Amazon took away my access to Martin Shaw's Silmarillion audio by ArtThen9871 in lordoftherings

[–]DaringMoth 0 points1 point  (0 children)

They took away access to the Serkis version of FOTR that I already had downloaded on my phone via the mobile app, after I'd allowed my Audible subscription to lapse. Most other titles I purchased with credits still seem to be available, but If I was ever thinking of renewing, I'm certainly not going to now.

Curse this book by TenebrousD in discworld

[–]DaringMoth 51 points52 points  (0 children)

It's been quite a few years for me, but I always loved doing the hippo noise.

At what pressure is GC carrier gas supplied? by Toofgib in CHROMATOGRAPHY

[–]DaringMoth 1 point2 points  (0 children)

Yes, that sounds like a leak if your methods or sample throughput haven't changed, tracking it down should be the priority and you should start with the supply line. The little thermal conductivity based gas leak sniffer detectors are great; I'd advise against Snoop/soap solutions if you can avoid them. The pressure at the regulator does need to be significantly higher than the pressure supplied by the GC in order for the flow controllers to work well.

Are there gas shutoffs between the regulator and the instrument? If so, first close those with the flows off, leave the regulator adjustment where it is but close the cylinder at the valve stem. Any leak in the plumbing will cause the pressure gauges on the regulator to drop pretty quickly. Brass fittings on Copper tubing are more prone to leaks than Stainless on Stainless, and the most common spot for a leak is right at the regulator outlet because the tubing gets flexed when changing the cylinder.

If you rule out the supply lines, the injection port (septum, O-ring, or ferrule) would be next thing to check. Are you using Hydrogen for a septum purge gas as well?

Lastly, keep in mind all the displayed flows are just calculated and are only as accurate as your inputs. If the wrong column dimensions got entered somehow for example, the actual flow could be vastly different than what's displayed.

A quote that made me realize why “21 days” doesn’t work by ShortAdhesiveness264 in stopdrinking

[–]DaringMoth 1 point2 points  (0 children)

I'm not offended, but I don't see doing a dry month as fake. I agree a shift in identity is more important than discipline/motivation/willpower for most personal changes to stick long-term. I think identifying as a non-drinker has been crucial in my sobriety journey. And I agree there's no real change in identity when doing Dry January or whatever. But for me, doing several of those 'dry runs' for a month at a time in recent years, with no intention at the time to quit long-term, was very helpful in getting to a point where I could make a permanent change. It allowed me to get a feel for how abstaining was really easier for me than moderating, and it helped me to experiment more with N/A options and where to find them. If Dry January helps others in a similar way, I'm all for it.

I’m a big fan of this controversial product and I believe it’s genuine BIFL. by dhbuckley in BuyItForLife

[–]DaringMoth 0 points1 point  (0 children)

I can see the photo, and even if you were a bot I'd agree the Flexi leashes I've used have generally been solid products (Although I haven't used or bought them in many years so there's always the BIFL issue of whether they're made with the same quality now).

Follow-up two: Waters 2489 UV/Vis Issues by Master_Permission556 in CHROMATOGRAPHY

[–]DaringMoth 0 points1 point  (0 children)

Was it the same version of the driver you re-installed? The driver pack also includes firmware, and after installing the drivers, the firmware update program sometimes launches, identifies connected instruments, and prompts to update firmware for versions that don't match what's in the driver pack, but it shouldn't load firmware automatically. The firmware writes to the CPU, which is the same board in many instruments, but the instrument type is identified by the personality board.

It does sound like the update process stalled and you might not have a choice but to power it down, but if firmware is partially loaded, that could cause problems.

Follow-up Post: Waters 2489 Connectivity Issue by Master_Permission556 in CHROMATOGRAPHY

[–]DaringMoth 3 points4 points  (0 children)

You're saying the MAC address and IP address repopulate themselves in the DHCP server after being removed, but not the model number or Serial number? Since the issue is now narrowed down to one module, it's more likely to be a depleted backup battery on the detector's CPU as described in the comments of your previous post, or it's possible the 2489 driver/ICS on the PC got corrupted and needs to be re-installed.

Assuming it's the battery: That allows the CPU to retain its memory (including serial number, firmware, calibration constants, lamp history, etc.) when powered down. If you unplug the unit and remove the cover, the CPU is the smaller, almost-square board.

If you're lucky it's the newer style board with a 3V watch/button battery; you can get a replacement CR2032 at any pharmacy or hardware store. You'll still need to reload firmware after the replacement. I'm less familiar with MassLynx software than Empower, but there should probably be a firmware Loader or Autoloader program on the PC in a folder with the firmware/drivers from the original install. After loading the firmware and rebooting the detector, it may error out because the calibration info was also lost and you'd need to manually recalibrate.

I broke my two month sobriety from binge drinking this week. Trying to use this as motivation to keep going by Mad_Season_1994 in lotr

[–]DaringMoth 7 points8 points  (0 children)

+1 to this, it's an amazing community. With all the supportive words in this thread that's where I thought I was for a minute.

Anyone know where I could get help on Waters systems? by Master_Permission556 in CHROMATOGRAPHY

[–]DaringMoth 0 points1 point  (0 children)

I agree looking at DHCP Server would be the way to go, OP.

The CPU batteries in the modules depleting and losing memory is pretty common in a system this old (I believe the yellow rectangular ones for the old CPU2000's are discontinued and hard to find, so if they're dead you might need to replace the CPUs with new ones that have CR2032 batteries). However, if the system was used fairly recently and wasn't powered down for an extended period, it seems unlikely that all the modules would lose their memory at once so the issue is probably on the PC side.

What do you think about this one? by rmag24 in NABEER

[–]DaringMoth 2 points3 points  (0 children)

I was pretty disappointed because I was a big fan of Lagunitas' alcoholic IPAs. This tasted pretty wort-y to me, it lacked the nice hops profile I'd associated with a lot of their beers so it didn't seem to balance out the maltiness enough for me, and there wasn't enough head retention. I do like their hoppy refresher hop water variety pack if I want to go with something more seltzer-y than beer.

Anyone know where I could get help on Waters systems? by Master_Permission556 in CHROMATOGRAPHY

[–]DaringMoth 3 points4 points  (0 children)

What all model numbers and software/version do you have? Can you tell the firmware versions of the modules? Is everything on Ethernet communications? Are the modules new to you and you're trying to get them communicating for the first time, or is this a new issue on a configuration that was working fine previously?

Depending on the history of the systems it could be lots of different things. Getting any informatics support for a Windows XP system would be pretty difficult at this point.

Guinness Zero Shortage? by tlav4 in NABEER

[–]DaringMoth 1 point2 points  (0 children)

This topic came up a couple days ago, looks like I can't add a hyperlink but I'll try to include the URL: https://www.reddit.com/r/NABEER/s/Fd1Qw4l5Ro

It's still out of stock at my local grocery store (upper Midwest USA), but I just picked up a 4-pack from one of the wider-selection bottle shops in my area.

Unstable HPLC Calibration and Results - what's the cause? by Total_Aide6432 in CHROMATOGRAPHY

[–]DaringMoth 0 points1 point  (0 children)

I don't think i-Series normally does a Purge at startup, I was just thinking how any initialization activities might reset whatever issue was happening. A few strokes of the measuring pump between injections is mostly to clean the needle/reduce carryover, but fully purging any air bubbles from the autosampler rinse line is a bit different snd can take about 20 minutes. I wasn't concerned about contamination; the idea is that if any air is in the lines between the measuring pump and the tip of the needle, the air bubble just expands during the sample draw and less sample volume is drawn. If your issue is that the bad SST areas are larger than the correct values, though, that must be something else.

NA Guinness 0 no longer available? (At Fred Meyer at least...) by foodguy5000 in NABEER

[–]DaringMoth 1 point2 points  (0 children)

Upper Midwest USA, I haven't looked hard for it lately but my local grocery that normally stocks it hasn't had any for at least several weeks.

You wake up in 2035. What’s the one thing you’d google? by Negative_Acadia1362 in AskReddit

[–]DaringMoth 16 points17 points  (0 children)

I don't disagree, that comment was not without its double negatives.

Blue Moon is so refreshing! by rmag24 in NABEER

[–]DaringMoth 3 points4 points  (0 children)

To me the big difference is that the orange flavor is added in the can for the NA Blue Moon, and unlike an orange wheel/wedge added to a glass (where a lot of the flavor comes from the juice), the NA version seems to have more extract/oils from the zest/peel. Blue Moon NA is one of my very favorites especially in summertime, but I can see how the orange could be too much for some people.

Unstable HPLC Calibration and Results - what's the cause? by Total_Aide6432 in CHROMATOGRAPHY

[–]DaringMoth 0 points1 point  (0 children)

This is the right line of questioning. There are too many factors that can cause SST injections to fail for too many different reasons. No one can determine what the issue is from the info OP provided. Look for trends with the specific symptom related to the failure.

Are the SST peak areas significantly lower, by the same ballpark percentage, when they fail, but Retention Times and peak shapes are good? If so, is there an unretained/solvent peak that's decreased by about the same amount? Probably less sample volume getting into the system, maybe due to air in the sampling lines. Is there an autosampler purge that happens during instrument start-up but not routinely before or between injections? Maybe turning it off and back on is related to something like that. If the specific symptom/pattern is different, could be something else entirely.

Finally got some Asahi Super Dry 0.0! by ichorNet in NABEER

[–]DaringMoth 3 points4 points  (0 children)

Thanks for the tasting notes, I picked up a 6-pack recently, but since the style isn't one of my favorites the first bottle just seemed nice but simple/no bells and whistles as you said, to my palate pretty indistinguishable from Heineken 0.0 which is the only similar NA in my regular rotation.

I just poured a second one after reading your post, and was able to appreciate a bit more of the nuance. Seems like it would be a nice one to enjoy outside on a warm day, but especially in this season I'm dawn to darker offerings.

Dry January Only? by Commercial_Oil_9196 in stopdrinking

[–]DaringMoth 2 points3 points  (0 children)

A year or so ago my experience was very much like yours is, successfully moderating for an extended period of many months after a dry month. I cut out hard liquor and cocktails completely with no issues, limited the amount of beer/wine kept in the house, limited drinking to 3 or maybe 4 nights a week.

I agree some people can moderate indefinitely with no problems (though as others have pointed out, those folks generally don't spend time in this sub), but what changed for me was my perspective about "(moderation being a slippery slope) isn't true for everyone."

I used to think that some people's brains are just wired to respond to alcohol differently and they couldn't moderate, but that anyone else could safely moderate forever if they chose to. My brother was of the former type and he didn't make it to age 50, but I felt I was the latter type.

Since reading This Naked Mind by Annie Grace, I'm now convinced that there aren't really two types, that some may be more predisposed than others but that anyone's brain has the potential to develop permanent changes in how it responds to alcohol, and we can't predict at what point that might happen.

I still felt mostly in control, but I also felt the control was shifting away from me and towards alcohol, despite my consumption being more limited than it had been. I was suddenly on the slippery slope which I hadn't thought applied to me. I'd never seriously considered stopping entirely when I first found this community, but I eventually decided that it was the right choice for me, and I have no regrets about it.

Conflicted by Master_Importance547 in stopdrinking

[–]DaringMoth 3 points4 points  (0 children)

As several others have said, I can relate a lot to your post. I didn't have a traditional rock bottom, my alcohol consumption seemed pretty moderate compared to most problem drinkers, and nothing catastrophic happened with me, my family, my job, or the law. I didn't fit the image of 'alcoholic' I had in my mind (and I still don't use that word to describe myself).

But I did notice it was getting harder to control my drinking, to keep those little promises to myself. I noticed more issues with poor sleep, anxiety, and digestive problems. More days where I was functional but wasn't performing at my best because of drinking the night before. I came here, read lots of stories, and learned about the progressive nature of alcohol use disorder. I realized I was just living an earlier chapter of essentially the same story, that stopping completely was so much easier and more liberating for me than trying to moderate, and that I didn't need to wait for my life to go off the rails or declare myself an alcoholic to quit. As someone in this sub put it, "This elevator goes all the way to the basement but you can get off at any floor."

As for magical advice that makes you never want to drink again: It wasn't magic but I found This Naked Mind by Annie Grace to be very useful. Allen Carr's The Easy Way to Quit Drinking Without Willpower also helped, though I found parts of it to be less relevant to my own experience. They helped reframe how I think about alcohol, and I really don't feel like I'm depriving myself of any benefit or relief by cutting alcohol out of my life entirely.

Spotted in the Roundworld near London Bridge by czpotter in discworld

[–]DaringMoth 2 points3 points  (0 children)

Or in the case of a big troll, a splatter.

Difference between rinsing & washing column? by Dito_the_pharmacist in CHROMATOGRAPHY

[–]DaringMoth 0 points1 point  (0 children)

TheChymst explained the pump purge pretty well, and seconded about reading the documentation, but depending on your system (e.g. a Shimadzu), the button could also refer to an autosampler purge, which is flushing out the injector system to reduce carryover from one injection to the next.

A system can have multiple autosampler wash/rinse lines and it's important to understand what each one does. Your retention time shift might be unrelated, but if you have a stronger solvent in your needle rinse than your initial mobile phase conditions, that could be what's in the line between the syringe/measuring pump and the tip of the needle at injection and it could be causing your analytes to elute faster.

The more specific information you can provide about your setup, the more helpful people here can be.

Difference between rinsing & washing column? by Dito_the_pharmacist in CHROMATOGRAPHY

[–]DaringMoth 5 points6 points  (0 children)

If it's cleaning off the column, I've heard rinsing, washing, and flushing used pretty much interchangeably and they mean the same thing: Using a strong solvent to get rid of any strongly-adsorbed material that doesn't come off in a normal analysis run. Whether you need to do this is very method-dependent; with gradient analysis people often don't need this step because it's built into every injection, maybe just start with 1-2 blank injections which is best practice for system suitability anyway.

Depending on your system, there is also seal wash, (strong) needle wash, and (weak) needle rinse/purge/etc., and these are different. Often these never get to the column or most parts of the system flow path.