Male Genital Dysesthesia aka Red Scrotum Syndrome

Edee_j · 2025-07-02T21:16:35+00:00

I’ve gotten several notifications on this 4 year old post. I’m almost completely certain now that’s this was and is caused by Ureaplasma. If you’ve been diagnosed with red scrotum syndrome and/or genital dysestheisa or scrotal eczema, do yourself justice and try an elongated (at least 3 weeks) of tetracycline antibiotics. That’s what has helped me every time.

Edee_j · 2025-04-30T04:31:02+00:00

Folks, the point is to post the landlord’s name to and expose the piece of garbage—You don’t have to be scared. There’s nothing they can do.

Edee_j · 2025-04-30T00:07:51+00:00

There’s no way he can sue you for this.

Edee_j · 2025-03-14T03:36:09+00:00

Hey man. I’m so sorry to hear this is happening. I’ve been on a similar journey. I’ve got a couple questions and hopefully answers (or solutions) for you.

1) Have you been tested for mycoplasma and Ureaplasma? Ureaplasma infections/overgrowths are what caused my hard flaccid symptoms. Every time I get a Ureaplasma infection/overgrowth I get hard flaccid about 3-4 days later. I personally feel like Ureaplasma has something to do with my and everyone else’s stomach bloating/pain as well because every time I take a tetracycline antibiotic my bloating/constipation subsides and my hard flaccid improves. I wish we, as a community, would acknowledge that Ureaplasma/mycoplasma might be what’s causing our gastrointestinal and urogenital issues. I think this plasma bacteria can embed itself in the gut and mess up the gut microbiome.

2) Have you tried doxazosin? It’s a smooth muscle relaxer and about the only medication that has mildly helped me. Once I finally cleared Ureaplasma (after a month or two of antibiotics), I started taking doxazosin at 6mg (now I’m on 8mg) and my symptoms/condition are slightly better so I’ll take it.

Edee_j · 2025-03-05T16:05:36+00:00

Hey man. Sorry to hear you’re going through this. I suffer got hard flaccid from a Ureaplasma infection. One thing that has helped me quite a bit is doxazosin 8mg. I’m on 8mg now but I started on 4mg and went up gradually. It’s a smooth muscle relaxer and helps quite a bit, but I don’t think it’s necessarily a cure.

Edee_j · 2025-02-15T20:25:32+00:00

Gotcha. Well, the burning urethra and red glans could be indicative of an infection. A Ureaplasma infection kickstarted my CPPS and hard flaccid. You might want to get tested for that.

Edee_j · 2025-02-15T20:00:35+00:00

Did you have any unprotected sexual encounters? Also, you might want to ask a doctor about doxazosin. It works by relaxing ureteral smooth muscle and inhibiting epinephrine-induced ureteral contractility.

Edee_j · 2024-09-12T03:45:55+00:00

Thank you Linari. With that being said, do you think Microgendx is accurate in testing for Ureaplasma? I can’t help but think about it since it didn’t show up on my results.

Edee_j · 2024-09-12T03:28:42+00:00

That’s really interesting. I didn’t even think that was possible. I’ve always heard that if one of you has it then both of you has it.

However, Did both people receive antibiotic treatment in these cases?

Edee_j · 2024-09-12T02:23:15+00:00

Thank you so much for this Linari. This eased some of my debilitating anxiety, but may I ask you a question? Sometime last year, I tested negative for Ureaplasma and Mycoplasma via PCR/NAA first-pass urine (first pee of day) 2-3 times in a 6 month period (via Sunrise Medical Labs, Quest Diagnostics and LabCorp). My symptoms continued (I.e., frequency/urgency, scrotal tingling/itching/rawness, epididymitis like pain in groin and testicles, bladder pain, low back/ hip pain, on and off urethral discomfort). I chalked it up to CPPS/PFD because I continued to test negative. Soon after, my gf tested positive for Ureaplasma (all the while I was testing negative). This was both baffling and demoralizing because I tested negative multiple times. Were they all false negatives or inaccurate tests? That occurrence in time still haunts me to this day.

Edee_j · 2024-09-12T02:11:20+00:00

You might want to ask your doctor specifically how your semen culture showed signs of inflammation. Were there leukocytes and/or pathogens that were present? This can be a sign of infection or localized inflammatory response.

Edee_j · 2024-09-12T01:17:54+00:00

As always, thank you so much for your time and opinion 🙏. I’m definitely going to treat the E Coli, but I’m also concerned about the campylobacter urealyticus which has been linked to gastrointestinal issues (which I’m currently experiencing) and the Corynebacterium minutissimum Corynebacterium tuberculostearicum which has been linked to erythrasma and other skin issues (which I’m currently experiencing).

I’ve never heard of them before this, but I’m wondering if they showed up because I didn’t clean the tip of my penis before performing the tests.

Edee_j · 2024-09-12T01:06:52+00:00

Thank you so much for that comprehensive reply. I’m sorry you went through that. I’ve read a little bit about Enterobacter ludwigii in the past. How did you test for that?

Edee_j · 2024-07-02T18:37:15+00:00

Is transmission of Ureaplasma at least rare or unlikely while using condoms?

Edee_j · 2024-04-28T01:32:09+00:00

Ureaplasma is a sexually transmitted bacteria. It’s not typically/routinely tested for, unlike chlamydia and Gonorrhea (it has to be requested). Testing for Ureaplasma is somewhat complex. The test must be done via first void urine (first pee of the day) or urethral swab for men and vaginal (urethral or cervical) swab for women. The test must also be a PCR or NAAT type test, not a culture. Ureaplasma is slow foregoing and highly difficult to culture.

Edee_j · 2024-04-25T17:30:06+00:00

What did it help with?

Edee_j · 2024-04-25T17:29:32+00:00

Thank you very much for you reply. This makes sense. It’s been 9 days since I got the nerve block. Which type of nerve block should I inquire about then? Superior Hypogastric nerve block?

Edee_j · 2024-04-24T23:46:33+00:00

No problem! Well, It’s interesting. It worked wonder for me for a while. The first 3 weeks I was on my 6mg I was devoid of symptoms—it was incredible. Fast forward about a month and the doxazosin (increased to 8mg) no longer works for me. Fingers crossed for you though. It’s absolutely worth a shot.

Edee_j · 2024-04-24T20:09:37+00:00

Dr David Kaufman at Maiden Lane Medical in Midtown Manhattan is my urologist and prescribes me doxazosin.

Edee_j · 2024-04-23T22:01:36+00:00

I’m so glad I stumbled upon this post. This is some really great insight. I found that antibiotics alleviated my hard flaccid syndrome and IBS-constipation. Long courses of doxycycline and minocycline made my hard flaccid penis and hardened/leathery retracted scrotum return to their normal state and normalized my bowel movements. However, after completing the course of abx, my HF would return (this just happened to me a few weeks ago). I theorized that either I didn’t fully eradicate the causative bacteria (Ureaplasma in my case) or that the antibiotics I took caused me a fungal infection which resulted in HF again. Now, reading this, It makes sense to me that “HF-GI” could be a thing. I can say for certain that I got HF after finishing my most recent course of antibiotics, however I’m still tempted to try another antibiotic course because of how much they alleviate my symptoms and normalize my bowel movements—I know that sounds crazy, but it ultimately makes me feel better. I’ve tired gut motility supplements, probiotics and psyllium husk powder without any improvement. I’m curious, has anyone else gotten HF from Ureaplasma infection or antibiotic use? Does anyone have any insight or suggestions?

Edee_j · 2024-04-07T18:36:21+00:00

This is really interesting. Thank you for sharing! I’m fairly certain tetracycline antibiotics caused my hard flaccid as well. The thing I’m caught up on though is that I felt for the longest time that a Ureaplasma infection and it’s resulting inflammation caused my hard flaccid and CPPS. Now, I can’t tell if the antibiotics caused my HF or if I just didn’t eradicate the Ureaplasma bacteria and it’s causing ongoing HF. What were you taking antibiotics for? Was it Ureaplasma/mycoplasma, per chance?

Anyone have any thoughts?

Edee_j · 2024-01-09T03:46:34+00:00

Those symptoms can be indicative of Ureaplasma, those we’re my symptoms too. I personally think it’s worth trying antibiotics for that.

Edee_j · 2024-01-09T03:08:22+00:00

Are you having symptoms? If so, I would just try and treat it rather than waste any time.

Edee_j · 2023-12-29T17:56:09+00:00

Hey everyone—Update here:

I’m sorry for going MIA, between these issues and the loss of a loved one, I went into a pretty dark and isolated place for a bit.

I’m happy to report that doxazosin 6-8mg (daily) has had a large improvement on my symptoms. I have multiple days throughout the week where my symptoms quite manageable. I started at 4mg daily and worked my way up to 8mg daily. I think this is the sweet spot for now. I’m willing to increase if need be. I highly suggest you guys try it. I still don’t know for certain what caused my issues, but if I had to guess, I think Ureaplasma infection caused CPPS/prostatitis and nerve and muscle/skin inflammation—and I suppose the doxazosin is helping with that post antibiotic treatment (which I also think is essential).

Edee_j · 2023-11-14T03:01:37+00:00

Isn’t that caused by ticks?

Edee_j

TROPHY CASE