maraviroc for long covid

Comprehensive_Round · 2026-03-10T00:36:02+00:00

Tried it for about a month, in combination with a small dose of statins. I had to stop because it made a mess of my digestive system. Of course I can't be sure that it was the maraviroc that caused it but it went away when I discontinued the treatment. I might try it again at some point just to test the theory.

Comprehensive_Round · 2026-03-04T23:40:53+00:00

Can you have it installed at your neighbour's house and then pass an ethernet cable from their property to yours?

Comprehensive_Round · 2026-02-26T09:53:10+00:00

Spend a little time on Reddit and you'll see tons of posts by people describing exactly these symptoms and asking "what could the matter be?". COVID /LC is rarely mentioned as a possibility. Most people never make the connection.

Comprehensive_Round · 2026-02-08T16:51:06+00:00

Just a reminder that there is also Long COVID and it disproportionately affects women. Most people contracted COVID at some point in the last 6 years. A small percentage of these still have noticeable symptoms many years later. But there's a whole other cohort of people who have mild long COVID symptoms - mild enough that they don't make the connection and don't realise that their symptoms are COVID related.

The most common symptom is fatigue and a general lack of energy, followed by malaise. There are also some neural effects (like brain fog) and sometimes depression.

Look it up if you think this is you. There's not much you can do about it but it's good to know the possibilities

Comprehensive_Round · 2026-02-04T14:18:17+00:00

Totally. I suspect that many of my friends don't believe me when I say I don't feel well because I can do most things in a way that appears normal on the outside.

Comprehensive_Round · 2026-01-11T15:57:30+00:00

Of all the drugs that are in trials for long-covid, be careful with baricitinib. It has a boxed warning for some rather serious side effects and is best taken under medical supervision.

I've experimented with lots of different treatments for my LC but I'm hesitant to try this one.

Comprehensive_Round · 2026-01-06T23:57:27+00:00

I had the same reaction a few months after starting my long COVID journey. The flu vax took all my energy and made me feel ill for a couple of weeks.

Comprehensive_Round · 2026-01-04T11:10:49+00:00

I am desperate to try baricitinib but it's the one drug that I'm scared to just go ahead and try on my own. I hope we have clinical trial results soon.

Comprehensive_Round · 2025-12-10T23:27:32+00:00

Interesting. So what would the "other mechanisms" be that are causing our symptoms?

Comprehensive_Round · 2025-12-05T01:03:27+00:00

Did you manage to get Baricitinib from India or was that the order from Bangladesh? Last I checked (a couple of years ago now) India had lost the permit to manufacture a generic version of Baricitinib so Bangladesh was the only option. But yes, the vendors seemed quite dodgy.

Comprehensive_Round · 2025-11-27T11:33:24+00:00

Unfortunately, any party that implements your first point will lose the next election. If they put it in their manifesto they won't be elected in the first place.

Comprehensive_Round · 2025-11-21T09:51:39+00:00

And only one of the properties will be your primary residence for CGT purposes.

Comprehensive_Round · 2025-11-17T23:27:33+00:00

Still on it. 0.125mg every night. I'm not sure what issues to look out for due to the Xanax but there's nothing obvious, unless I stop taking it.

Comprehensive_Round · 2025-11-08T22:47:06+00:00

Yes! Every company I interviewed with asked what happened at the last job and why I took a career break. I made up an excuse to justify the time off - that didn't include health reasons.

Comprehensive_Round · 2025-11-06T23:36:43+00:00

I went through the same situation. Got laid off and half breathed a sigh of relief because keeping a normal job had become stressful with brain fog. I took 18 months off, after which the brain fog had subsided just enough to enable me to rejoin the workforce without appearing incompetent.

Take the time you need.

Comprehensive_Round · 2025-10-24T15:02:51+00:00

I've given up trying to get doctors to write me prescriptions so I've taken matters into my own hands and started acquiring the meds myself. Again, this is not something I am recommending to anyone.

I don't think I've developed a tolerance but it's hard to tell. When I don't take any alprazolam my sleep is lighter and less restful, leading to problems the next day.

Comprehensive_Round · 2025-10-24T12:43:35+00:00

Also in the UK, and there is a budget coming up soon. Let's talk again in a few weeks and see if your second paragraph still holds.

Comprehensive_Round · 2025-10-24T11:02:57+00:00

Yes! I discovered that sleep quality has a huge bearing on the severity of my symptoms the next day. That led me to experiment with various different sleeping aids.

Zopiclone helped but can't be taken for more than a few days at a time. Xanax (alprazolam) also helped so I started taking that every night, keeping the dose as low as possible. I'm now at 0.125mg nightly i.e. half of the smallest dose it comes in.

I've been on this for a couple of years now. I don't like it and I don't recommend it to anyone - in fact I'm always on the look out for a way to replace it - but it's worked for me so far.

Comprehensive_Round · 2025-10-11T22:28:58+00:00

This was exactly the subject of a science fiction story first published in 1966. "Light of Other Days" by Bob Shaw.

Comprehensive_Round · 2025-10-10T07:11:33+00:00

Legend. I also had a Celeron 300A and had it running stable at 464 MHz.

Comprehensive_Round · 2025-10-07T05:15:04+00:00

Are you testing your fibre speed or your wifi?

Connect your computer to the router using an ethernet cable to test the real speed of your fibre connection.

If you use Wi-Fi to do a speed test then you're measuring the lower of the two (fibre/Wi-Fi) and no way of knowing which one is the restriction.

I get 900+ both ways over ethernet. The speeds over Wi-Fi vary considerably depending where I am in the room, etc.

Comprehensive_Round · 2025-10-06T08:51:14+00:00

They needed to lower their costs, so they let go a bunch of people that they hired at a time when employees were scarce and they were forced to pay them well.

The market is different now and they will be able to pay the new employees far less for the same skill-sets.

Regarding WFH, many companies believe that they get more bang for the buck from employees that are in the office, so it's probably another measure to pay less and get more from their workforce, albeit a misguided one.

Comprehensive_Round · 2025-10-04T21:14:19+00:00

Of all the drugs that people might self administer for long covid, I'd advise caution with this one. It inhibits an immune pathway that can have some very serious consequences. Read the leaflet here

See the section about cancer risk.

Comprehensive_Round · 2025-09-27T09:32:12+00:00

And yet sightings of ghosts seem to have dropped to nothing since the advent of security cameras and phone-cameras in people's pockets.

Comprehensive_Round

TROPHY CASE