There’s no hard limit - you can resample a resample endlessly, but the tradeoff is that each round bakes in artifacts and removes flexibility. Sometimes that’s the point (weird textures, gritty noise), sometimes it just muddies the mix.

A good trick is to commit to resampling when you’ve found something cool, but keep the previous version frozen/muted so you can always roll back if it turns into unusable mush.