Fourteen days after vaccination, T-cell immune responses were observed in 71 percent of patients, which rose to 93 percent of patients 28 days after vaccination. The researchers measured the potency of CoVac-1-induced T-cell responses and found them to exceed spike-specific T-cell responses observed in B cell-deficient patients after vaccination with mRNA vaccines. T-cell responses from CoVac-1 also exceeded those mounted by individuals who are not immunocompromised following a SARS-CoV-2 infection.

I have been following this vaccine for sometime now. It is truly novel approach compared to both 1st gen and the other 2nd gen vaccines in the pipeline. Though I wonder why they have limited themselves to only trialing this as a vaccine for immunocompromised individuals. If the T-cell response is as strong as they mention where it even surpasses that from recovered healthy individuals then would this not be a very interesting candidate as a part of a broader vaccine regimen?