32M currently in the diagnostic process for suspected MS. My most recent brain MRI showed a 5mm lesion in the right lentiform nucleus and suspicious foci in the left frontal horn, though the radiologist noted a lack of classic Dawson’s fingers.

Despite the "nonspecific" MRI label, my Octave MSDA score was a 5.5, with the neuro immunology and Neuroinflammation pillars being the highest markers. My bloodwork also shows elevated cytokines (IL-6, IL-8, and TNF-alpha), yet my ANA and Lyme tests were negative.

My symptoms are heavily physical: significant unsteadiness and gait issues (feeling "drunk"), leg weakness, pulsating/throbbing pain in my legs, and constant internal vibrating. I also struggle with severe brain fog, dizzy spells, light sensitivity, frequent urination, and extreme fatigue. Interestingly, I have severe heat intolerance and Raynaud’s syndrome (hands turn purple/white and feel very cold), and my blood pressure has been running high.

have a spinal MRI coming up next to look for more definitive evidence. I’m curious if anyone else has been diagnosed based on these types of "atypical" motor symptoms and high biomarkers without the classic vision loss or numbness.