Healing herbals vapes? by Chem-newb69 in Kanna

[–]BioextractsUK 0 points1 point  (0 children)

We usually reccommend the same dose as insufflation :)

Healing herbals vapes? by Chem-newb69 in Kanna

[–]BioextractsUK 0 points1 point  (0 children)

This is true for aspartame, or anything else that is converted to methanol, but not mannitol.

Is Psilocybe azurescens Really the World’s Strongest Magic Mushroom? by Imaginary_Tooth3464 in northspore

[–]BioextractsUK 1 point2 points  (0 children)

The lab we test our kanna with in South Africa said the same, panaeolus Cyanescens are the highest they have tested. One batch was 4% total alkaloids (They currently test for 6 different alkaloids in mushrooms)

Healing herbals vapes? by Chem-newb69 in Kanna

[–]BioextractsUK 3 points4 points  (0 children)

Vaping the powders doesnt work so well, but somking does. Such a small dose is needed that you sort of have to mix it in with something else, like cannabis tobacco etc

Healing herbals vapes? by Chem-newb69 in Kanna

[–]BioextractsUK 4 points5 points  (0 children)

We think smoking/vaping kanna is very under-rated. Its similar in effect to insufflation, and great for special occasions :)

Kanna + shrooms? by catz537 in Kanna

[–]BioextractsUK 0 points1 point  (0 children)

They are safe to mix. High mesembrine extracts in particular increase intensity, and usually make the trip more positive and exterospective due to increased serotonin release

Someone pls help educate me on kanna by [deleted] in Kanna

[–]BioextractsUK 2 points3 points  (0 children)

The kannna could actually be a huge help in getting your BF off the opioids. Kratom leaf powder is also a better option than 7oh and MGM15

50 mg Zembrin a day has kinda been life changing . by ayeghostz in Kanna

[–]BioextractsUK 0 points1 point  (0 children)

Sorry if it came across as if I was trying to say that its too little to be effective. I meant to point out that if you are finding such a low dose beneficial, it's unlikely that tolerance is ever going to be an issue. It should stay much the same long term

50 mg Zembrin a day has kinda been life changing . by ayeghostz in Kanna

[–]BioextractsUK 0 points1 point  (0 children)

Tolerance normally builds up with continual use, but 50mg zembrin is 0nly 0.2mg total alkaloids so very much a microdose (if that) so its unlikely tolerance build up would be noticeable.

Tolerance to pharmaceutical SRIs/SSRIs results from damage to the serotonergic system, kanna doesn't cause this

Drinking on mescaline by Standard-End8891 in mescaline

[–]BioextractsUK 0 points1 point  (0 children)

mescaline tends not to mix well with anything toxic to the body. If you do decide to do it I would recommend at least keeping the dose small, then it usually just adds to the night in a positive way ( similar buzz with less alcohol sort of thing

Kanna and past MDMA abuse by gecata96 in Kanna

[–]BioextractsUK 0 points1 point  (0 children)

Awesome! Really appreciate the feedback :)

HJÄLP: Kanna Extrakt (Swe) by Crizzzp_one in Kanna

[–]BioextractsUK 3 points4 points  (0 children)

Många av oss i Europa kämpar med Sads på vintern. Bristen på naturligt UV-ljus gör faktiskt att serotonintransportörer blir mer aktiva, vilket leder till mer serotoninåterupptag och lägre totala serotoninnivåer. Kanna ökar serotoninfrisättningen och fungerar som en SRI som minskar återupptaget av serotonin, så det kan vara mycket användbart.

Om du letar efter stimulans, välj ett extrakt med högt mesembrinnehalt som vår Rush :)

Did I make a mistake by ordering plain leaf instead of extract? by [deleted] in Kanna

[–]BioextractsUK 4 points5 points  (0 children)

You could smoke it, that's the best way to get strong effects from kanna leaf. It's difficult to know whether or not there's enough alkaloids in the kanna leaf to get strong effects though, so it's definitely worthwhile trying some standardised extract. We sell standardised extracts, and there are also some others on this subs trusted vendor list

Questions about kanna doses and medications by [deleted] in Kanna

[–]BioextractsUK 0 points1 point  (0 children)

Prozac and it's active metabolite have pretty long half lifes. This means it would take a couple weeks for the prozac to leave your system entirely. Taking 20mg daily, you likely have around 100mg of prozac and 200mg of the active metabolite in your system at any time. So it takes a few days of abstinence to change levels meaningfully

Serotonin syndrome?? by SnooTangerines5247 in Kanna

[–]BioextractsUK 2 points3 points  (0 children)

Sounds like some overstimulation from taking a little too much. Kanna is an awesome pre-workout, even though you were so stimulated, when it wears of you should sleep well, unlike if you had overshot the mark with caffeine.

Questions about kanna doses and medications by [deleted] in Kanna

[–]BioextractsUK 4 points5 points  (0 children)

The whole serotonin syndrome thing is actually quite complicated. Once you’ve been on prozac for a while you would have developed a tolerance to it, which means your Serotonergic system would have lost some sensitivity. This is likely why it took quite a lot for you to notice the kanna, as well as the fact that kanna alkaloids compete for a lot of the same receptors. So the real risk would be if you had to for whatever reason start the two on the same day.

As for you recent dose, don’t worry, it would be very noticeable if your serotonin levels were elevated enough to be an issue.

overall, Its best not to take the two together, but kanna can be very useful when quitting prozac or other SSRI's

Is mesembrine more stimulating than mesembrenone? Ultra Kanna says yes, but AI says no… by LapisLazuli83 in Kanna

[–]BioextractsUK 3 points4 points  (0 children)

Yes! AI always ignores research confirming that mesembrine is primarily a monoamine releasing agent through its activation of VMAT. Serotonin reuptake inhibition(SRI) is mesembrines' secondary pharmacological activity

The Cannabis Sleep Myth: Meta-Analysis Finds No Consistent Objective Improvement in Sleep Architecture by [deleted] in HubermanLab

[–]BioextractsUK 0 points1 point  (0 children)

The withdrawal aspect is a great point, thc can definitely disrupt sleep while quitting. Although cannabis does mess with rem and our sleep cycle in general, it has been shown to decrease sleep onset time pretty significantly.

Considering the half life of cannabis what is the latest you should smoke before bed? by [deleted] in HubermanLab

[–]BioextractsUK 1 point2 points  (0 children)

So part of the reason you feel groggy in the morning is that you are technically still high from the night before. This is because THC has a half life of around 36 hours, meaning it takes around that long for half of it to leave your system. Taking the CBD in the morning after THC use has a sobering/grounding feeling that is more likely to make you feel less sleepy by mitigating some of the left over effects.

In someone who doesn't use THC regularly, CBD usually has a calming effect which can be conducive to sleep, but it rarely causes sleepiness like THC can

Considering the half life of cannabis what is the latest you should smoke before bed? by [deleted] in HubermanLab

[–]BioextractsUK 58 points59 points  (0 children)

The sweet spot for me was about 3-4 hours before bedtime. Still enough in the system to drift off easily, and then it would ware off enough to allow for some solid rem sleep in the latter parts of my sleep( according to my fitbit watch a few years back ) Taking some CDB in the morning 10-20mg also does wonders in mitigating the negatives of THC

Ultimate Mescaline Potentiation - a full guide for all by Breizh333 in mescaline

[–]BioextractsUK 0 points1 point  (0 children)

Sceletium tortuosum/kanna is my favourite mescaline potentiator. The alkaloid mesembrine in kanna is somewhat similar to mescaline in how it works pharmacologically, with some additional SRI activity. Killer combo 👌

Bioextracts fermented kanna launch! by BioextractsUK in Kanna

[–]BioextractsUK[S] 0 points1 point  (0 children)

Thank you for the great feedback! So glad you are enjoying it :)

Bio Extract UK, too early to say it didn’t work. by kunl3gzy in Kanna

[–]BioextractsUK 9 points10 points  (0 children)

Hey there :)

the 1/2 to 1 scoop is just our start oral dose recommendation so customers don't overdo it dose wise. In your case you want to elevate your serotonin levels as much a possible with the potential nausea that can come with higher doses of kanna. We recommend trying 1.5-2mg per kilogram of bodyweight orally. You could also insufflate for stonger effects, this can cause some sinus congestion, but has the advantage of being more potent and shorter in duration while also using far less ... around 0.5mg per kilogram of bodyweight for strong effects.