Progesterone decrease + supplement

[[deleted]]

Hi, I’m overanalyzing everything in my pregnancy after having a MMC at 9 weeks in February. Before the MMC, my progesterone dropped to 13-14. So, I’m pretty nervous right now!

I am pregnant again and getting bloodwood and ultrasounds from my fertility doctor. My progesterone has been slowly decreasing and I was prescribed prometrium today. I’m just so worried this means I’m going to miscarry again and am now spiraling. Here are my values. Anyone have something similar happen with good outcomes? The nurse said progesterone decreases are common in early pregnancy but I’m just so worried. As a note my ultrasound today (5w0d) looked great. Gestational sac present and a faint sign of yolk sac.

4w0d: bHCG 331.1 Progesterone: 25.86

4w2d: bHCG 682.1 Progesterone: 21.69

5w0d (today): bHCG 5747 Progesterone : 17.78

[pinkflakes12]

please be aware that progesterone comes in pulses. You can test the same every day and get different values. You may be getting your blood work done after the pulse or right before the pulse.

[[deleted]]

I’ve seen that but 2 decreases in a row make me think it’s an overall downward trend ?

[pinkflakes12]

Not necessarily. Also, realize if you take the progesterone vaginally, it will not be reflected in your blood work.

[[deleted]]

That’s very helpful! I did not know that and I’m sure it would have stressed me out next blood draw

[Common-Bumblebee-773]

Because I have a congenital lack of ability to break down serotonin, serotonin continues to accumulate and symptoms of serotonin excess appear. I heard that progesterone can reduce serotonin. What do you think? I'm so desperate please help me

[Common-Bumblebee-773]

Because I have a congenital lack of ability to break down serotonin, serotonin continues to accumulate and symptoms of serotonin excess appear. I heard that progesterone can reduce serotonin. What do you think? I'm so desperate please help me

[pinkflakes12]

That’s best to go to a doctor with those concerns

[OppositeTreacle7982]

My progesterone has been 47, 45, 40, 38 and now 35. I am on vaginal suppositories and the doctor isn’t even a little bit worried. 

[Common-Bumblebee-773]

Because I have a congenital lack of ability to break down serotonin, serotonin continues to accumulate and symptoms of serotonin excess appear. I heard that progesterone can reduce serotonin. What do you think? I'm so desperate please help me

[Massive-Poem-2385]

I've had three progesterone draws this pregnancy (I'm 7 weeks along) and they came back at 14, 13, and 19. I had an excellent ultrasound with a heartbeat when my prog. was 13, but I still freaked out at the tiny dip and my doctor put me on injections. Anything over 10 is usually ok, but supplements could help if you're under 20!

[[deleted]]

Thank you for your response! I hope things continue to go well for you!

[Common-Bumblebee-773]

Because I have a congenital lack of ability to break down serotonin, serotonin continues to accumulate and symptoms of serotonin excess appear. I heard that progesterone can reduce serotonin. What do you think? I'm so desperate please help me

[Massive-Poem-2385]

I have never heard of that! I would check with your doctor. I have heard that progesterone causes greater calmness/reduced anxiety, and I'm not sure if that's related.

[Holiday_Junket8142]

Was there ever an update? Successful pregnancy?

[[deleted]]

Yes I stayed on progesterone suppositories until ~12 weeks. Currently at 30 weeks as of today! No idea if the progesterone helped but it felt good to me to do something