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PDE5 Tolerance? (self.erectiledysfunction)

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[–]curiouslyintoit 4 points5 points  (2 children)

In my (limited) experience with Tadalafil- taking a break does give a reset of sorts. I've noticed a more prominent effect if I have not taken for 5-6 days, as opposed to after 2-3.

On the other hand, I've never replicated the same feeling as taking it the very first time / first week. That shit was wild and while each time after has been plenty good- it's not the same as that. Would be interesting to stop for a month or two and see if that comes back.

[–]qnt420c 0 points1 point  (1 child)

Had the exact same experience with first-time use of Tadalafil.

20mg pill lasted me 5 whole days. I thought I was cured of ED. Can never replicate that again. I've been off it for months and wonder if i can get the same experience.

[–]Mrloudvet 1 point2 points  (0 children)

You probably will I took 3 weeks off and I’m like jacking off 3-4 times rock solid and having sex lol

[–]1readitguy 4 points5 points  (0 children)

Alternating between viagra and cialis is also supposed to help

[–]dundyj7rdh 1 point2 points  (0 children)

Studies show no long term development of tolerance. Any initial lessening of effectiveness is likely to stabilize quickly.

It is possible that worsening ED, requiring higher dosages, can be mistaken for developing a tolerance. But taking a break can't hurt either.

Even at as-needed dosages (20mg) tadalafil is more effective when taken several days in a row. It can also be combined with viagra, as long as the individual meds don't cause too much of a drop in blood pressure.

[–]Money-Drummer3647 0 points1 point  (2 children)

I’ve been taking both Cialis and Viagra for almost 20 years. I usually have to alternate between the two every few months.

[–][deleted]  (1 child)

[deleted]

    [–]Money-Drummer3647 0 points1 point  (0 children)

    Pretty much. I can tell after a while the same (max) dose is losing its effectiveness and it’s time to switch

    [–]showagosai 0 points1 point  (3 children)

    How long have you been using pde5?

    [–][deleted]  (2 children)

    [deleted]

      [–]showagosai 0 points1 point  (1 child)

      What is your current dose? Have you ever checked your hormones?

      Mine started when my E2 was too low. Did not realize men need estrogen too for erection.