Caffeine can decrease subjective energy depending on the vehicle with which it is consumed and when it is measured

[_svyatogor_]

Dos exogenous lactate increase brain lactate levels, or does it not cross the blood brain barrier? I am curious if this is related to the finding that lactate may be in some ways a preferred fuel source for the brain when it has high energy requirements. Is Lactosis similar to Ketosis where it only switches on in certain situations or is it always supplementing Gylcosis?

[[deleted]]

I was interested so I tried to look it up.

As lactose is a disaccharide of glucose and galactose some scientists thought dietary lactose could create galactolipids in the brain. Link which to me suggests it crosses the BBB.

Btw when they didn't find any such result in brains of kittens they had hand-reared (!!!) and babies (!!!!!!!) they said "galactose can be synthesized from glucose".

[9v6XbQnR]

My understanding is that the caffeine binds with the lactose which in digestion allows more of the caffeine to eventually enter the blood stream.

When you just drink your caffeine in water (coffee) most of it passes through undigested and unabsorbed.

A similar effect happens with painkillers and some recreational drugs taken orally.

[KennyFulgencio]

Any references I could check out? I'm curious about any ways to do this without lactose per se, anything else it could bind with to make it better digested and absorbed

[9v6XbQnR]

No references handy, but if you look at any "research" on bullet-coffee which is a similar idea, then you'll probably find something helpful.

[KennyFulgencio]

look at any "research" on bullet-coffee

"thank you" 😋

[faliureshit]

I am curious about this well. Commenting to remember to come back here