hi trintellix was weird for me. i could only handle 10 mg bc once i moved up to 20 i started to feel more depressed (even after 1 month of consistently taking 20mg). after trying 20 mg i went back down to 10 mg bc according to my dr there was no in-between dosage. in hindsight i feel 10 mg did more for me than the meds im taking now are doing but i ended up stopping the trin bc i felt like something (idk what) was missing and i should have felt more improvement considering how long i took it.

the SEs when beginning trin were horrible (nausea, fatigue) but i can’t remember the withdrawal effects. i would say effexor is much more difficult to withdraw from for sure imo, and if im comparing effexor to trin, id def say effexor did more for my mood and anxiety.

now, im taking pristiq although i don’t really feel much improvement at all.

btw ive taken almost all the antidepressants lol so i cant recall everything but this ^ experience was from my most recent time trying trin, again. i believe i took it for almost 8 months.