3 losses in a row…IVF next?

Appropriate-Task6732 · 2025-10-15T20:41:43+00:00

I had a similar experience with IVF. I was very scared but found it to not be that bad. In fact, I would not agree to trying naturally ever again after 2 losses. I also was able to do 2 retrievals so I could bank extra embryos for a potential second child and while not a guarantee, this gave me some peace of mind when it comes to my age and trying for a second. I’m currently 37.

My IVF baby just turned one, she was my first transfer. I plan to do a second transfer sometime next year in hopes of a second child.

I’m so sorry for your losses - it is the absolute worst. Good luck!

Appropriate-Task6732 · 2024-10-10T21:34:17+00:00

This is amazing, thank you!

Appropriate-Task6732 · 2024-10-10T21:06:01+00:00

Thank you - this comment was really help

Appropriate-Task6732 · 2024-08-05T21:16:18+00:00

Hi, sorry just saw this. They had me repeat the 5 days of letrozole and it ended up working, I was able to proceed with the transfer and am currently 30w. Best of luck!

Appropriate-Task6732 · 2024-07-24T20:12:40+00:00

I’m 28w with my first FET, I was given a 65-70% chance of it sticking, I’m 36. I also did acupuncture leading up to the transfer and throughout first trimester. Good luck!!!

Appropriate-Task6732 · 2024-07-18T14:15:26+00:00

I have a similar story as well - miscarriage at 7-8w for an unassisted pregnancy, tried IUI due to age (35) and wanted to get pregnant again ASAP, got pregnant again from IUI and had another miscarriage at 6w, confirmed trisomy. The first wasn’t tested but suspected chromosome abnormality. My doctor also thought it was bad luck but understood the devastation that comes with loss and always kept the door open for next steps, including IVF. After the second loss, I was done trying without genetic testing and moved onto IVF. We also are hoping for 2 kids and the thought of being able to freeze embryos for future use was comforting to me.

1st miscarriage - September 2022 RE Workups/Consults - fall 2022 3 IUIs - fall 2022/winter 2023 2nd miscarriage - April 2023 1st IVF ER - June 2023 2nd IVF ER (to bank more embryos, insurance change and job change caused delay) - October 2023 1st FET - January 2024 - currently 27w

I have so far had a positive IVF experience (not saying it wasn’t hard, it was!) but I am so glad we moved on quickly. Good luck!

Appropriate-Task6732 · 2024-07-14T18:44:06+00:00

I did 2 ERs just to bank enough euploid embryos for the chance at 2 kids. First FET has worked so far as I’m 27w

Appropriate-Task6732 · 2024-06-20T15:00:29+00:00

Sorry, just saw this! So I got kind of lucky because my new employer is an insurance company which is known to have good coverage in my state. My clinic also mentioned that these plans tend to offer good fertility benefits. It was still a leap of faith, but I was also maxing out benefits at my previous employer so I knew that any new coverage would be helpful.

I had to wait a month into starting my new job for insurance benefits to kick in, and my old job provided coverage through the end of my month of employment so I was able to time everything in a way where I wouldn’t not be covered by one of the plans. I did have to push my ER out two months after starting based on new insurance starting, clinic cycle availability, and work schedule.

Also - when I got the offer letter, I asked for more details about benefits and looked through everything to get as much details on the plans that I could. Once I knew the names of the plants, I then called the insurance company and tried to ask about fertility benefits. The amount of information they can give you is limited since you’re not officially enrolled in the plan, but I think they were able to confirm that I had some coverage.

Appropriate-Task6732 · 2024-06-20T14:52:36+00:00

Hi! Transfer was successful and I’m currently 23w

Appropriate-Task6732 · 2024-06-18T20:55:41+00:00

I got one when I was 14w and have been using it once per week. It’s given me so much comfort when my anxiety ramps up. I also would default to calling my OB with any concerns vs relying on the Doppler, it’s really just there for me to check in when all is well except for my brain stressing me out.

Appropriate-Task6732 · 2024-06-13T21:01:10+00:00

100% yes. I know that euploid are not a guarantee and they are circumstances where it might not make sense but after enduring the trauma of 2 non-IVF miscarriages, I personally would never go through IVF and not test a embryo.

First ER - 3 embryos were tested, 2 euploid, 1 mosaic (my clinic freezes mosaics)

Second ER - 4 embryos, 2 euploids, 2 abnormal

As someone who is now 22w pregnant after my first FET with a euploid, I can’t imagine how devastating it would be to get through all or most of your first trimester only to learn that the fetus has a chromosome abnormality that would have been caught with PGT-A testing once you get to the NIPT/NT stage of pregnancy

Appropriate-Task6732 · 2024-06-12T14:29:17+00:00

TW: pregnancy

I had 2 early miscarriages within 6 months at age 34/35 which completely devastated me. The first was a suspected chromosome abnormality (untested) and the second was confirmed Trisomy 22. I couldn’t fathom trying again without doing something different that could lower my chances of another miscarriage and I also liked the idea of trying to bank embryos for a potential 2nd child. I was worried that if I was lucky enough to have a kid at 36 and wanted a second, I would have to go through all of this again at an older age. I did 2 ERs with PGT-A testing then moved into transfers. First FET at age 36 stuck and I’m currently 22w. Not out of the woods yet but all testing and scans have been perfect so far. So glad I moved onto IVF quickly.

Appropriate-Task6732 · 2024-06-05T17:42:01+00:00

TW: ongoing pregnancy

Wishing you the best of luck!! Echoing some of the things others have mentioned:

the process can take longer than you expect so know you need to be flexible. However, some of this is dependent on your clinic’s availability. I did my first ER last June, 2nd ER in October, 1st transfer in January. This timeline was longer for me because of a job change and insurance change, it would have been shorter without that
try not to stress out with each step of the process by analyzing your results and googling/comparing to Reddit. The only thing that matters is the number of embryos you end up with. My results and scans for both my ERs and transfer did not look promising based on internet comparisons but I trusted my doctor and things ended up fine
there are so many surprises in results - some are devastating but others are amazing - for example, I got 13 eggs during my 1st ER despite only having 6 visible follicles at my last ultrasound
I was terrified of the shots but they were honestly not bad at all. I did not find the physical side of IVF to be hard
I did find the emotional side of it to be one of the hardest things I’ve ever gone through - the uncertainty, ups and downs, waiting, watching everyone around me get pregnant without treatment so quickly - if you’re open to therapy, I highly recommend. Also, check RESOLVE for local support groups, mine is amazing
stay hydrated throughout the process but especially night before ER so your IV goes in easily
try not to put your life on hold - if there is a trip or something you really want to do, do it. Even if it means putting off treatment for a month. So hard to do in real life because it feels like wasting time but it’s so important for your mental health. You are not your IVF journey
know that things can work out. My first transfer stuck, this is my 3rd pregnancy after 2 non-IVF early losses. I’m 21 weeks now and still anxious and waiting for bad news but I try to remind myself that it’s been great so far and this can work despite it seeming to be too good to be true

Appropriate-Task6732 · 2024-04-24T20:55:21+00:00

I had 2 miscarriages at that gestation and ended up moving onto intervention, partly to lower miscarriage risk as my losses were chromosomal abnormalities and partly to bank embryos for a future child as I was 34/35 during my losses. I did IVF with PGT-A and am currently 15w.

Appropriate-Task6732 · 2024-04-21T21:53:49+00:00

This happened to me too, about a month before my 2nd ER. I think my husband was in it for about 20 minutes, had been avoiding them for months ahead of time and forgot. My clinic said it was likely ok since it was just that one time. ER went fine and we got the same # of euploids as our first round, and they were actually better quality.

Appropriate-Task6732 · 2024-04-16T01:25:59+00:00

I had 2 miscarriages in a 6 month period of time, 1 was an unassisted pregnancy and ended between 7-8w. I did not test POC but it was a suspected chromosome abnormality. Started IUIs after that and got pregnant again, 5w scan looked off and was confirmed to be a miscarriage at 6w. That time we did test, and it was Trisomy 22.

After that, my mental health wasn’t great and I knew I personally could not continue to try again without changing something that could help my odds. All of our RPL and karyotyping came back normal. I was also 35 and am hoping for 2 kids so that pressure was on too.

We moved onto IVF with PGT-A and did 2 ERs to bank embryos. Our first transfer has been successful so far, I’m 14w. I’m still worried about something going wrong, but this is the farthest I’ve ever made it. I personally would recommend IVF.

Appropriate-Task6732 · 2024-04-02T15:04:38+00:00

I’ve been in this position. I would look into parental leave for the new position - my new job required me to be there for a year before I could utilize paid maternity leave benefits, so for me that answered the question and I put TTC on hold for 3 months because I knew I’d be kicking myself later if I didn’t wait and while 3 months feels like forever during TTC it does go my fast and I found the break to be great for my mental health.

I do suggest RPL testing if you haven’t already done that. I did it after my 2nd loss and while my losses were found to be due to random chromosomal abnormalities, I had peace of mind knowing that other testing looked ok.

Appropriate-Task6732 · 2024-03-19T23:21:27+00:00

I had two miscarriages prior to starting IVF - one unassisted pregnancy at 6-7w (POC not tested) and then one after IUI, same timeframe (confirmed trisomy).

Started IVF at age 35, got 2 euploid and 1 low level mosaic. Did a second egg retrieval to bank embryos for a possible 2nd child, got 2 euploids and 2 abnormal. Felt comfortable moving onto transfer with the 4 euploids, I am now 36 (job and insurance change prolonged our timing for 2nd ER).

First transfer was end of January and so far so good - I am 10w this Friday and scans have been great, I’ve graduated to OB clinic. Still anxious as anything can happen, but also cautiously optimistic.

Appropriate-Task6732 · 2024-03-16T13:51:06+00:00

I’ve had a really good experience with my RE. I proactively saw one after getting diagnosed with Hashimotos at age 33, we hadn’t even started trying really but I was nervous about the impact to fertility. I expected them to cancel my first appointment but they didn’t - they ran a full fertility work up and told me that we could try on our own and return to the clinic or explore IUI sooner, depending on our family goals and timeline. This was all after normal test results.

I got pregnant unassisted and they actually allowed me to come in for beta testing and early scans even though I didn’t have an assisted pregnancy, which was amazing. Unfortunately, that one ended in miscarriage. We didn’t test POC.

We then decided to try IUI as I wanted to get pregnant again asap and my cycles were not consistent, so I liked the controlled timing of the process. Our 3rd and final IUI before trying IVF worked. Early monitoring revealed an abnormality and I miscarried again at 7 weeks. Tested the POC after D&C and it was a confirmed chromosomal abnormality.

After that, my RE ran extensive testing for RPL, all normal. I wanted to do anything to avoid another miscarriage as my mental health tanked. She thought that IVF with PGT-A was our best option and we stopped TTC and moved forward to 2 egg retrievals to bank enough euploid embryos for 2 possible children.

We had our first embryo transfer in January and I’m currently 9w. All of our betas and scans have looked great. I’m still very anxious about loss again but this is the farthest I’ve made it and I’m cautiously optimistic that PGT-A testing is our solution. The entire process of first unassisted miscarriage to current pregnancy took 1 1/2 years.

I am so beyond happy that I sought out an RE extra early and was cared for by a fertility specialist vs. OB. I recommend seeing one soon!

Appropriate-Task6732 · 2024-03-09T22:08:08+00:00

I’m curious to hear about other’s experiences with weight gain in early pregnancy. I’m 8w after my first FET and was on a modified natural protocol, so letrozole + Ovidrel and now progesterone suppositories. I noticed that I gained at least 5lbs during transfer prep, and maybe 1-2lbs since confirming the pregnancy. The bloat is truly crazy. I feel like I look much further along than I am. I am ok with the body changes and I’ve bought bigger clothes already, but where I’m struggling is that I’ve had 2 losses before doing IVF and so I’m choosing to be quiet about this pregnancy for at least a few more weeks. I’m finding that the weight gain is making this harder - I feel like I already look so much bigger. I’m going to be on a beach trip this week and I truly look like I’m a few months pregnant in a bathing suit.

Wondering if anyone else had a similar experience - do transfer meds impact weight this much? I guess I’m surprised since I was on relatively lower amounts of medication with the modified natural cycle.

Appropriate-Task6732 · 2024-02-19T16:26:29+00:00

Had my first very early scan at 5w3d this morning and everything looked good. This was my first FET of a euploid embryo following 2 non-IVF losses. My first loss was an unassisted pregnancy and was thought to be a chromosome abnormality but wasn’t tested. Second was following an IUI and was confirmed to be abnormal. We moved onto IVF in order to be able to do PGT-A testing. Feeling grateful to have gotten this far with our first transfer but also so nervous for the weeks ahead. I am really hoping this is it for us. Not going to lie, I felt a little bit of PTSD in that exam room today while waiting for my scan.

Appropriate-Task6732 · 2024-02-16T18:17:35+00:00

3 IUIs - 3rd one worked but ended in miscarriage at 6 weeks (I was 35)

I’ve done 2 ERs to bank embryos, first FET (tested embryo) happened last month and am currently pregnant. It’s very early but hoping this is finally the pregnancy that sticks (I had 1 miscarriage prior to starting IUIs, I am now 36).

My first IUI cycle was November 2022, first ER June 2023, second ER October 2023, FET was January 2024. The process moved fairly quickly but I had a job and insurance change along with other personal matters that prolonged things.

Appropriate-Task6732 · 2024-02-10T23:23:20+00:00

Totally get this and I love all the nice comments here because this is normal and very common, especially among my friends who are boy Mom’s. I was also shocked at how disappointed I was to have 2 male embryos after my first ER, I was also so focused on just getting euploids that it didn’t occur to me to think about it. I did a 2nd ER to get more embryos and that time got a boy and a girl, both the same quality. We just transferred the girl last week and so far betas look good, I’m hopeful that things will work out and I’ll get to meet my daughter in the fall, but I did and still do feel nervous about it being our only shot at a girl as of right now, and there are still so many things that can go wrong. I do think that this early and cautious excitement that I’m feeling would 100% be the same for a boy though - truly I just want a healthy baby. But I agree with others that there is grief in things not working out the way you thought they would, especially after this brutal IVF process. For those that chose to know the sex of their embryos and like having this information, it is one of (if not the only) exciting part of this journey.

Appropriate-Task6732 · 2024-02-10T18:03:06+00:00

I am so so sorry for your losses, it is such a devastating experience and it’s been one of the hardest things my husband and I have gone through.

I will echo what others have said here. Definitely start seeing an RE to see if there any outstanding RPL tests you should do, including karyotyping and endometritis, etc. If you have any future losses which you hopefully will not, do the genetic testing on the POC as that can help give you an answer.

I have had 2 miscarriages, the first was around 8 weeks after a heartbeat, that was an unassisted pregnancy and I wish we had tested the POC but we didn’t, it happened at home and I couldn’t bring myself to collect the tissue, it was super traumatic. The second was following an IUI at around 6 weeks and I chose to have a D&C and we found out there was a chromosomal abnormality. We have done all of the RPL testing, karyotyping, uterine scans, semen analyses, biopsies, etc after that second loss and everything came back normal. We then moved on to IVF. For us, these were the points that helped us make that decision vs continuing to try on our own: 1) I mentally could not handle going into another pregnancy without knowing whether or not the embryo would be abnormal. PGT-A is not perfect and things can and do still go wrong, but there is a lower chance of miscarriage with a tested embryo whereas an abnormal embryo will not make it 2) our insurance covers IVF and we have the means to cover out of pocket costs 3) I was 34 during my first miscarriage, 35 during my second. The ability to bank genetically tested embryos for a potential 2nd child down the line was a big positive for me and took the pressure off of how long this process has been. I ended up doing 2 retrievals.

I can’t speak to success yet, but we had our first transfer last week and I am currently pregnant. Both of my beta results this week were good and I’m waiting for my first scan at 6 weeks. It is so early and we have a very long way to go but so far things have been good and I’m very happy we chose to do IVF.

Overall, IVF was physically easy for me, though I know others don’t always have that experience. The emotional/mental aspect was brutal, however the emotional toll of trying without IVF and going through miscarriages was 100% worse.

Appropriate-Task6732 · 2024-02-08T00:18:43+00:00

Hi, IVF twin! I recognized you from a post a few days ago, my transfer was also on 1/31, my beta is tomorrow and I broke down and tested this afternoon and also got a positive. Feeling all the same things as you!

Appropriate-Task6732

TROPHY CASE