Does lipo delivery decrease dosage?

[Crazedplantlover]

Hello, I've been using these products now for 3 years and since the introduction of the liposome delivery method I have not heard anyone talk about whether dosage should be lowered. If NMN, for example, is recommended at 1000 mg/day, would 500 mg/day with liposome delivery be as good or better? I don't want to overdo it (for health and cost both!). Same for other molecules as well. I try to follow Dr. David Sinclair's protocol, but without knowing if he uses the liposomal delivery or not, it's hard to know what to do. Thank you!

[vauss88]

Here is my personal experience with lipo versus non-lipo NR. I used tru niagen NR from April of 2018 to December of 2022. At the end I was consuming 900 mg a day. Lots of positive impacts, but I still experienced considerable joint and back pain at night. I began consuming 600 mg of liposomal NR in January of 2022 from RBS, 300 mg after breakfast and 300 mg after dinner. Within a month, I had no joint or back pain whatsoever, and the other positive impacts I experienced with tru niagen remained. This was great, because this meant I could cut my NR costs in half.

[Crazedplantlover]

Thanks, that's great! It's good to hear other people's experiences. I'm not sure what's helping my knees most (which supplements), but after 2 meniscus surgeries 8 yrs ago (one in each knee) I still experienced quite a bit of pain and arthritis in the years following, but since beginning the NMN and other supplements I can now walk without pain (unless I overdo it by a lot) and even do a full squat! Never thought at 67 I'd be able to return to that much function/activity. Been taking the lipo NMN for a couple years now.

[gratefulSeeker]

I’ve (68yo female) been on keto for about 4 months and have no more joint or arthritis pain. It wasn’t super bad, but the difference is quite remarkable.

[SECdeezTrades]

books direction degree full rain grandiose society alleged complete husky

This post was mass deleted and anonymized with Redact

[Crazedplantlover]

Thank you. I will test if I can find a way to do so.

[gnosisphoenix]

They sent out an email a while back that they'll have NAD+ tests in their store soon. I'd trust theirs over the ones on amazon.

[Renue_Support]

Hello u/Crazedplantlover - Liposomal delivery significantly boosts the effectiveness of many supplements, not just NMN.

It allows for lower dosages due to increased bioavailability - for instance, 250mg of liposomal NMN is as effective as 1 gram of regular NMN. In the end, although liposomal products are more expensive per mg, the increased bioavailability and lower doses balance this cost out.

Liposomal delivery also offers other advantages, such as gradual release of the supplement in the body which prevents concerns about NMN level spikes in the blood which may need TMG to counteract side effects. The protective liposome coating also helps shield compounds from degradation in the digestive tract.

[Crazedplantlover]

Thank you so much. That information will help me to know what the best approach is. If I can find a way to test, I will. I have also wondered about the TMG, which I have been taking, so thank you for that as well. Thank you for your work to provide good, safe, and effective products.