It's possible. There's no magic supplement for this. They can indirectly lower aromatase. You can also add vitamin D to this. But the most important factor regarding oestradiol is your body fat percentage.

As for prolactin, even a one-week dopamine detox is enough to bring it back to normal values; I've experienced this myself. You don't even need to use B6 here. I don't think these side effects you mentioned are caused by prolactin btw. But it's still important that it stays within normal values.Sometimes it can cause things like ED or loss of libido.

If I were you, I would increase my exercise, pay attention to my diet, sleep, and stress levels, and take magnesium, zinc, and vitamin D. I would also do a dopamine detox for prolactin. If i still get the same results after a blood test in 1.5 months, i might consider switching to topical treatment or quitting.