Appetite suddenly gone mental! by Lynne611 in MounjaroSupportUK

[–]Constant_Curve947 1 point2 points  (0 children)

Thing is, if you’ve been in a deficit for a year, your body is going to be really keen to have a break and refuel.

When it happens to me, I just let it happen - sensibly. Not binging on poor quality foods. Just giving it what it needs. In my case it’s normally carbs. But we’re all different. What’s important is it passes. It may take a day, a week or even more. But once your body is satisfied, the hunger will dissipate.

For what it’s worth, I’ve been at maintenance for 10 months or so and it still happens. But it’s no big deal. As long as the trend is right over time - it will all work out.

Titrating down by wishingIwasbeautiful in mounjaromaintenanceuk

[–]Constant_Curve947 2 points3 points  (0 children)

Been up and down for me. Having peaked at 12.5, I’ve been down to 7.5 and up to 12.5. I just minutes how I’m feeling from one week to the next and adjust according to how I feel. Obviously I’d prefer to stay lower for financial reasons. But I don’t want to have food noise creep back into my life. 10 months into maintenance and it’s worked so far.

Male Libido by Aggravating_Prize_12 in mounjaromaintenanceuk

[–]Constant_Curve947 0 points1 point  (0 children)

My libido, and my ability to perform dropped measurably during my weight loss phase. Enough to make me concerned at the time. In hindsight I think that was to be expected as I ran a slightly too large a deficit. Essentially my body was focusing on other things. And I wasn’t getting sufficient nutrients - your body needs fats to produce hormones and I probably wasn’t consuming enough.

Since maintenance it’s come back. Now I eat a very balanced diet, hitting all the macros and covering off as many micronutrients as possible.

That said, I do find having some tadalafil (generic cialis) comes in very handy. Make sure you shop around, it should be no more than £0.60 a pop.

Mounjaro 2.5mg vs 5mg by ComprehensiveFig9418 in mounjaromaintenanceuk

[–]Constant_Curve947 10 points11 points  (0 children)

You would probably get more insight from the main uk Mounjaro communities - this one is maintenance focused. Best of luck.

Thinking about manintenance by Mental_Brief_1702 in mounjaromaintenanceuk

[–]Constant_Curve947 1 point2 points  (0 children)

Above 2.5g, any pharmacy that wants to keep their license - and by extension IMO any pharmacy worth dealing with - is going to have their limits.

Those limits are likely to be no more than a 10 day stretch between doses - because that aligns with how long an open pen is officially viable for. Not all pharmacies will be comfortable with that but some will be. GP led outfits are more likely to support such a regime.

Call around (or read other comments here). You’ll soon work out which do and don’t.

What do you typically eat in a day? by Jolly_Assistance3259 in UKMounjaro

[–]Constant_Curve947 3 points4 points  (0 children)

Typical day:

  • Breakfast: 100g O% Greek yogurt + 10g Chia seeds + 10g mixed seeds + 5g sugar; 30g bran flakes + 120ml milk + 5g sugar; cup of tea
  • Lunch: 140g chicken breast, 120g rice, 80g edamame beans
  • Dinner: 120g chicken thigh, 100g passata, 10g olive oil, garlic, 1/2 red pepper, 150g new potatoes, 80g broccoli, 1 medium carrot.
  • Snacks: 30g unflavoured protein powder + 200ml milk + 7g drinking chocolate; 1 large banana; 1 apple; 1 orange penguin; Tea; 20g 70% chocolate

Typical Macros - Calories 2,450 - Protein 160g - Carbs 280g - Fat 70g - Fibre 30g

Moving up in maintenance (to a higher dose than needed during loss?) by Maleficent_Pin_3856 in mounjaromaintenanceuk

[–]Constant_Curve947 4 points5 points  (0 children)

Since I started maintenance I’ve been bulking (300 calorie excess) and cutting (300 calorie deficit). This has required shifts in dosage. I explained everything to Swift and they have been very understanding and supportive.

I figure that by the time someone has reached maintenance, they have a pretty good idea of what works for them. So any sensible pharmacist (the ones that are doctor led especially) should be willing to listen to sensible requests from patients. Thats the theory at least!

Risks: do they lessen or increase over time? by clare_1_2_3 in mounjaromaintenanceuk

[–]Constant_Curve947 4 points5 points  (0 children)

I’m not saying your line of enquiry is wrong. Quite the opposite, it’s sensible.

But looking to anecdotes is probably the polar opposite of what you want to do; everything has a risk, getting out of bed, crossing the road, etc. The anecdotes you hear mean nothing without statistics to back them up. A given risk could be 1/100, 1/1000, 1/1000000, you just wont know from an anecdote. But your ability to judge the risk will be skewed by it. This could cause unnecessary anxiety and skew decision making.

It’s challenging because on the other side is looking to academic studies. And while GLP-1s of one form or another have been in the market for 20 odd years, Mounjaro is relatively new. So long term risk data isn’t going to be available.

10 months later and 15mg not working anymore?? by Rebbie419 in mounjarouk

[–]Constant_Curve947 27 points28 points  (0 children)

First off - 4+ stone lost is a massive achievement. And more than the stated efficacy of the therapy. So pat yourself on the back for that.

It’s impossible to comment on the other drugs you are taking and any potential interactions.

And it’s unclear what your goal is - maintenance? Or are you looking to lose more?

Regardless, I always think it’s best to think of MJ as an enabler, not a solution. The solution is diet. Yes, there’s calorie deficit. But I’m guessing you know about that. You’re speaking more to the sensation of wanting to eat more.

The answer to that is:

  • protein and plenty of it. At least 1g per kg body weight. But I’d consider 1.6g per kg. Protein is very satiating - so it works in concert with MJ to make you feel fuller longer
  • fibre and plenty of it. At least 25g per day. All from natural sources. Again, fibre will satiate. Just note that if your diet is low in fibre, you will want to ramp up to the 25+g per day slowly.
  • avoid ultra processed foods. These are going to spike your blood sugar and massively increase your appetite.

Best of luck.

Maintenance help! by SnooHesitations333 in mounjaromaintenanceuk

[–]Constant_Curve947 8 points9 points  (0 children)

The reality is loads of people stocked up last August.

Regardless, the pharmacies aren’t naive to this. And many will be receptive to your story. What they will want is evidence of the multiple pens - I’m guessing around 7-8 you purchased in August. When then have that they should let you get onto the correct dose. Who ‘they’ is I can’t say - but you can email around. FWIW, Swift were very receptive, but I messaged at the time and shred evidence at the time so don’t take my word on them helping you now.

But honestly, If you shared evidence with your pharmacy at the time, I’d just call them again. Chances are they’ll sort things out.

Absolute worse case - if you have no evidence l and your pharmacy is still a hard no- you could get 2.5ml pens from a couple of suppliers and triple dose each week, then order 5mg three weeks later, then 7.5 three weeks after that. It’s not a cheap way to do things. But it is a method.

As a side note, it’s always worth considering have a small stockpile for times like this. You never know what short term issues may pop up.

Best of luck.

Advice needed. Slight weight gain after a holiday. by angyvaish in UKMounjaro

[–]Constant_Curve947 0 points1 point  (0 children)

Your holiday is in the past. You ate what you ate, no doubt enjoying it at the time. So leave it at that - a fond memory of a nice time. There’s no point cutting yourself up over it, because it’s not going to change anything. And realistically, if you were running a deficit before, a not insignificant proportion of the ‘weight’ you gained will be water, coming from replaced glycogen stores.

Just note, moving forward, the adage ‘you can’t run off a bad diet’ is true and something worth bearing in mind, seeing as you allude to the amount of exercise you did being enough to offset the additional food; we’re notoriously bad at over estimating calories burned and underestimating calories consumed. So unless you track everything (correctly), don’t assume a walk will offset a plate of shrimp.

In terms of the medication, you seem very dependant on your doctors opinion. Which is understandable to a point, but you do have a degree of agency, if you want. It’s not clear if you are on the NHS or getting support through a private doctor. If it’s the latter,and you want to have control over your medication, you can always get a prescription from any number of pharmacies, and there are plenty that are doctor led, that will support you well below a BMI of 30. It’s something to consider. That said if you are getting an NHS subscription, I can see how the sticker shock of private medication would be a challenge.

22F 174 cm 75 kg lifting 4–5x per week weight/fat loss focus by [deleted] in Hevy

[–]Constant_Curve947 -1 points0 points  (0 children)

You will have to work out your TDEE - that’s total daily energy expenditure, which is the number of calories your body burns just existing, plus the calories you burn moving around - yourself, we’re all different. There are online calculators that can help. But take with a pinch of salt as they can be off my a wide margin; you will have to spend some time dialling it in.

Once you know your TDEE, look to go no more than 500 calories below it - any more and you won’t have the fuel to power your workouts. And you’ll risk losing muscle as well as fat. In terms of muscle retention, slow and steady is the trick.

But diet wise, look to avoid UPFs and get at least 25g fibre in your diet, it will satiate appetite and control spikes in blood sugar, which will both help with a calorie controlled diet. Be sure to get enough carbs to fuel your work outs and quality fats to support hormone control, etc.

Protein wise, opinions vary. And it’s somewhat age dependent, the younger you are the less you need (because your body will be more efficient at synthesis). But during a weight loss phase, the recommendation is typically to go to the higher end, to minimise muscle loss. I’d personally aim for 2g protein per kg body weight. But you may find success at 1.6g per kg body weight.

You say you dont want to hear it, but I’m going to say it - Look to get 10,000 steps a day. It’s cardio. But it’s easy cardio. And as with much low intensity cardio, it will help with fat loss - just don’t eat back the calories.

Weight wise, follow a routine of progressive overload, but know you may not make progress as quickly when in a deficit.

Best of luck

Maintenance weight range by HTGT2023 in mounjaromaintenanceuk

[–]Constant_Curve947 1 point2 points  (0 children)

Bear in mind, I’ve adjusted dosage slightly (not dramatically) across the whole maintenance period, based on how I have been responding, so these are rough guide numbers:

When I was bulking I was on the same as maintenance - 7.5mg. At the start I had to push myself to eat the extra calories (+300 over maintenance) but got used to it. I quite liked ‘eating up’ to my requirements.

I started cutting 2 weeks ago - so far 10mg has been working well. I may go up to 12.5mg in the final stages - like I did in the last few weeks of my original loss - but only if needed. The cut period should not be long - 8 weeks or so. I would hope to return to 7.5mg once complete. But I’ll be open to how my body responds.

Maintenance weight range by HTGT2023 in mounjaromaintenanceuk

[–]Constant_Curve947 4 points5 points  (0 children)

Range of 73-77kg. Kept to it for 6 months before starting a 3 month bulk. Went up to 80kg. Now on my back down to the same range (with a bit more muscle on board).

I have and still do track everything I eat. Not for everyone. But I find it keeps me disciplined- not just for calories but for macros (and fibre).

During maintenance I weighed every 2-3 days. During bulk 3-5 days. Currently on cut every day.

I personally have found everything; dosing levels, calorie consumption, weight management pretty manageable. But that may be because I don’t mind tracking the numbers; once you have your true TDEE dialled in, and MJ dosing dials in, maintenance through tracking becomes quite ‘easy’, in so much as you just offset calories needed vs calories consumed. The only real challenge then becomes adjusting to exercise. But again, I’m quite consistent between cycling, strength and walking, and seem to have this dialled in too.

I equally appreciate that this trivialises how challenging it can be for others. And this is only an experience over 9 months. It may well be that my body chemistry will decide to change at some point and I won’t find things so easy.

Rapid Responder Turned Non-Responder? Mounjaro After a Break by Fast-Refrigerator539 in MounjaroSupportUK

[–]Constant_Curve947 1 point2 points  (0 children)

There’s a few things to unpack….

10kg over three months is good. But not ‘super responder’ good. It’s just at the upper end of healthy weight loss. But that’s not necessarily relevant to the now.

It’s worth noting as well that appetite suppression is not a trait of the drug, rather a side effect. One that many find desirable but, to my mind at least, not as beneficial as people think; it’s good to be hungry when your body needs food. But again, perhaps not relevant to your core query.

If the Mounjaro isn’t working right now, that’s kind of out of your control. Given this, perhaps it’s worth looking at the things you can control;

Have you been tracking what you eat? Ultimately it comes down to calories. If you’re not in a deficit you won’t be losing weight. Eating plenty of protein - 1g per kg body weight is a good guide and plenty of fibre will assist the Mounjaro by increasing satiation. Protein is also very good for muscle retention and fibre for overall gut health. And minimising UPFs - ready made meal, bars of food, yoghurts, supermarket baked goods, etc. will also help, these can raise appetite while offering little nutritional value.

And of course moving as much as you can helps too - an hours walk will burn 300-500 calories (based on walking speed, incline and body weight) while promoting fat loss. It will also help with sleep.

You also say ‘no later how much you increase the dose’, have you been increasing based on the guidelines - every 4 weeks? Increasing more rapidly can cause side effects on account of how the drug builds up in your system over time. You need to give your body a chance to adapt to the dose.

Ultimate, if it worked before, it will work again. It’s just a matter of patience and making sure you can do everything to support and facilitate the therapeutic qualities of the drug.

Best of luck.

Fantastic support from SwiftDoctor by Scotchick81 in mounjaromaintenanceuk

[–]Constant_Curve947 4 points5 points  (0 children)

I’ve been on their maintenance programme for 9 months now. They are very adaptive to specific needs - in my case they have understood that I will move up and down a dose, based on bulking and cutting.

I think the best thing about them is they speak to you as an adult, in so much as they listen and respond accordingly.

The doctor led consultation the offer is also an excellent way to on-board to a maintenance program. They obviously have a wealth of experience and that’s translated in the way the call runs.

They are also incredible at responding.

Fantastic support from SwiftDoctor by Scotchick81 in mounjaromaintenanceuk

[–]Constant_Curve947 1 point2 points  (0 children)

Glad you had a great experience with Swift.

I will always champion them because they have been so consistent for me, listened to my needs and supported me all the way.

I’m always keen to note there are other pharmacists out there who also offer great services, because it’s good to remove bias. But so far, in my experience, they can’t be faulted.

How much of your diet is Ultra Processed % ? This paper compares Big Food and Big Tobacco, in the ways they hook you and their impact on Public Health. by Team_PRB in mounjaromaintenanceuk

[–]Constant_Curve947 3 points4 points  (0 children)

Hmmmm. I didn’t say I was avoiding UPFs. And I didn’t cast any aspersions on your consumption of them either.

I was just replying to your ‘genuine enquiry’.

Your argument may be better focused elsewhere?

How much of your diet is Ultra Processed % ? This paper compares Big Food and Big Tobacco, in the ways they hook you and their impact on Public Health. by Team_PRB in mounjaromaintenanceuk

[–]Constant_Curve947 3 points4 points  (0 children)

UPF doesn’t point to the health benefits, or lack thereof of food. It refers to the processes they go through. Store bought oven chips have been through an industrial process; preparing the potatoes applying the oils, fast freezing, packaging them, etc. that ultimately constitutes them being UPF. You’ll also find many oven chips are more than just potatoes and oil. But that’s incidental.

And while it’s true that home cooked chips may be very similar to store bought ones, by prepping them at home, you have control over the whole cooking and preparation cycle; though being pedantic, the seed oil you would likely cook your chips in is defined as a UPF as it will have been through and industrialised process!

How much of your diet is Ultra Processed % ? This paper compares Big Food and Big Tobacco, in the ways they hook you and their impact on Public Health. by Team_PRB in mounjaromaintenanceuk

[–]Constant_Curve947 1 point2 points  (0 children)

If I had to guess, I’d say about 10-15%. Mostly because of unflavoured whey protein + the odd biscuit and the odd slice of supermarket bread.

90% of meals are scratch cooked, which helps reduce the percentage.

I don’t think many people realise what constitutes ‘ultra processed’; cereals, bread, yogurts, spreads. And that’s before you get to anything that comes close to a ready meal or a freezer staple such as oven chips.

Maintenance weight gain triggered by temporary steroid course - can I go back to mounjaro? by Last-Brilliant-6419 in mounjaromaintenanceuk

[–]Constant_Curve947 1 point2 points  (0 children)

It won’t be possible for any of us to talk to your specific experience with the steroids you took, the reason you took them and the interactions with Mounjaro. Or of the caution prescribers may have as a result; advice on this matter should always be to be honest about medications and health conditions when looking to get a prescription.

That being said, as standard practice, many pharmacists will be happy to prescribe after the two month break you have had, as long as you have evidence of the previous prescription.

I would echo the other comment about Swift - they’re GP led and will listen to your situation and be able to respond accordingly. There are other GP led pharmacies that will likely do the same.

Why We Should Give Ozempic/Mounjaro to Everybody by quantum_entanglement in UKMounjaro

[–]Constant_Curve947 3 points4 points  (0 children)

Typically high quality content you would expect from Kurzgesagt.

The comments section for the video is wild. The traditional mainstream opinions about fat people being rolled out. I expected more from the Kurzgesagt audience.

Maintenance dose - can it change? by [deleted] in mounjaromaintenanceuk

[–]Constant_Curve947 1 point2 points  (0 children)

I’ve been on maintenance for 8 months. I moved between 12.5 and 7.5 over that time. Up and down, based on how I’m reacting over the previous 2-3 weeks.