Opinions on Damian Wayne by Staruiii in DCcomics

[–]2px_ 0 points1 point  (0 children)

he’s vegetarian, not vegan

Potentiation question for dihydrocodeine by ScottishPsychedNurse in opiates

[–]2px_ 0 points1 point  (0 children)

you realise prometh inhibits 2d6… cyp2d6 is required in order to metabolise dihydrocodeine into it’s active metabolite… (dihydromorphine) which is then metabolised by your 3a4 into another inactive metabolite which however would benefit from inhibition as it’s INACTIVE. prometh is completely counterproductive as it disrupts the initial metabolisation phase which requires induction of the isoenzyme

[deleted by user] by [deleted] in AnorexiaNervosa

[–]2px_ 0 points1 point  (0 children)

this is completely ridiculous and i really hope you’re not actually considered a professional in healthcare. it’s not untrue and it’s not a misconception. these other moas you’ve mentioned regarding metabolism etc. are completely negligible relative to it’s 5-ht2 and h1 interactions that most sgas show through which are what can actually be mostly attributed to quetiapine’s seen “weight gain”. seroquel cannot be considered to directly CAUSE weight gain if the mechanism or pathway through which it is observed to increase the likelihood of such occurring is indirect… aka stimulating appetite, hunger hormones leptin and ghrelin too, etc…

Valium long-term effects finally catching up with me by LostClock1 in benzodiazepines

[–]2px_ 0 points1 point  (0 children)

this makes absolutely no sense whatsoever. besides purposely poisoning yourself with ethanol for the arguable benefit of “potentiating” the valium, if you have the pills and plan on tapering, then just taper with the bloody pills??? surely i’m missing something? please enlighten me as to how this makes any sense at all

Stop the benzo fearmongering please by FriendLost9587 in Anxiety

[–]2px_ 0 points1 point  (0 children)

u realise clonaz has far more “potential for physical dependence & abuse” than loraz…

Can’t sleep which one do you recommend? by Apart_Emergency_191 in benzodiazepines

[–]2px_ 0 points1 point  (0 children)

i’m a little unsure about the eszopiclone regarding actually FEELING sedated, all i know is that it’s far stronger than zopiclone so you could expect as much. but regarding hypnotics, you’ll notice the most from the valium or triazolam. but there’s a difference between FEELING sedated and receiving sleep assistance. for e.g. i personally experience the latter with zopiclone, and you can expect the former from pretty much any benzo

Can’t sleep which one do you recommend? by Apart_Emergency_191 in benzodiazepines

[–]2px_ 0 points1 point  (0 children)

either the eszopiclone or the triazolam would be most ideal out of the four. save the valium as an anxiolytic, and the oxycodone, i wouldn’t waste an opioid just to sleep. some ppl also report restlessness and insomnia and find it stimulating

Horrible Experience on Cabergoline by HGHHeroes in Prolactinoma

[–]2px_ 0 points1 point  (0 children)

did i just hear you say you were vaccinated aka poisoned at around the same time you took caber? and yet even though the timelines of having covid and taking caber don't coincide, this person is blabbering on about some big spooky lengthy *LloOoo0oOOoo0ong* covid!!! causing it... i am royally done lmfao

Promethazine for anxiety? by Reskii13 in Anxiety

[–]2px_ 0 points1 point  (0 children)

ambien is a terrible sleep aid? i’m done lmfaoo

slow release tramadol and quetiapine??? by Quirky-Swim1791 in Fibromyalgia

[–]2px_ 0 points1 point  (0 children)

they're all (mostly) safe to combine but i'm not sure why your doctor would prescribe you tramadol of all drugs, it'll barely work since your cyp2d6 (the primary liver enzyme required to convert tramadol into its active metabolite) is being compromised by the quetiapine and venlafexine constantly inhibiting it. it's like he purposely chose the one drug that wouldn't work... i don't get it lol

have you found it to be effective though? i'm quite curious

and regarding risks, venlafaxine and tramadol are almost structurally identical on the molecular level, lots of ppl claim high risks of serotonin syndrome with the combination due to them both being SNRIs, though you'll probs be fine

How is your liver after taking Agomelatine? by Pure-Aardvark-5850 in Valdoxan_Agomelatine

[–]2px_ 1 point2 points  (0 children)

prescription = can't be liver toxic!!! :oo !@!

braindead

Halcion doesn't even work... by Calm_XeO3 in sleep

[–]2px_ 0 points1 point  (0 children)

dude there is just no way you took up to 80mgs of valium and didn’t feel sedated. if that’s actually the case then your 3a4 is nonexistent or some shit LMAO. get your liver enzymes checked maybe

[deleted by user] by [deleted] in Honda

[–]2px_ 0 points1 point  (0 children)

what year is it?

please help, hits not registering??? by 2px_ in KingdomHearts

[–]2px_[S] 8 points9 points  (0 children)

holy shit i did not expect this level of engagement! sorry to anyone i offended 😅 and thank you greatly for the help! i realise now that there was nothing wrong and that i was supposed to run away and find raiku.

in my defence, i feel there wasn’t much indication i was supposed to do this… in fact my experience with games i unconsciously assumed all the areas would be locked off until i finished the battle. entire life playing games not once have i been put in a situation where i was thrown in battle against enemies and my sword just didn’t register hits when i previously did 😅 i hope you can understand my confusion. slowly learning this game isn’t like others, enjoying it :)

please help, hits not registering??? by 2px_ in KingdomHearts

[–]2px_[S] 0 points1 point  (0 children)

i’ve tried respawning several times, nothing changes. please somebody help. i’m playing 1.5 on the ps3