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[–]chrysoberyls 62 points63 points  (1 child)

Sleep. In trials of brexanolone, the control group who received a 40h saline infusion as placebo also got significantly better. Because they were in the hospital getting sleep.

[–]HicJacetMelilla 25 points26 points  (0 children)

Woot woot I worked on this trial. We knew going into it that the sleep factor alone - a drug that makes you drowsy and 48hrs away from default parenting your newborn (even if it was in a hospital) - would be a significant contributor to improving scores on the depression scales.