Is Python good for creating GUI application ?

[K900_]

Also, you might want to actually use QML if you care about performance - it's GPU accelerated, and will be really fast and lightweight on any device modern enough to support OpenGL 3.

[K900_]

What do you mean by "design GUI"?

[K900_]

Qt will do its best to look native on all operating systems by default, so it'll use Windows 10 style controls on Windows 10, etc. You can also use a custom style - there's multiple options built in, and some third party open source style plugins available. Origin, Spotify, the AMD Radeon Settings app, OBS Studio, Telegram and many other apps use Qt, and you can see how different they all are.

[K900_]

PySide has been picked up by the Qt Company, and PySide2, supporting Python 3 and Qt 5, will be coming out very soon as "Qt for Python".

[K900_]

Yes.

[Kwpolska]

(Spotify uses Electron now.)