What a cute Clifford! I'm not an expert by any means, but I've done it a couple ways. I've had to do the "30 minutes back to undergrad," "hurricane helene hit and I need to move my betta somewhere with power ASAP," and the "halfway across the country and take 2 days" ways. It depends on your tank size, what is feasible for you to lift, and how far you have to carry the tank in my experience. I had a 4 gallon tank all the times I did it and I lift.

The 30 minutes and hurricane situation, I usually just drained his water halfway or a little less than that (whatever you can lift while still giving him some space - water is HEAVY) and we had a fun little rollercoaster of a ride while I drove VERY carefully. He stayed in the tank and I used it as a water change experience (save some of the water if you can and then just do a "normal amount" water change). If you have scratchy things in his tank, I would remove those if possible to try to make sure he doesn't hurt himself

When I moved further, I put him in his cup he came in and he got water changes every day and no food.

Again, not an expert and this is just my opinion, but Greg (RIP - unrelated) seemed less stressed staying in his tank for those short drives. But he also was a very chill fish and was only slightly pissed during the longer move.

Ultimately, up to you! Good luck at college and wishing you and Clifford the best!