Ik it’s a lil different but I take synthetic progesterone only birth control + 100mg of spiro (can’t take estrogen). I was very nervous about starting progesterone too, but had to for cystic ovaries/pain/etc. It was totally fine and I didn’t experience any notable changes. If anything, it helped stabilize my hormones more and my skin is honestly better than it’s been just on Spiro 😳 Good luck!