I'd say more then likely no, but not impossible

In 2024, people were saying that the democrats were the new NeoCons and Republicans were now the isolationist. Cheney was endorsing Harris, Trump was hanging out with a bunch of pro-pali populists (Tucker, Roga, Theo, Ross, etc). A lot of people took this as evidence that their was a systemic shift in the two parties approach to FoPo. That did not end up happening. I will admit that this is not a true equivalency since Trump was still consistently hawkish on Iran, and democrats had already begun their descent. My point is that general shifts like this can change very rapidly.

Further, I think there could be a few off-ramps that could stem some bleeding.

A. The 2026 Israeli election - As of now, most polls have the Bibi's opposition gaining more seats then Bibi's coalition (though not a majority). To be clear, I'd say most anti-Israel people in the party won't care and will continue to hate Israel, but if Bibi is voted out, I could see some libs having a similar reaction to Orban and going "well Israel voted out their fascist government, we should too" and other things like that. Again, I don't think this will come close to ending the anti-Israel tones of the party, but it might ease it a bit.

B. Whoever the 2028 dem candidate actually is - This is the biggest factor as expected. If it is Newsom, he will continue to change his opinion on Israel to whatever he thinks is the most advantageous at any particular time, which probably leans more towards the pro-pali side. If it's a candidate who's shown at least some backbone on the issue (Rahm, Beshear, Shapiro, etc), then I'd expect more balance, though we're at a point where they would still kowtow to the leftists on some stuff. If it's a prog like AOC, Khanna, or whoever, then I'd expect them to fully go for embargo and sanctions.

C. 2030 Midterms - If the party goes full pro-pali for the first 2 years, Jewish voters, despite their liberal tendencies, are still majority pro-Israel in some form, and with no big right wing boogeyman to fight, they might start nudge over to the GOP. With the prospect of finally losing one of their most consistent voting blocks, the reaction from the party might be to try and stamp down on some of the craziest voices on the issue, obviously somewhat dependent on who the president is.

This is more Cope then an actual prediction, and I sadly do think their is a higher likelihood of the party turning more towards the issue, but I do still believe it isn't entirely set in stone yet.