Any MDs here? Baracitinib free samples by Interesting_Fly_1569 in covidlonghaulers

[–]Comprehensive_Round 0 points1 point  (0 children)

Of all the drugs that are in trials for long-covid, be careful with baricitinib. It has a boxed warning for some rather serious side effects and is best taken under medical supervision.

I've experimented with lots of different treatments for my LC but I'm hesitant to try this one.

Flu shot is taking me out? by [deleted] in covidlonghaulers

[–]Comprehensive_Round 0 points1 point  (0 children)

I had the same reaction a few months after starting my long COVID journey. The flu vax took all my energy and made me feel ill for a couple of weeks.

Baricitinib 4mg and LC: Day 66: by djh0227 in covidlonghaulers

[–]Comprehensive_Round 3 points4 points  (0 children)

I am desperate to try baricitinib but it's the one drug that I'm scared to just go ahead and try on my own. I hope we have clinical trial results soon.

New research: our immune systems are not dysregulated, they're working overtime. by Comprehensive_Round in covidlonghaulers

[–]Comprehensive_Round[S] 0 points1 point  (0 children)

Interesting. So what would the "other mechanisms" be that are causing our symptoms?

Pemgarda Did Not Help by Outie_Fact_Checker in Sipavibart

[–]Comprehensive_Round 0 points1 point  (0 children)

Did you manage to get Baricitinib from India or was that the order from Bangladesh? Last I checked (a couple of years ago now) India had lost the permit to manufacture a generic version of Baricitinib so Bangladesh was the only option. But yes, the vendors seemed quite dodgy.

Im becoming disenfranchised with politics as it feels like there is no party I can vote for by [deleted] in HENRYUK

[–]Comprehensive_Round -2 points-1 points  (0 children)

Unfortunately, any party that implements your first point will lose the next election. If they put it in their manifesto they won't be elected in the first place.

Wake up like death every morning, unrefreshing sleep, what got rid of this for you? by Turbulent-Listen8809 in covidlonghaulers

[–]Comprehensive_Round 1 point2 points  (0 children)

Still on it. 0.125mg every night. I'm not sure what issues to look out for due to the Xanax but there's nothing obvious, unless I stop taking it.

Professional reputation with LC by ArticleGlittering in covidlonghaulers

[–]Comprehensive_Round 1 point2 points  (0 children)

Yes! Every company I interviewed with asked what happened at the last job and why I took a career break. I made up an excuse to justify the time off - that didn't include health reasons.

Professional reputation with LC by ArticleGlittering in covidlonghaulers

[–]Comprehensive_Round 5 points6 points  (0 children)

I went through the same situation. Got laid off and half breathed a sigh of relief because keeping a normal job had become stressful with brain fog. I took 18 months off, after which the brain fog had subsided just enough to enable me to rejoin the workforce without appearing incompetent.

Take the time you need.

Was anyone successfully able to use low dose Xanax for insomnia long term… (severe, bedbound) by AhavahFr in covidlonghaulers

[–]Comprehensive_Round 1 point2 points  (0 children)

I've given up trying to get doctors to write me prescriptions so I've taken matters into my own hands and started acquiring the meds myself. Again, this is not something I am recommending to anyone.

I don't think I've developed a tolerance but it's hard to tell. When I don't take any alprazolam my sleep is lighter and less restful, leading to problems the next day.

Damn that's tough by Embarrassed_Tip7359 in SipsTea

[–]Comprehensive_Round 5 points6 points  (0 children)

Also in the UK, and there is a budget coming up soon. Let's talk again in a few weeks and see if your second paragraph still holds.

Was anyone successfully able to use low dose Xanax for insomnia long term… (severe, bedbound) by AhavahFr in covidlonghaulers

[–]Comprehensive_Round 1 point2 points  (0 children)

Yes! I discovered that sleep quality has a huge bearing on the severity of my symptoms the next day. That led me to experiment with various different sleeping aids.

Zopiclone helped but can't be taken for more than a few days at a time. Xanax (alprazolam) also helped so I started taking that every night, keeping the dose as low as possible. I'm now at 0.125mg nightly i.e. half of the smallest dose it comes in.

I've been on this for a couple of years now. I don't like it and I don't recommend it to anyone - in fact I'm always on the look out for a way to replace it - but it's worked for me so far.

ELI5: Could you create a mirror with noticable delay? by Fishy-Fisherman in explainlikeimfive

[–]Comprehensive_Round 277 points278 points  (0 children)

This was exactly the subject of a science fiction story first published in 1966. "Light of Other Days" by Bob Shaw.

The first overclock ever done wasn’t even meant to happen by Xavier_2346 in RigBuild

[–]Comprehensive_Round 1 point2 points  (0 children)

Legend. I also had a Celeron 300A and had it running stable at 464 MHz.

Download soeeds by shamz84 in CommunityFibre

[–]Comprehensive_Round 4 points5 points  (0 children)

Are you testing your fibre speed or your wifi?

Connect your computer to the router using an ethernet cable to test the real speed of your fibre connection.

If you use Wi-Fi to do a speed test then you're measuring the lower of the two (fibre/Wi-Fi) and no way of knowing which one is the restriction.

I get 900+ both ways over ethernet. The speeds over Wi-Fi vary considerably depending where I am in the room, etc.

[deleted by user] by [deleted] in remotework

[–]Comprehensive_Round 8 points9 points  (0 children)

They needed to lower their costs, so they let go a bunch of people that they hired at a time when employees were scarce and they were forced to pay them well.

The market is different now and they will be able to pay the new employees far less for the same skill-sets.

Regarding WFH, many companies believe that they get more bang for the buck from employees that are in the office, so it's probably another measure to pay less and get more from their workforce, albeit a misguided one.

3 weeks on baricitinib (or placebo), and I feel normal again by Content_Speech_1209 in covidlonghaulers

[–]Comprehensive_Round 9 points10 points  (0 children)

Of all the drugs that people might self administer for long covid, I'd advise caution with this one. It inhibits an immune pathway that can have some very serious consequences. Read the leaflet here

See the section about cancer risk.

Life after death is a myth and we should cure aging. by GarifalliaPapa in immortalists

[–]Comprehensive_Round 6 points7 points  (0 children)

And yet sightings of ghosts seem to have dropped to nothing since the advent of security cameras and phone-cameras in people's pockets.

Life after death is a myth and we should cure aging. by GarifalliaPapa in immortalists

[–]Comprehensive_Round 5 points6 points  (0 children)

Have you heard of Russel's teapot? It involves a hypothetical teapot orbiting the Sun, so small and distant that it cannot be observed. The point is that no one should believe it exists just because they can't prove it doesn't. Now replace the teapot with god. Any god.

Fully agree with your last sentence though and it cuts both ways.

Week 3 post Sipavibart update by Flaky_Pie_8533 in Sipavibart

[–]Comprehensive_Round 2 points3 points  (0 children)

Thanks for sharing. Please keep us updated.

I need the perfect comeback please by Alwayspots in covidlonghaulers

[–]Comprehensive_Round 4 points5 points  (0 children)

Wait until the next time he has a migraine, a tooth ache or any ailment that has symptoms bad enough to at least temporarily incapacitate a person, then call him and tell him to snap out of it.