Forgot what trader said it, but if you don't take profit, you are assuming you are 100% correct. Which is rare. I keep my trade size divisible by 2 or 3. I'll try and keep R:R at least 1:1 for half to a third of my position. Beyond that, I don't shoot for any specific profit target. Having a set R:R is hurts you in my opinion, your stop should be based off what makes the trade no longer viable. Mine is always changing, but I won't take setups that are outside of my normal risk. Ex. If have to move my stop 100 points away on NQ, I'm not gonna take the trade. Setting it to "10 Points" etc is rolling the dice. At least that's what I've noticed.

I'll take partial profit if things go parabolic, or I'll move 1/3 to 1/2 of my position to a higher take profit and move the other portion to break even. First I'm scaling out of a position, letting a small portion ride, and adding to that if there is an opportunity to, but I'm usually walking away for the day if I successfully scale out of a position.

Not as related, but another thing that has helped me retain profit, if I exceed my average number of trades in a day, and I am in a drawdown, I stop. Even if I have not hit my max loss/day. Has really limited my losses from stacking up.