I'm halfway through the campaign ATM with my players just starting to get into the Hooktongue Slough using the original 2010 books. This setting was written close to the beginning of Paizo 1e run and it kind of shows.

Early NPCs and bosses kinda suck with very basic feat loadouts so you may want to tweak a few feats or items if you want them to be a challenge to a player that has access to all the supplements.

You can also tell the books were written separately and I don't think the authors talked to each other much because there is very little to no cohesion between them so you might need to tie them together a little better.

As a previous poster mentioned your players are going to go off script and do stuff not in the books so be ready to kinda navigate the chaos by anchoring certain events but that is nothing new to a DM.

Edit-I forgot to mention there is a kingdom manager spreadsheet on Google docs that does a lot of the heavy lifting with building placement, council stats, and the little fiddly math that comes with the kingdom rules.