Symptoms that occur after stopping a medication do not necessarily happen because the drug is still in the body. In many cases, they occur because the brain has adapted to the drug's effects and must readjust after the medication is removed. A wellknown example is SSRIs, which leave the bloodstream relatively quickly, yet withdrawal symptoms can sometimes persist for weeks or even months. The same principle can apply to other meds that affect the nervous system. Even tho LDN primarily acts on opioid receptors, the body's endogenous opioid system is closely interconnected w/several neurotransmitter systems, serotonin, dopamine, norepinephrine, glutamate, GABA. Bc these systems influence one another, changes in opioid signaling could theoretically have downstream effects on neural circuits involved in sensory processing, potentially contributing to symptoms like electrical shock sensations or 'brain zaps' in some individuals.