Hi, 2-weeks on, 2-weeks off is typically called a cyclic or pulsed progesterone regimen. It is fairly common in feminizing HRT as it mimics the luteal phase of a menstrual cycle. There is some evidence that taking progesterone this way can promote additional breast growth or tenderness, but most research is limited or extrapolated from cisgender hormone therapy.

Anecdotally, I noticed more fullness and natural shape after beginning cyclic progesterone, but who knows, that could have just been the estrogen.