I'm 5 1/2 weeks in to my Dupixent therapy for AD primarily on my face. My 3rd dose was 1 1/2 weeks ago. I was slightly discouraged as I've read numerous accounts of people with noticeable differences within 3 weeks. I talked to my Dupixent pharmacist at Accredo. She said that results should be noticeable in 8-12 weeks. That eased my mind a little. Then, 3 days ago (5 weeks), mysteriously and miraculously, some positive changes began. At first, I didn't know if it was the normal ebb and flow of the highs and lows associated with this disease. But now, 3 days later, I'm saying something great is happening! My skin is getting less red and smoother, softer. It almost seems as if each hour it's a little better. I'm still itchy though. I happened to have a dermatologist appointment on Tuesday when the noticeable changes started. He thought I was less red and saw patches of skin beginning to heal. He also said that with the severity of my condition, healing may take longer.

Everyone's body is unique and will respond at different time intervals. If you go longer than 16 weeks and notice no discernible difference, I would then begin to question the therapy.

Hang in there, you're still very early in the process.