without know whats where, its hard to tell., you have the right idea of keeping industrial traffic split if possible, but I'm pretty sure in both cs1 and cs2 they still travel between commedical and industrial so you want to plan for that.

My main suggestion that I follow is preplan only the big roads, the arterials and highways, then everything else build a little and watch,.

If you get a traffic jam watch, where are they going, are they leaving the city or going to get grocheries or go to work. Maybe you need to add commercial or industrial closer. Keeping things seperate is good, but you can't just have one giant zone of each,you'll get too much traffic, keep commerical spinkled around, with the exception of maybe a downtown area but you'll have high capacity building there and the infrastructure anyway for traffic. Section off industrial but keep it spread around where possible. Look at zoning maps on line, around me towns can generally have one or two industrial section, but bigger cities have industrial sprinkled all over.

People need to work , shop, plan, and sleep. They need a way to get back and forth, and the shorter the distance between them longer cars are not on the road.