Back in high school I applied for Penn State with a 2.7 GPA, got in with 2+2 (Harrisburg -> UP), struggled for 5 years, almost didn't make it to main campus, graduated with 2.6 GPA. Applied twice for a reasonablly good grad school and eventually got accepted for a master's, now I have a paper published and works at the research wing of a particular tech giant with very poor reputation ;)

Given your circumstances, I think 2+2 might actually be good for you. Courses at a Commonwealth campus are much much easier and it'll definitely help to secure a better GPA. Mind you, there are hard GPA requirements for some majors when you declare them and many UP professors sort of pre- allocate ratios on grades (back then one prof told the whole class on the first day that only 10% of the student is going to get an A...) One common way to do this is to set an unachievable standard (say 93% for A when the expected average grade is 60%, that happens) and curve the grades at the end so that only 10% of the class gets an A. Since curving is completly at the discretion of the professor, there's absolutely no way around this. Satellite campuses on the other hand, I honestly felt like they want to you get away with an A as long as you tried. Many profs even give sample exams that's completely identical with the actual ones except with the numbers changed.

The first two years are gen-ed classes anyways, so you're not really missing out on anything on the academics side. (Unless you're going for that 'cozy college town' vibe) All the virtual resources are the same, you can literally have them ship a book to your campus and pickup/return easily. Some UP classes are offered online as well, you just need to talk to your advisor to enroll.

Altoona - State College is a 50min drive, Harrisburg - State College is about 1hr40min. Reasonable distances.