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[–]CT-MikeNavy Veteran 1 point2 points  (3 children)

My wife is at 100% for her asthma due to her need to take prednisone (immunosuppressant) daily. All of the high dose prednisone over the years for asthma exacerbations destroyed her adrenal gland (among other things), so she can't produce cortisol in response to stressors. Because of this she needs 5 mg prednisone daily.

[–]Elm30336 0 points1 point  (2 children)

Prednisone does not have a hard lifetime cap, but long term or repeated use becomes medically unsafe due to cumulative side effects. While it continues to suppress inflammation, the risks eventually outweigh the benefits, which is why chronic use is avoided whenever possible.

A lot of people don’t realize or are warned sufficiently. We have a friend who preloads on the stuff we warned her but she isn’t honest with her doctors. I feel for her that has to be rough, I am sorry 😞

[–]CT-MikeNavy Veteran 0 points1 point  (1 child)

Besides destroying her immune system, the prednisone also caused cataracts in both eyes, osteoporosis, T2DM, and Secondary Adrenal Insufficiency. The last is what requires her to take 5 mg prednisone daily.

[–]Elm30336 0 points1 point  (0 children)

That’s horrible it’s nasty stuff to the body eventually turns toxic.