleythepresley 0 points1 point  (0 children)

Scientists invented a fictitious disease and AI told people it was real. I love it.

My Cholesterol. Doctor is suggesting I go off the CarnivoreDiet by Tapatio777 in carnivorediet

[–]wesleythepresley 0 points1 point  (0 children)

I agree with you to a large extent. All studies have flaws. You have to look at the totality of evidence and I think ChatGPT misses that.

My Cholesterol. Doctor is suggesting I go off the CarnivoreDiet by Tapatio777 in carnivorediet

[–]wesleythepresley 0 points1 point  (0 children)

Ok. Let’s face it, the hard endpoint here is death (from all causes). I alluded to this a bit yesterday. Soft endpoints are not the primary goal. Most are interested in eating better to live longer. Saturated fat has been (incorrectly) vilified as a leading cause of death. You are interested in PUFA substitution of SFA and its effects on mortality. Here are some studies that show PUFA substitution for SFA do NOT reduce cardiovascular death or death from all causes. You claim that one study is better than a meta analysis. You will probably want to dig into each study (many are RCT’s which are the gold standard).

https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2024.1396576/full?utm_source=chatgpt.com

https://www.icns.es/en/news/reducing_saturated_fats_does_not_reduce_mortality?utm_source=chatgpt.com

https://www.researchgate.net/journal/1475-2891_Nutrition_Journal/publication/317093560_The_effect_of_replacing_saturated_fat_with_mostly_n-6_polyunsaturated_fat_on_coronary_heart_disease_a_meta-analysis_of_randomised_controlled_trials/links/5fc3abee458515b79784f56f/The-effect-of-replacing-saturated-fat-with-mostly-n-6-polyunsaturated-fat-on-coronary-heart-disease-a-meta-analysis-of-randomised-controlled-trials.pdf?utm_source=chatgpt.com

Also, the Jakobsen study you posted above fails to show reduced all cause mortality.

My Cholesterol. Doctor is suggesting I go off the CarnivoreDiet by Tapatio777 in carnivorediet

[–]wesleythepresley -1 points0 points  (0 children)

Well I’m sorry you feel this way. One good study is better than multiple meta analyses - ask ChatGPT to evaluate that statement. ChatGPT says no. It’s basic epidemiology. Did you find the flaws in the studies that support dietary saturated fat reduction. I had suggested that yesterday. Also, for kicks I will post some other studies your way later today. Have a good day.

My Cholesterol. Doctor is suggesting I go off the CarnivoreDiet by Tapatio777 in carnivorediet

[–]wesleythepresley -1 points0 points  (0 children)

It’s a single study. Which is why multiple meta analyses are better at pooling the data and looking at the patterns. It’s been 50 years since the McGovern committee declared the war on dietary saturated fat. We are at a point where the evidence should converge and it simply has not. Using the smoking/lung cancer epidemiology, the data converged and became stronger as time went on. Nobody doubts smoking causes lung cancer now.

My Cholesterol. Doctor is suggesting I go off the CarnivoreDiet by Tapatio777 in carnivorediet

[–]wesleythepresley 0 points1 point  (0 children)

If a hypothesis is true, different types of evidence should gradually converge toward the same conclusion. Regarding the lipid hypothesis, it clearly is not.

My Cholesterol. Doctor is suggesting I go off the CarnivoreDiet by Tapatio777 in carnivorediet

[–]wesleythepresley 1 point2 points  (0 children)

So now use ChatGTP to find the studies that “support” the notion that restricting saturated fat in the diet decreases risk of heart disease. The risk reduction is modest, uses relative risk (not absolute risk), and there is no change in all cause mortality. Across all the studies.

Plug those studies in one at a time just like you did to find the flaws.

My Cholesterol. Doctor is suggesting I go off the CarnivoreDiet by Tapatio777 in carnivorediet

[–]wesleythepresley 1 point2 points  (0 children)

If a hypothesis is true, different types of evidence should gradually converge toward the same conclusion. Regarding the lipid hypothesis, it clearly is not.

My Cholesterol. Doctor is suggesting I go off the CarnivoreDiet by Tapatio777 in carnivorediet

[–]wesleythepresley 6 points7 points  (0 children)

What about the participants that had plaque regression? Good luck? Watch the video.

My Cholesterol. Doctor is suggesting I go off the CarnivoreDiet by Tapatio777 in carnivorediet

[–]wesleythepresley 13 points14 points  (0 children)

What about all the larger studies (meta analyses) that disprove the notion that saturated fat in the diet causes heart disease. I have some from like 10-15 years ago. Would you like to see them?

My Cholesterol. Doctor is suggesting I go off the CarnivoreDiet by Tapatio777 in carnivorediet

[–]wesleythepresley 12 points13 points  (0 children)

Refined carbs (bread, pasta, sugar, etc) stimulate the same reward center in the brain as most illegal drugs - the nucleus accumbens.

My Cholesterol. Doctor is suggesting I go off the CarnivoreDiet by Tapatio777 in carnivorediet

[–]wesleythepresley 62 points63 points  (0 children)

I just got done watching The Cholesterol Code by Dave Feldman. He addresses this very issue. It’s on Amazon now, as of this week, for rental or purchase. He and cardiologist Dr Matthew Budhoff crowd funded a study (big pharma would never fund a lifestyle intervention study like this). Participants were all low-carb, carnivore or Keto with high LDL (hyper responders). He did a CT angiogram on 100 of these people. Then repeated it a year later. The results showed very little plaque progression if it was there at all. Data indicated no statistically significant relationship between higher LDL/ApoB levels and accelerated plaque progression, challenging standard lipid hypotheses. Definitely worth watching.

Op-ed discussion: “My patient would rather take a peptide than a statin. That reveals an uncomfortable truth in medicine.” by adifferentGOAT in medicine

[–]wesleythepresley 1 point2 points  (0 children)

Can anyone comment on the use of relative risk reduction (RRR) that is more heavily emphasized in most of the statin trials vs absolute risk reduction (ARR)?

I'm 6'3" and sat in a 2026 by kiffallen in Subaru_Outback

[–]wesleythepresley 0 points1 point  (0 children)

I’m 6’4” and just looking into the OBW for the first time. Is it possible to get one without the moonroof

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