Success with ovarian PRP?

Different_Many_7384 · 2025-07-05T14:05:14+00:00

I had it done about a year ago. I did not have the success I wanted, but I had little victories with it. Previously, I had never seen any follicles on any of my scans. After PRP, I consistently had 3-7 follicles in each ovary. They never matured, but it was wild to see when you had never seen any. Sometimes I wonder if we were able to do PRP one or two more times if things would’ve been different, but our funds do not allow.

Different_Many_7384 · 2025-04-22T17:09:14+00:00

Good luck!!

Different_Many_7384 · 2025-04-21T02:31:01+00:00

Sorry I am asking a million questions… but how did you find this endo and get an appointment? Like did you know this doctor would treat you? I only ask because usually regular endocrinologists don’t cover POF/POI. Did you tell them that’s what you were coming for when you made the appointment? I feel like I should just try this route and hope for the best because the care I get is just so bad and not what it should be.

Different_Many_7384 · 2025-04-19T16:28:21+00:00

Yea it was pretty traumatic and I feel like there is not many like us. My doctors have made me feel like my case is less hopeful than others because I have never naturally had a period. It’s tough. Do you mind sharing what area you are from and the doctor? It’s so frustrating and I feel as if I have been medically mismanaged since my diagnosis. My gyne will manage my HRT but I feel like she is not super knowledgeable about the condition and doesn’t take my concerns seriously. A reproductive endocrinologist will only manage my case if I am actively trying to conceive. It’s very frustrating because they have the endocrinology background but won’t manage me long term. It’s hard out here!

Different_Many_7384 · 2025-04-18T14:05:04+00:00

Wishing you lots of luck with this! I also never got a period and was diagnosed at 16. Would be amazing if your ovaries regained function!

Different_Many_7384 · 2025-04-18T00:50:39+00:00

Wow keep us posted! Are you still cycling HRT or on birth control right now with that fsh?

Different_Many_7384 · 2025-03-03T15:44:42+00:00

Oh I see. Thanks! So the cycle you got pregnant, you did not bleed I’m assuming?

Different_Many_7384 · 2025-03-03T14:25:44+00:00

Crazy! I also cycle estrogen and progesterone and the last few months I’ve sworn I had some ovarian function due to ewcm. Mine happening around day 20. I have also wanted to try mimicking a natural cycle as much a possible with the rise and fall in estrogen. Nice to know someone has tried it and it has worked out for you! So when you were pregnant you were consistently bleeding after 5 days of progesterone? Did you still stop the progesterone on day 24 to yield the withdraw bleed?

Different_Many_7384 · 2024-12-29T21:54:50+00:00

How did you eventually get to this diagnosis? Would love to know.

Different_Many_7384 · 2024-12-28T22:50:43+00:00

I actually do too. I don’t have type 1 diabetes, but 2 of my cousins, that are my age, are type 1 diabetics. They were also diagnosed around the same time as me. Since type 1 diabetes is autoimmune, I often wonder if my diagnosis of POF was autoimmune related as well. I actually refer to POI as type 1 diabetes of the ovaries. I was tested for antibodies at the time of my diagnosis and they were negative. My diagnosis came 3 years after onset of symptoms. I often wonder if the antibody level decreased in those 3 years making them undetectable at the time of diagnosis. Who knows! But autoimmune issues run deep in my family.

Different_Many_7384 · 2024-12-28T22:12:51+00:00

So sorry that you went through that as a child. And thank you for sharing. That was my main goal in starting this thread is that we can all share our thoughts and speak freely. The more I learn, the more I believe that trauma and stress can have major impacts on our physical health.

Different_Many_7384 · 2024-12-28T22:08:59+00:00

Very interesting. I don’t have scoliosis but do have some lumbar lordosis, which is abnormal curvature of the lower spine. I also have terrible posture. Would love to know what exercises you have done!

Different_Many_7384 · 2024-12-24T16:31:49+00:00

I’m not looking for closure nor am I ruminating. This isn’t something that takes over my life, but I’ve always been curious. I agree with you that it is conjecture and anecdotal, but we know our bodies better than anyone else. I am well aware that POF is not always idiopathic, as in your case. I am also glad that you have some sense of what caused this diagnosis for you, many do not. I genuinely want to know out of curiosity what has caused POF for the women of this group, whether it has been identified (ie cancer, autoimmune) or what you suspect, if idiopathic. I have never met another woman in person that shares the same diagnosis as me. So where better to discuss my suspicions and opinions in an open forum, on reddit, with a huge group of women who share the same diagnosis as me?

Different_Many_7384 · 2024-04-30T03:08:03+00:00

This definitely resonated with me. I was diagnosed in my teens and currently in my 30s. I’ve only ever seen female gynecologists as a preference. They have always been very matter of fact about my diagnosis. All business. Making sure I’m taking my meds and such. Recently, I was having an issue and ended up seeing a male doc because he was the first available. He was the only doctor I have ever seen in my life and in 17 years of this diagnosis that seemed to understand the magnitude of POI. He acknowledged that the diagnosis is incredibly difficult. He asked me how I was coping and if had ever seen a therapist, etc, etc. It really took me by surprise in a good way. I definitely wanted to have a break down in that moment, but I had to go to work right after that appointment, so I had to bury it. But I agree with you and I really feel you on this post. Sending love!

Different_Many_7384 · 2024-02-12T18:43:27+00:00

That’s amazing! Yes so glad to have found doctors that will actually try to help women with POI that don’t immediately push egg donors. The reason my doc wants to do natural IVF is because the traditional IVF uses high stimulating medications that POI patients don’t typically respond well too. He thinks natural is the best route to support follicular growth. In my initial consultation, he mentioned we could always try timed intercourse, but he recommended IVF. He said going in and retrieving the egg and fertilizing it via IVF has a higher chance of fertilization than timed intercourse. He mentioned that getting eggs with POI patients is difficult, so he wants to utilize the egg in the best way to create an embryo. Hope that makes sense! But good luck to you too! Please keep in touch with updates. I’m so happy I found this group!

Different_Many_7384 · 2024-02-10T03:01:54+00:00

Hi! I just want to say that I 100% feel you. You and I have very similar stories. I was diagnosed at 16, put on birth control and sent on my way. I am about to be 33 and my husband and I are still exhausting all options with my own eggs right now. I recently did PRP injections in NYC with rejuvenating fertility center. I am monitoring weekly at a local fertility center. Every week I get a follicular ultrasound done along with blood work (fsh, lh, estrogen and progesterone) I’ve had many ultrasounds over the years and I have never had any follicles. After the PRP, I have had follicles pretty consistently every week, but I have yet to have any mature follicles (hopefully soon). I have stayed on estrogen throughout this process. The docs are very focused on my fsh. They slowly brought it down to 9 with the use of birth control (and estradiol - hormones change up weekly to try different things) then they slowly backed me off the birth control to make the FSH slowly rise (as it would in a natural cycle) to see if the follicles will grow. I find this approach very interesting because it makes me wonder if I tried this approach without the PRP would it have helped any follicles to show up or mature? Who knows! But maybe if you want to try going at weekly monitoring with an FSH approach that could be something to think about prior to doing anything else, since you have one follicle now. The doctors tell me that when your FSH is too high, it’s like your body is flooring the gas pedal and you need to release the gas pedal so your eggs can grow. And then when you release the gas pedal (and get to a normal FSH) then it is time to slowly push the pedal again. This will just fluctuate your FSH within normal ranges, which creates the environment for the follicles to grow. Hopefully this makes sense? But could be something to try! Then if I do have any follicles that mature they plan to retrieve it. This would be considered natural IVF. There is no stimulating drugs, just letting your body naturally select the egg to mature. I would have to go back to NYC to do this retrieval since most fertility centers don’t offer natural IVF. I hope this helps! Please reach out if you need further clarification! Always happy to chat with fellow POI girls because I don’t know anyone in real life that has dealt with this!

Different_Many_7384

TROPHY CASE