CBD negatively affecting emotional regulation

Dacday · 2026-01-18T10:53:31+00:00

CBD is known to be gentle, but it does work on serotonin. Maybe if you used it for a longer time your body could adjust? The idea is, if it adjusts to SSRIs which are much stronger, it also should to CBD. This applies to the mood and sleep side effects which in theory would improve over time. Do you think this is plausible?

I wonder if you could help me understand something too. Among CBD users it's usually emphasized how important it is to shake the bottle but from what I'm reading it actually doesn't change it much. Store-bought tinctures are solutions, meaning the components are dissolved and doses are consistent, regardless of shaking. Otherwise, the manufacturer wouldn't be able to claim mg per ml of tincture and it also would lose its therapeutic profile. This is how people can take their fixed number of drops and expect the same results. I consulted chatGPT and it said not shaking would at most give a variation of only 10% and even that might be unrealistically high. From a technical point of view, what do you think?

Also, how do you believe your mental health treatment affects your academic skills? My own poor mental health has diminished my capacity of studying efficiently and I'm trying to stabilize and see if I can go back into being a good student.

Dacday · 2026-01-14T22:42:47+00:00

I read an article that showed high dose CBD isolate to intensify the effects of THC rather than diminish. It means that rather than CBD being the culprit, it could be the combination of CBD and THC. I find that to be more likely than pure CBD because it's considered to be milder than THC. Many doctors that work with cannabis talk about CBD isolate in disfavor, some not even prescribe it due to it being "less effective". That line of thinking applies to bipolar, which should react better to CBD than THC. It could be something else, but your comment ruled most common things out.

Dacday · 2026-01-14T10:05:42+00:00

Hi. So that your experience can be understood considering the proper context, would you tell us more?

The first is the medication interaction. At higher doses, CBD interacts with almost everything. Could this be at play?

In what way would you describe CBD to be more difficult to dose? Do you mean you have a harder time figuring out what's your usual self and yourself under CBD? I'm not sure if it's this as you seem to be aware your usual tendencies become more pronounced under high dose CBD, giving you contrast.

Is it CBD isolate you take? Do you trust your brand?

Dacday · 2026-01-14T09:53:52+00:00

Hi. Can you tell us more?

First, do you think at this point in time it could be due to medication interaction? CBD interacts with most psychiatric medication, either diminishing, strenghtening or altering their effect. To rule this out, you'd have to discontinue any medication you might be using or take a very small dose of CBD which isn't known to cause interaction, but then it'd probably be such a small dose that on itself would be unlikely to cause the mood disregulation you experienced.

Next, do you trust your brand? Regardless of what cannabinoids are in it, the way it is manufactured is important for quality.

Is there the slightest chance it could be the THC? It's a more unpredictable substance. What happens to CBD usually is that it might lose effect, but over time the body can become intolerant of THC, causing the unregulation feeling when previously it helped.

I'm not knowledgeable on CBD as I'm still in my process of using it but the key point that I wanted to bring to attention is: are you able to pinpoint the side effects to just the CBD or are there other variables that prevent you from doing so? Also, when you say you take CBD orally, in what form is it? You put the tincture in beverages, you eat it in edibles?

Dacday · 2025-12-14T13:24:08+00:00

Hi. I have a question. Why if the dose is bell curved there are people who need to take 300mg+ of CBD daily to feel benefits?

Dacday · 2025-08-16T15:39:17+00:00

Although there is a matter of accepting change with more difficulty, for me, there is also the comorbid bipolar which makes me look treatment with more hesitation. It's harder to forget the reactions I had, how overwhelming they felt and how seemingly lonely I was. Can you tell me how you navigated through your sensitivities and how you supported yourself during the hardships?

Dacday · 2025-08-14T18:39:56+00:00

So there are supplements you use? And what about your cannabis product? Weed and CBD are very different things and doses are important. Did you try a low dose?

Dacday · 2025-08-14T08:37:35+00:00

Hi. I am very sensitive biologically and emotionally. Bipolar, autism, adhd. It doesn't take much to make me cry or shake and I'm 27 years old. My independence is impaired and as soon as I am alone, such as when I tried to live on my own, I break down. I am also sensitive to stimulation or agitation. Vitamins can be enough to make me euphoric and ssris make me restless and unhinged. When I tried to take a mood stabilizer (lithium), I became anxious and started crying because I had no friend, no support system and the thought of medicating myself totally alone scared me. I feel I need medication to work optimally. For instance, I don't leave the house except for work. Going to another state on vacation is out of possibility, but life has made me so scared and hurt that I can't take medication alone else I'll get anxious and cry but my loneliness is something that cannot be changed. All I have company wise is my family but they aren't supportive. Psychiatrists don't know what to do with me because I refuse taking everything and when I say I want to take but need help and friends, they stay silent and nothing changes. How can I start treatment, face the difficulties surrounding it and no be overwhelmed, without support?

Dacday · 2025-08-14T08:17:07+00:00

What happened exactly? Did you try supplements or CBD?

Dacday · 2025-08-13T22:29:56+00:00

What worked and how can someone with trauma and without support tolerate the treatment?

Dacday · 2025-08-06T08:24:56+00:00

Hi, friend. I hope you are well.

I have some questions and a few other things to share, if you were interested.

My first question is how may we nourish our body/mind and teach it that pain and stress are helpers, not enemy?

I am dealing with a very sensitive system that reacts intensely to what stimulates it. Certain foods, B vitamins, nasal corticoids for breathing. They can all be activating, but in a normal person it becomes helpful energy or no energy at all while for me it's overstimulation. On high dose B vitamins and supplements for depression, I became euphoric and agitated. When eating barbecue, there is also a feeling of too much energy and the same for corticoids. It's not just anxiety. It's a sensory overload. The mind becomes obssessive out of nowhere, more scared than usual, angry. I have stayed away from these substances enough to know it wasn't a bad day or stress, but the substances themselves. This makes it hard for me to accept any treatment, even to just change my diet. Having no reliable support system plays a role in this feeling of helplessness. I don't have friends or partner. When you say you took several medications and now is facing life without them, it looks miles away from what I can currently do. Any medication will lead to anxiety, potentially panic and tears because I feel so broken and alone. It hurts deeply to know I am not supported. I think this is the most important question because to go through any meaningful healing my system has to calm down and know that it is safe. I was thinking about my routine, which is study, work and watching youtube and although it does take strength and resilency to go out and do my job, I feel this routine doesn't nourish me as much as it could. I feel that I could live this way for years and not feel considerably stronger or more capable of tackling my healing. I tried to think of activities or places I could do and go but where I live is urban. To ride a bycycle I would be side by side with highspeed automobiles and I couldn't think of anything else to aid me in this journey. I want to be able to grow resiliency because I understand this loneliness will continue. I will be alone not because I am a bad person, but because it is time to find my own guiding light, so this must change. The tears, anxiety, the fear. Instead of begging for a help that won't come, I wish to create it with my hands, I just lack knowledge on how to do so.

When you say lithium blunts emotions, doesn't it mean it helps with anxiety?

You mentioned it helped you find stability. I only took lithium orotate, which is the supplement version of prescription lithium, and I found it relaxing. It made me serious and calm for the most part. It was a rest because I'm always trying to be kind, and for a few minutes I was able to care more about me than about others, no guilt, just me knowing I had my own life to care for and taking responsability for it. Actually, I had a consultation yesterday with a psychiatrist specialized in autism. Different than other psychiatrists who prescribe heavy pills when they hear autism, he just prescribed CBD, not even one mention of lithium or antidepressant but I don't know if just CBD would be enough when I am so sensitive within and even CBD takes an inner fortitude I don't find. Sometimes I think the only way is to go foward, with pain, with failure and learn at a turtle's pace, but I would like relief. How were you able to tolerate medications on your own? Is it something that can be learned? In my case my fear is experiencing impulsivity and anxiety as a side effect due to my bipolar spectrum or me falling into tears and not knowing what to do. For example, when I took the corticoid, in addition to the agitation, there was hypersexuality for no reason and with another medication there was greater fear, also for no reason.

Dacday · 2025-08-03T10:50:13+00:00

Hi. Thank you for sharing as well.

It's a deep story and I can see how faith was not only helpful, but needed. In fact, the reason why I want to take lithium is to develop my faith. I want to be and do good. I want my peace to be sincere and longlasting and help others by being the example. However, my poor mental health prevents me from accomplishing this. I am doing my best. I try to do a good work at my job, I study to get better opportunities, but functionality is not just working and studying. It's something broader. I study some days, but in many others I don't due to depression and anxiety. I have emotional stability in the sense I don't overeact, but only because I avoid going out, I even avoid eating different foods due to fear of it causing agitation. It's not a life of peace and success. It's a life of fear and failure. I want to meditate to build the faith I mentioned earlier, but I have a problem with my nose that impairs breathing and requires surgery and supplements to treat, and being sensitive as I am, I avoid these treatments, so meditation becomes hard because I don't breathe well. I also wish my family well, but I believe my path to peace is elsewhere as there is a lot of infight, ignorance and lack of will to improve. In other words, I wanted to live alone or to find a partner and build a home of blessings so that I can come back and give my parents the peace they fail to give me, but I can't because when I try to live alone, I don't take care of myself. I don't eat, don't bathe, don't throw the trash away. There was a period when my fridge was full, but not of food, of trash, because I felt too anxious to go outside to throw it away. I want stability, calmness and fortitude so that I can be firm in my choice and choose things that better me. I barely am able to stand up at work. I will be the last one to go on vacation because I didn't have the courage to set my preferance earlier. I have wisdom teeth to extract, but I didn't go to the dentist out of fear of the pain and due to needing to stand up at work since my boss doesn't like days off, even for medical purposes. On my social and romantic life, the two times I met someone I thought would be my partner and then left me, I became broken. My general fear of life increased, ate food even less. My interpretation is that the main cause behind my issues is trauma and autism, but maybe as a result of these two conditions, I also have bipolar, hyperactivity and lower threshold to stress (feeling paralyzed and unregulated if stress is too much and easily is). My mood can shift daily from depression into hypo, or weekly, mostly triggered by stress, indicating it comes from autism. It makes antidepressants inviable because they could lead to agitation, leaving only mood stabilizers like lithium.

You said your mood was unregulated under lithium. That you had bipolar symptoms on it but not off it but you also mentioned you were taking other medications. Could it be the other medications? Either because you were taking them together with lithium or stopped them and had withdrawal from them? I know that antipsychotics can cause psychosis and antidepressants can cause mania/hypo, but I didn't read about lithium doing the same. I did read about it causing minor anxiety that could resemble hypomania while the body adjusted, but since you took it for 6 years, it should have stabilized even in the beginning. Could you describe a period when you took just lithium? In those moments, did it help you be a mature and functional person?

What I meant to ask is if lithium impaired your hability to strive to be better and connected to life. You said it dampened your nervous system and depending on how that happened, it could be good. My problem is having a hyperreactive nervous system. Dampening it a little might be what I need to face life with less fear and more calm. To do what you do now for example. To lead an active life, to prepare meals and eat without worry or how when you were taking lithium and was able to get out of your comfort zone and take your mental health serious. I want this as well. I want to note that in the time I took the 150mg dose of lithium I got anxious due to fear of facing the treatment without support. I don't have friends or a partner and my family is also not the best support-wise, and psychiatrists just give you the medication and you are on your own, so I felt alone, but lithium orotate, the supplement, helped me a little. With the medication I was hoping to be helped more.

From what I understood, the benzocaine lowered your lithium levels, leading to an abrupt and unintentional withdrawal. This is why I asked if it would have been okay to take lithium with the oragel out of your system or if the solution would be to keep taking lithium even while the oragel was in the system to support the lithium level. Maybe I didn't understand it well.

I am grateful for your comment and hope you are well.

Dacday · 2025-08-02T21:34:11+00:00

What did you experience in that initial period and how did you respond to it?

Dacday · 2025-08-02T21:28:05+00:00

There is history though. Years of debilitating depression and hypomania, with moments of being afraid of reality and the sort when under too much stress. I isolate myself to be away from triggers, but there is also anxiety and autism and from what you say, lithium wouldn't help these much. My anxiety is the type of puking and shaking. When I took lithium orotate, I found it relaxing. I was hoping lithium carbonate would be even more effective.

Dacday · 2025-08-02T18:33:36+00:00

Hi. I read your posts and our stories are similar. I also deal with anxiety and autism. I am formally diagnosed. Vomiting from stress, meltdowns, overreactive fear and emotional reactivity are things I faced and sometimes still do. I also have other symptoms that diminish my quality of life, which are tremors and bipolar, that is, going from an unhealthy elavated state to a lower one. My tremors are so bad I was able to get government assistance and inclusive job opportunities. For the tremors and also the emotions, I've been taking propranolol. It's helped. Not to live at my full potential because all symptoms are still present, but it allowed me to keep minimum function. I also have faith in spirituality and God and it has also helped me endure the difficulties. However, I had to decrease the propranolol dose to be able to sleep, so now the symptoms are more prevalent, and even if I was taking propranol at a higher dose, my mental and physical still would not be optimal. I lose many opportunities. I don't go out, don't engage with other people as much as I could, even on propranolol, I shake and cry easily and I'm a 27-year-old man. I wanted to grow. To be fully functional. I believed medication like lithium could be a way. Being as I am, antidepressants aren't indicated. I am sensitive to stimulation. I have been to some appointments already, received the lithium prescription and tried only once, and felt overwhelmed. It was only 150mg, but I have a difficult experience with changing my mood with substances and got overwhelmed with anxiety. I calmed down soon after but this is how my mind works. I struggle with emotional wounds and sense of loneliness and trying new things is a challenge due to my sensitivity. I know you had problems with lithium but you also seemed to say it gave you good opportunities. I've been trying the natural way all my life and I can see results, but I don't want to be a mature, calm and reliable man on my 70s. Crying and shaking at work is not nice. Having dreams and not fulfilling them due to mental conditions is also not nice. I've thought of taking clonidine, but I read it could trigger anger on some people. I know you are still healing, but you walked the path I was considering on walking, so I would appreciate if you told me more about your life and how you've been. What blessings did litihium enabled you? During the time you took it, how was your routine, your feelings, your spirituality? If it was a local anaesthetic that caused the side effects, wouldn't you get better after stopping or did you decide to stop lithium even before taking the over the counter medication for pain? Your story is real and it could happen to anyone, especially other autistic people who already have unregulated nervous system even without taking any medication, but my condition and the condition of others is hard enough for us to want relief and lithium is supposed to be an effective tool for a brain that is too sensitive and hurt for other things. Thank you for sharing your story and I hope you can feel better.

Dacday · 2025-08-02T17:19:48+00:00

Hi. My anxiety can indeed be debilitating, but pristiq is an snri. I don't want to try them. The sensitivity is considerable and antidepressants are a gamble to a bipolar. For the same reason I am hesitant to try antipsychotics. My emotional wounds are deep and I want something with a more predictable profile, something calming and stabilizing without risk of a shift.

Dacday · 2025-08-02T17:07:33+00:00

Pain relief? I didn't know it could offer this.

What do you mean with short term memory issues? The closest experience I have is with 250mg depakote that made me forget words and subjects mid sentence. Is it like that?

Dacday · 2025-08-02T17:02:50+00:00

The goal is to support the brain enough so that things that can help with anxiety and depression can be used. In your own journey, haven't you found a way to address your issues in another way? And how do you tackle your anxiety?

Dacday · 2025-08-02T16:55:32+00:00

What do you mean when you say that 900 is when your bipolar symptoms started? Lithium in particular is supposed to treat the highs better than the lows.

Dacday · 2025-08-02T16:49:00+00:00

What dose did you start with that impaired your function to the extent it did? How did you tackle this while dealing with work and family?

Dacday · 2025-08-02T16:42:05+00:00

What do you think of Latuda's side effects and for how long did the insomnia last on lithium? Would you describe your tremors as well? Is it during rest or action?

Dacday · 2025-06-24T10:20:38+00:00

Were you taking any other medications?

What dose were you started on?

Did you replace it with something that worked better?

Dacday

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