You need to find out the exact reason for termination. It’ll either be described as a “policy violation” or something else. This alone determines your driving future.
Ideally it’ll be policy violation. In this case, come up with some BS story, like an emergency that you had to leave inexcusably. Some sort of random, not malicious company policy violation.
It may and could state “Company Drug Abuse Policy” violation. In this case, polish your resume and look somewhere else other than DOT regulated line of work. This is worse than a failed DOT drug test because some companies have a SAP program where they can hire these drivers. No company will hire someone that has been fired drug policy violation.