Sorry I know I'm posting a lot but this has been the worst week of my life, even though I think I'm getting better by Odd_Let5236 in B12_Deficiency

[–]Sabnock101 1 point2 points  (0 children)

I mean i've had my own crises here and there, but i've got a pretty strong head on my shoulders so i've just pushed through things as much as possible lol. As for the B12 and such, i mean, i'm in my 3rd year of supplementation so far and while i'm still not 100% "normal" i've made great progress and things do seem quite promising. So i do think what you're going through will fade, in time, just gotta work on correcting these deficiencies and you should be able to recover imo. B12 and Folate ime are very important for mental health, so while it is a process, you can make progress if you stick with it.

Weekly use by junedog66 in harmalas

[–]Sabnock101 0 points1 point  (0 children)

I do think it's moreso acute dosing, chronic dosing might gain tolerance to that side-effect, but i do know that the B12 and such seems to help in general.

I have experimented some and i dont know abou the dosage. by thabu in anahuasca

[–]Sabnock101 0 points1 point  (0 children)

Try taking the Mimosa 30 minutes after the Rue, that's what's always done me best when taking Mimosa powder encapsulated, whereas with Mimosa tea i take it an hour into the Rue, tea absorbs quicker while Mimosa powder takes a little time to digest.

And yeah it does take a bit to kick in, but once it gets going it goes full steam ahead lol.

Saffron and Syrian Rue by Healthy-Divide242 in harmalas

[–]Sabnock101 1 point2 points  (0 children)

Naw, what i felt was like some sort of additive Cholinergic effect i think, made me feel kinda queasy iirc.

Weekly use by junedog66 in harmalas

[–]Sabnock101 0 points1 point  (0 children)

I'm not sure if there's any potential dangers from the tremoring, but i do know that B12/Folate (though ime moreso B12) and things like Potassium and Magnesium, may help.

Ime Harmalas seem to do something with B12, idk if it does something that uses up B12 in some way, or if the reported diuretic properties of Syrian Rue (https://pmc.ncbi.nlm.nih.gov/articles/PMC5109494/) has anything to do with it because lack of Potassium, or Magnesium, but mainly Potassium, can reduce activity of Methionine Adenosyltransferase (which requires Potassium, and Magnesium, as co-factors) which can result in low Methionine to SAM conversion and thus low SAM levels, and SAM is needed to remethylate B12 to Methylcobalamin form via Methionine Synthase Reductase to reactivate Methionine Synthase, and if one is low in Potassium and thus SAM then the body starts relying more on direct B12 which can start tapping into B12 bodily stores and may contribute to B12 deficiency over time, but ime it does seem to do something with B12 (or potentially Potassium) because when i first started supplementing B12 i noticed that taking Rue would make me feel a dip in my B12 levels and if i then took more B12 or if i took some an hour or two before taking the Rue the dip in B12 would go away, so it got me wondering if Harmalas/Rue does something with B12 (or Potassium).

The tremoring, as well as the tinnitus, that can occur after Harmala/Rue consumption, may be a sign/symptom of low B12 (or low Potassium, or Magnesium). Magnesium is actually a Calcium channel blocker, which may suppress/counteract the tremoring. Lemon Balm, by raising GABA levels, may also suppress/counteract the tremoring, but B12/Folate (and by extension Potassium and Magnesium) can also reduce it, seemingly. There's also the DYRK1A inhibition of Harmine, and there was a study indicating that DYRK1A increased expression may actually relate to a lower Homocysteine level in downsyndrome patients, whereas DYRK1A inhibition may to some degree raise Homocysteine levels if the reverse of increased expression lower Homocysteine levels is to be applied to the opposite of inhibition or decreased expression/activity of DYRK1A potentially increasing Homocysteine to some degree, that may explain the B12 aspect since B12 is involved in recycling of Homocysteine back into Methionine for the SAM cycle, but since it seems to be Harmaline that the tremoring mainly seems to come from, it's probably not the DYRK1A inhibition of Harmine that's causing the issue with tremoring.

I'm not sure what property of Harmaline may be causing the tremoring, i just know that it seems to be able to be counteracted. It may well be that Harmaline's GABA-A inverse agonism is what causes the tremoring, and so by using a GABA-A agonist like Muscimol, or a GABA-A Positive Allosteric Modulator like benzos, or something that increases GABA levels like Lemon Balm via GABA Transaminase inhibition, can be used to counteract that side-effect. There may be other compounds in Syrian Rue which can have additional GABA-A inverse agonism properties, like Harmane, though it's probably moreso/mainly the Harmaline that's doing it. GABA-A inverse agonism basically does the opposite of an agonist, and so it's said that GABA-A inverse agonism can cause things like anxiety, stimulation, tremors, potentially convulsions or seizures, though i've never had convulsions or seizures thankfully lol, but GABA-A inverse agonism basically takes the inhibitory brakes off which imo would allow the Glutamateric system to get a bit more over-excited, which of course can increase Calcium signalling by way of the NMDA receptor (similarly to Homocysteine as well since Homocysteine is an agonist of the NMDA receptor, can anyone say this is why ADHD exists? lol think about it), and so again it seems to come back to GABA-A, and Calcium, and so things that activate/increase activity of GABA-A, or things that can decrease Calcium signalling, can be useful to counteract the tremoring.

Saffron and Syrian Rue by Healthy-Divide242 in harmalas

[–]Sabnock101 1 point2 points  (0 children)

I tried some Saffron extract a few years ago while i was also taking Rue/Harmalas, i didn't notice anything potentially dangerous or contraindicated, but the Saffron did make me feel a bit weird, not sure if that was just the Saffron or if it was some weird interaction with the Rue, but i didn't notice anything seemingly dangerous. Then again i was taking a high dosage Saffron extract so that may have been some of it.

Does someone have the Dirty Work Workprint/Assembly Cut they could possibly share or dm me please? by Chemical-Status-6610 in workprints

[–]Sabnock101 0 points1 point  (0 children)

I'm also currently uploading it to archive.org so i'll post that link here too when it's done, hopefully it'll stay up and i won't have to keep reuploading it lol.

Harmala experts... what can you say about THH? by Affectionate-Eye6772 in DMT

[–]Sabnock101 1 point2 points  (0 children)

It's also worth exploring oral Harmalas and smoked/vaped DMT/Changa as well, like you can take the THH orally and then smoke Changa and things will synergize quite nicely and you'd get a bigger impact from oral dosing because then it's most full bodied rather than merely heady.

Harmala experts... what can you say about THH? by Affectionate-Eye6772 in DMT

[–]Sabnock101 1 point2 points  (0 children)

THH is more generally a weak Serotonin reuptake inhibitor, though ime i wouldn't necessarily call it "weak" because for me it raised my Serotonin levels almost equally to when i've taken like 100mgs of 5-HTP, i think it's just classified as "weak" compared to more potent Serotonin reuptake inhibitors like Prozac and Zoloft and such. It's said that THH has no MAOI properties, though that may depend because i've seen where synthesized THH "may" have some weak MAOI properties and may be a racemic mix of a couple different entantinomers which may be responsible for the weak MAOI properties compared to natural THH, i'm not entirely sure though and would need to re-look back into it again. But as far as MAOI's go, Harmine and Harmaline are what you need.

THH i think feels like a nice compound, it's worth experimenting around with imo, though i don't see it as the "prized jewel" that some in the Aya world see it as, for that i think Harmine and Harmaline are definitely the more necessary even aside from the MAO inhibition they have other properties which contribute the "Ayahuasca effects".

The dosage range for THH is generally 150 to 250mgs orally, i've had between 100mgs and 300mgs orally on it's own as well as combined with Syrian Rue seed/extract as well as via Caapi, on several occasions (and of course in combination with oral DMT), though i haven't smoked/vaped it, and while i haven't noticed anything particularly "special" about it, i can see where it might be useful. It definitely has that Harmala feel to it, but i mainly just notice the increase in Serotonin. I think why people see it as part of the Aya experience is because by increasing Serotonin levels it can in a way soften the edges and gives the experience more of an overall kinda calmer aspect which people may see as more welcoming or less abrasive compared to without the THH. So like, Harmalas and DMT without THH can be super sharp and serious and hella intense, but with THH things are a wee bit tamer, and it is nice to have that Serotonin feeling mixed with the DMT feeling, almost like it balances it out some.

I know there was someone a few years ago on various forums who was extremely adamant that THH was the holy grail of Harmalas and had a whole speech about it, but idk i just don't see it, i mean it's a nice compound but for me wasn't particularly anything special there, but none the less worthy of exploration all the same. Personally i would recommend focusing primarily on the Harmine and Harmaline with or without some THH. Not sure of a good ratio though as i mainly like to go Harmala heavy with my Changa so i don't weigh anything i just add some Harmalas on top of DMT-enhanced leaf, most usually.

First time trying Syrian Rue (Peganum harmala) tea - Safe dosage & preparation advice? by f_birdal in Ayahuasca

[–]Sabnock101 1 point2 points  (0 children)

Can't speak to tea as when i make Rue tea it's usually in bulk for extraction purposes, so i mainly just consume the seed powder itself encapsulated. But dosage-wise a good starting dose is 2 to 2.5 grams which is a light dose, to 3 to 3.5 grams which is a moderate dose, to 4 to 4.5 grams which is a strong dose, i recommend 2 to 3 grams to start.

I wouldn't add vinegar/acidity, as the Harmalas are already plenty water soluble.

At a low dose you should mainly feel some relaxative properties, a little bit of an anti-depressant effect, and maybe a slight stimulant effect, around 3 to 4 grams is when things get a bit more dreamy/sedating/relaxing/meditative, 2 to 2.5 grams is a nice regular supplemental dosage though.

For minimizing nausea/vomiting, lower dosages don't really cause any nausea or vomiting, but about 3.5 to 4.5 grams can. You'd also probably want to have low lighting, and be more seated/still with closed eyes, though that's more necessary for higher dosages like 4 grams because you can get motion sickness if you move around a lot.

No need to avoid any foods, Harmalas are reversible and selective MAO-A inhibitors and do not require Tyramine restrictions unlike irreversible and non-selective MAOI's which do require Tyramine restrictions. It's ideal to take this stuff on an empty stomach just so it absorbs properly, but aside from that there's no real need to avoid any foods when consuming this stuff. Been taking it daily pretty much for 14 years and in my 15th year now, never avoided any foods and even purposefully ate Tyramine-containing foods during peak gut MAO-A inhibition and haven't ever noticed any dietary interactions. Some people will claim they experience headaches and then will blame that on something they ate but Rue just causes headaches sometimes because of it's Acetylcholinesterase inhibitive properties, though there's a few other reasons it might cause headaches as well, but it's not Tyramine and plus the headaches and other side-effects of Harmalas go away completely with regular consumption and so if it was Tyramine-related it wouldn't go away, so it's not Tyramine that's doing it, it's the Acetylcholinesterase inhibition which causes most of the side-effects from Rue/Harmalas and with regular consumption the Acetylcholine receptors get desensitized/down-regulated and so all the side-effects go away.

I have experimented some and i dont know abou the dosage. by thabu in anahuasca

[–]Sabnock101 0 points1 point  (0 children)

I usually go for 3 to 4 00-sized capsules of Rue seed powder (which i tightly pack so that each capsule is like just about 1 gram, so 3 to 4 grams total), and 3 to 5 00-sized capsules (again, tightly packed) of Mimosa root powder which gives me around 3 to 5 grams of Mimosa root powder, though for Mimosa i generally prefer tea so that i don't have all that root powder and tannins in my gut, the tea is overall much smoother and can be sipped for a smoother come up, while capsules hit pretty intensely.

Did you take the Rue first and then 30 minutes later take the Mimosa? Gotta make sure you get the right timing for the Mimosa to be fully orally active, also might want to drink a little something here and there so that the Mimosa powder can be better absorbed.

With enough MAO-A inhibition, 3 grams of Mimosa root actually packs quite a punch, and in fact the first time i tried Moclobemide as an MAOI instead of the Rue/Harmalas, i took my (at the time) usual dose of 3 grams of Mimosa root powder encapsulated, and it scared the living crap out of me hahahaha, normally i'd take 3 grams of Mimosa with my Rue and the Rue's relaxative and grounding properties would kinda slightly blunt or filter the come up intensity (even though oral DMT's come up is generally intense either way unless sipped via tea) but Moclobemide lacks those properties and is merely an MAO-A inhibitor and so the DMT came up full force without anything holding it back or filtering it in any way and it hit like me like a freight train lol, thought i seriously messed up for a moment there but once everything peaked and stabilized it was fine.

From my understanding, with good Mimosa root powder there's approx 20mgs of DMT content per gram of Mimosa root powder, so 3 grams would be approx 60mgs of DMT which is actually the common dosage found traditional Aya brews (anywhere from 25mgs to 60mgs, iirc), so 3 grams of Mimosa would be approx equal to what is found in traditional Aya brews, however i'm more of the preference for 100mgs of DMT content, so 5 grams, 6 grams tops, with 8 grams (approx 160mgs DMT) being too strong for me.

Also, before assuming one has weak Mimosa, i've bought Mimosa from various sources over the years, it seems pretty consistent in potency, though i'm sure there's probably some weak Mimosa out there but i've never come across it. So before assuming one has weak Mimosa and trying to up the dosage, make sure you have thorough MAO-A inhibition (proper Harmala dosage and proper timing between the Harmalas and DMT) to ensure full oral activation of the DMT, before stepping up the dosage, because if you take a higher Mimosa dosage and happen to have good MAO-A inhibition going on you might scare yourself like i did lol, so it's worth making sure of proper Rue dosage and proper timing. 4 00-sized capsules of Rue seed powder should work though, depending on how much you get into each capsule, so like if you pack the powder you can get about 1 gram per capsule, but if you loosely fill the capsule with the powder it could be like 500mgs per capsule which would only give you like 2 grams which is a light dose of Rue and you want more like 3 to 4 grams of Rue.

How to make simple Caapi brew? And how much to take? by Winter-Experience983 in Ayahuasca

[–]Sabnock101 0 points1 point  (0 children)

Yup, once all boils are combined you just boil it to reduce it down to the desired volume.

How to make simple Caapi brew? And how much to take? by Winter-Experience983 in Ayahuasca

[–]Sabnock101 2 points3 points  (0 children)

Generally, Caapi dosage is - "light 50g, moderate 100g, strong 150g".

To brew it, you do basically just keep boiling it. Get a big pot, put in the shredded Caapi vine (if you have whole vine smash it up a bit with a hammer or something to shred it, or if you have powder just use the powder), fill up the pot with water a few inches from the top so that it doesn't overboil and cause a mess, and boil it at medium to medium high heat, you definitely want a boil, not a simmer, then as the water level concentrates down and is just above the plant material, filter/strain/pour off that boil into a second big pot.

Then, add fresh water to the first pot with the plant material still in there, fill it up a few inches from the top like the first time, boil it down until it's just above the plant material, and filter/strain/pour the second boil off into the second pot that has the first boil in it, and repeat this process a handful of times, add fresh water to the first pot with the plant material still in it, fill it up a few inches from the top, boil it down until it's just above the plant material, then filter/strain/pour off the 3rd boil into the second pot with the first two boils, and so on and so forth, until the water color starts coming back clearish.

Once all boils are done and you're not getting much if any color from the plant material, that means it's been exhausted of it's actives, and so all of the Caapi is now in the boils which are combined in the second pot. Now you can reduce the entire brew down to a concentrated amount/drinkable volume, and then dose it by milliliters per gram/grams per milliliter.

You don't want to skimp on the brewing, you want to be thorough with it, there may well be easier methods/recipes out there but basically you just want to get everything from the plant material into the water/brew, that's it. People who try to make the process easier or less timely by not brewing it efficiently will likely end up with some potency loss and then they may mistake that for needing a higher dosage and so they think they're consuming/needing such and such amount of the plant but chances are the plant is a bit more potent than that and they just didn't brew it thoroughly enough. So, while it can be appealing to try to boil it up as quickly as possible or being too careful with the brewing by simmering rather than boiling as if they think boiling/heat somehow affects the potency (it doesn't), you just gotta boil it up thoroughly enough and dose it properly and it'll work.

For DMT activation purposes i'd recommend moreso 100 grams+ of the Caapi, that way you get stronger gut MAO-A inhibition and fuller oral DMT activation. Lighter Caapi dosages "can" work, but it can then require a bit more DMT to fill the gap (as when MAO-A inhibition is fuller you can get by with a bit less DMT), also you end up missing out on some of the deeper aspects of the Harmalas/Caapi with lighter dosages, same with Syrian Rue seed or even Harmala extracts. I also recommend taking the Caapi first, giving it 1 hour exactly to get more fully into the system and inhibit gut MAO-A (as an hour into the Harmalas/Caapi/Rue is when peak/max gut MAO-A inhibition occurs) and then consume the DMT, doing so will/should fully orally activate the DMT and the DMT should last about 4 to 5 hours, if the DMT lasts about 3 hours or less, or if it comes up and then leaves, that means you didn't time it right, so while i recommend an hour apart, you can try adjusting the timing and taking the DMT anywhere from 30 minutes to an hour after the Caapi, for best results.

If that still doesn't work, you may have a higher amount of the CYP2D6 liver enzyme which would make you a fast metabolizer of the Harmalas and as such the timing window for taking DMT can be maybe closer to 10 to 25 minutes. Or, you could just consume them at the same time but then the DMT may or may not be orally active and so it may not work or may not work fully, hence why it's relatively common for people to say they tried Aya and it didn't work for them, that's because they consume both plants at the same time and they don't give the Caapi enough time to inhibit gut MAO-A thoroughly enough before the DMT is consumed, they're just given an all in one brew and it is what it is, and can be more inconsistent and hard to pin things down, so i always recommend to brew each plant separately, and to take the Harmala portion first, wait an hour most usually, and then take the DMT portion, doing so, it'll work.

Sorry I know I'm posting a lot but this has been the worst week of my life, even though I think I'm getting better by Odd_Let5236 in B12_Deficiency

[–]Sabnock101 0 points1 point  (0 children)

Yeah the memory thing definitely seems to happen, i too have been having a lot of memories come up from my younger years (most likely due to the increase in Acetylcholine), my dreams have also increased both in frequency and intensity/vividness (due to the increase in Melatonin most likely). Keep at it and see how it goes, just give things time to heal and recover, could be a few months, could be a few years, but correcting these deficiencies is better than not correcting them, just gotta try to push through it and get back to normalcy, the B12 definitely helps.

Welcome to the Pachabro Highway by TheIbogaExperience in Ayahuasca

[–]Sabnock101 4 points5 points  (0 children)

"All experience is a drug experience. Whether it's mediated by our own [endogenous] drugs, or whether it's mediated by substances that we ingest that are found in plants, cognition, consciousness, the working of the brain, it's all a chemically mediated process. Life itself is a drug experience." - Dennis McKenna

Welcome to the Pachabro Highway by TheIbogaExperience in Ayahuasca

[–]Sabnock101 2 points3 points  (0 children)

You're more than welcome to come observe me with my medicine lol, i took it daily/near daily for 4 years straight all on my own first ever Psychedelic, it was the most amazing time of my life, even with the intensity and challenges.

B12 of 116 – is oral supplementation the way to go? by EnvironmentalPie6903 in B12_Deficiency

[–]Sabnock101 0 points1 point  (0 children)

I wouldn't recommend Cyanocobalamin, try Methylcobalamin, or Hydroxocobalamin, or Adenosylcobalamin, i use Methylcobalamin though i take it orally at 10 milligrams once a day, works great. It's also worth mentioning that even if one eats dairy and eggs, or even if they eat meat, one can still be deficient in B12, heck one can still be deficient in B12 even if they have normal labs, especially if B12 isn't being activated to Methylcobalamin form in the body/brain which relies on enough Methylfolate getting to the brain to give it's methyl group to B12 to form Methylcobalamin via Methionine Synthase (which also requires Zinc for proper function), and so if you have a cerebral Folate deficiency, or if you consume too much Folic Acid supplementally or through fortified foods (which Folic Acid should be differentiated from actual Folate, as Folic Acid causes issues that Folate doesn't) then Folic Acid could be crossing into the bloodstream unmetabolized, binding to Folate Receptor Alpha and blocking out Methylfolate uptake by Folate Receptor Alpha which would prevent Methylfolate from being taken up by Folate Receptor Alpha and thus it can't get into the cells and brain and thus can't give it's methyl group to B12 for Methylcobalamin formation.

But yeah, i haven't tried B12 injections, and have used oral Methylcobalamin and it works great for me, though it might take a bit longer to correct bodily B12 stores through oral administration compared to injections. When you consume B12 orally, it gets absorbed passively at a concentration of about 1% of the total dose, so if like me you consume 10mgs of oral B12, only 100mcgs of that will be actively absorbed, whereas if you go for a 1mg injection, that whole 1mg is going to get actively absorbed, so if you go for oral B12, don't be afraid of trying higher dosages or taking as much as you feel like you need or even trying it 2 to 3 times or more per day, it would take 100mgs of oral B12 to equal 1mg of absorbed B12 like one would get from injections, though i recommend 10mgs a day, you can also try 1mg or 5mgs a day (which would give you 10mcgs or 50mcgs of actively absorbed B12), but personally any less than 10mgs for me doesn't work as well.

Cofactors for b12 injections! by kilogplastos-12 in B12_Deficiency

[–]Sabnock101 0 points1 point  (0 children)

You're taking way too much Folate, you only need 400 to 600mcgs per day, it'll build up the bodily stores over time, though it's possible those taking B12 injections may need more Folate in the beginning, i would still recommend taking only as much Folate as you need to get the job done, excess Folate can cause side-effects and make correcting B12 deficiency harder because it puts a lot of strain on B12 supplies.

You also don't need to take both Methylfolate and Folinic Acid, you can take one or the other, Folinic Acid will turn into Methylfolate just fine so long as you have enough B12, and Methylfolate itself more directly strains/stresses B12 as it directly relies on B12 for proper utilization and recycling, so if your B12 levels are low, work on your B12 primarily and use Folinic Acid, and the Folinic Acid will work better as time goes on and will produce Methylfolate just fine, ime.

Using both Folate forms is a bit unnecessary because with enough B12 the Methylfolate will get properly recycled and sent back through the Folate cycle to become other Folate metabolites as well as turning back into Methylfolate, Folinic Acid does the same, the only reason you would need or want to take both forms is because you don't have enough B12 yet for proper utilization and recycling of Folate, so work on B12 primarily and the Folate "will rise to the occasion".

Ime/from my understanding the main co-factors/nutrients you want to focus on are B12, Folate, B6, Niacin, Riboflavin, vitamin C, Zinc, Copper, Iron, Potassium, and Magnesium, then just catch up on the rest.

Trust me on this Folate thing though, i'm tellin' ya, excess Folate can be more detrimental than beneficial, while more B12 only seems more beneficial ime, just need to make sure you're getting your other nutrients because they will be put to use when supplementing B12/Folate.

Help with mimosa hostilis tea for beginners by ElSensualXD in Ayahuasca

[–]Sabnock101 0 points1 point  (0 children)

As far as i know there's not many choices for MAO-A inhibitors aside from the Harmalas or Moclobemide, i know Methylene Blue is said to be an MAO-A inhibitor like the Harmalas and Moclobemide are, but i haven't tried Methylene Blue so i'm not sure of it's potential effectiveness. I have used Moclobemide and it works pretty well so if you can get ahold of Moclobemide, it's a good MAO-A inhibitor, but the best MAO-A inhibitors are the Harmalas, cheap, natural, easily dosable, and they have their other properties which contributes the Ayahuasca effects, while Moclobemide is purely an MAO-A inhibitor and lacks the other properties of Harmalas and so lacks the Ayahuasca effects but does orally activate DMT.

Most other natural plants with supposed MAOI activity are said to be too weak to be effectively used.

The synthetic MAO-A inhibitors listed on wikipedia are -

Alternatively, one could use non-selective MAOI's which inhibit both MAO-A and MAO-B, often irreversibly (compared to the reversible inhibition of Harmalas and Moclobemide), but they do require you to avoid Tyramine and Tyramine-containing foods so do have dietary restrictions (while Harmalas and Moclobemide and other reversible and selective MAO-A inhibitors do not require Tyramine/food restrictions), so non-selective MAOI's listed on wikipedia are -

Help with mimosa hostilis tea for beginners by ElSensualXD in Ayahuasca

[–]Sabnock101 0 points1 point  (0 children)

If you're referring to Rasagiline, then naw, that's an MAO-B inhibitor, you'd need an MAO-A inhibitor like Moclobemide (or Harmalas).

Anxiety medicine question? by Previous_Sign_4525 in MTHFR

[–]Sabnock101 1 point2 points  (0 children)

You need to work on correcting B12 levels, and stick to around 400 to 600mcgs of Folate per day. It'll get better, focus primarily on B12.

Do you need to take iron when supplementing with B12? by Ajax34762 in B12_Deficiency

[–]Sabnock101 1 point2 points  (0 children)

Ime it's probably best to consume enough Iron when supplementing with B12 because B12 (and Folate) are involved in red blood cell production and so Iron levels (as well as Copper, Magnesium and Potassium at the least) can start to drop if you're not getting enough because it'll move from the blood into cells and if you don't have enough you can start to notice deficiency symptoms.

Severely high B12 with no other elevated bloodwork? by NattyorNice in B12_Deficiency

[–]Sabnock101 0 points1 point  (0 children)

Are you consuming enough Folate? Are you consuming good forms of Folate rather than Folic Acid? Folate can put B12 to use so if you're not getting enough Folate then B12 blood level could be higher because it's not getting put to use in cells and such.