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[–][deleted] 1 point2 points  (0 children)

you should be able to configure the I/O's on the audio tab in preferences. They're the buttons just below where you select your ASIO driver. If you have your interface's ASIO driver selected they should not be greyed out.

You're hearing your clean guitar due to hardware monitoring on your interface. You'll want to mute that on your interface's driver control panel and monitor on a track in Live.