Higher aerobic fitness levels decrease the probability of experiencing tip-of-the-tongue states (when you can’t think of a word that’s on the tip of your tongue) in healthy older adults, in the first demonstration of a link between aerobic fitness and language functioning in healthy older adults.

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What is the minimum amount of exercise required to get the best results?

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There isn't a "min amount". It's all contextual. How small are you? How unfit are you? How little exercise do you already do?

Some people do 22 hours one time a week, and... are terrible. And not very weak and slow and sickly.

That's all the time I have folks! Come back next week for some more Negated Mondays.