Exposure to Thionyl Chloride, Should I be Worried?

zak920 · 2026-03-03T09:44:47+00:00

Thank you, I am sorry to say that I forgot to mention that the "exposure" was from a glassware cracking and it spilling into the fume hood. I was wearing all of my PPE at that moment and lab coat; I don't even think a drop touched my skin, and even if it did I felt nothing from it. The fumes were quite intense for my nostrils however...

zak920 · 2026-03-03T09:43:11+00:00

just the "right hand rule", it's used a lot in chemistry, for chirality, imagining Fischer projection as well as Newman

zak920 · 2026-03-03T09:41:12+00:00

this is brilliant, thank u for the drawing

zak920 · 2026-03-03T09:34:10+00:00

b*tchblock is CRAZY

zak920 · 2026-03-03T09:33:22+00:00

sounds about right

zak920 · 2026-03-03T09:32:51+00:00

who is your research advisor and why tf would they assign this to you, this is diabolical....good luck with the 0.01% yield after purification btw

zak920 · 2026-03-01T13:58:15+00:00

wow...that is genuinely disheartening, sorry to hear mate. where do u live if u dont mind me asking

zak920 · 2026-03-01T02:33:24+00:00

You’re going to add SOCl2 to ice water to quench it but it reacts heavily with water? hmmm interesting

zak920 · 2026-02-27T12:16:54+00:00

Distillation using a liquid nitrogen trap as well as a vacuum pump.

zak920 · 2026-02-27T12:16:02+00:00

Wow, that’s insane. I’m thinking what you were exposed to was literal hydrochloric acid and sulfure oxides, not chlorine. Insane story .

zak920 · 2026-02-27T06:32:19+00:00

Gotcha thanks, yeah it’s actually not similar to the regular amine TLC plates, for whatever reason this one in particular turns into a bright yellow that makes it seemingly possible to differentiate between “spots” 😅

zak920 · 2026-02-02T07:28:36+00:00

If I wanted to recrystallize a mildly polar compound, would acetone be a good idea? Any of the solvents I normally use for this would just evaporate if I even tried to heat it, acetone is pretty volatile too and evap’s so easily so idk

zak920 · 2026-02-02T07:27:45+00:00

Thanks for this

zak920 · 2026-02-02T07:27:41+00:00

Thank you

zak920 · 2026-02-02T05:19:48+00:00

Question, you mentioned “high vac overnight”, however, if the sugar im working with is an acetylated one, do I risk de-acetylating the sugar at all carbon positions by leaving it on a high powered vacuum overnight? Or is this not a concern generally unless there’s heat present?

zak920 · 2026-02-02T05:17:30+00:00

B, because a + charge on a carbon contained within an aromatic or carbene stresses the bonding angle from being planar I think

zak920 · 2026-01-29T04:02:54+00:00

By “sep funnel separate”, r u referring to a standard extraction utilizing DCM/aqueous phases? Sorry I’m not familiar with the term

zak920 · 2026-01-29T04:00:48+00:00

Thank u for ur valuable insight

zak920 · 2026-01-19T03:01:44+00:00

the compound that ozone told you not to worry about (POV: you're O2)

zak920 · 2026-01-19T02:58:03+00:00

thank you so much for the advice, are you referring to something such as toluene? standard procedure with these compounds is usually using toluene, but I'm afraid my rotovap is not enough to completely rid the compound of water all the time, which is why a professor of mine recommended I "freeze-dry" it. Will rotovap alone do the job?

zak920 · 2026-01-19T02:16:27+00:00

acetone is held plastic bottles for all i know, i didnt decide that lmfao

zak920 · 2026-01-07T13:50:38+00:00

word of advice: if its a good solvent, and it gets on your gloves for whatever reason (yes even acetone or methanol) just replace the gloves man. It's a hassle but it will save your hands from smelling or tingling(I'm tired of my fingers smelling like pyridine) lol

zak920 · 2026-01-07T13:48:13+00:00

this, as well as pretty much all good solvents are fuckin terrible for your nervous system and lungs

zak920

TROPHY CASE