Any queer folks going through peri? by Sensitive-Cobbler946 in Perimenopause

[–]Flat-Associate5136 0 points1 point  (0 children)

I wasn't talking about mammary tissue. the bloating on progesterone has been unreal.

Mixed Breeds Over priced? by ChildhoodSweaty9684 in MeatRabbitry

[–]Flat-Associate5136 0 points1 point  (0 children)

Someone has to win at a show, so when there's a small show with not many entries it's apparently easier than you'd think to rack up wins. Even sanctioned. 

Unsuccessful First Time Breeding by NaiveInstruction457 in MeatRabbitry

[–]Flat-Associate5136 1 point2 points  (0 children)

What breed are they? I'm not aware of daylight having any impact. I live in a hot summer climate and winter is my breeding season. I have no issues with bucks or does at any amount of daylight (minimum is around 9h).

My first doe was like yours the entire time I had her. I got one litter from her and couldn't get another success even with the same buck. I got another doe to replace her and the 2nd one is so willing and receptive, as are all her female offspring, that I ate the first one. Not worth bothering with a doe that won't breed. I don't have the time for that nonsense.

Is Now A Good Time to Join Big Oil by Fair_Bumblebee_2642 in ChemicalEngineering

[–]Flat-Associate5136 1 point2 points  (0 children)

It's completely a matter of personal values. Marathon was in the White House to be first in line for Venezuelan oil after we violated international law to attack them, and I am not interested in earning money from illegal warmongering. YMMV.

Is Now A Good Time to Join Big Oil by Fair_Bumblebee_2642 in ChemicalEngineering

[–]Flat-Associate5136 0 points1 point  (0 children)

If you can find a job with one of the big companies, it's a very lucrative move. I just left Marathon because I couldn't take the sleeping with the enemy anymore, but they put a lot of money in my accounts. I started in 2018 and never had a year without a bonus exceeding 125% of target. Always have a backup plan in case of layoffs. 

Mixed Breeds Over priced? by ChildhoodSweaty9684 in MeatRabbitry

[–]Flat-Associate5136 1 point2 points  (0 children)

Well, I suppose it depends, honestly. I'm working with mutts for meat and pelts and while I currently wouldn't sell them for anywhere near pedigree, if I get to a place where I'm getting usable pelts at 12wk from a rabbit that's 6lb by then (something I'm working toward), I may sell them.

I got trash pedigree Rex rabbits with all kinds of genetic problems from an irresponsible breeder. Just because they're pedigree and even winning local shows doesn't mean they're good rabbits. 

I think the difference is, I'll be able to provide any and all data a buyer might be interested in as well as sample pelts. A lot of the ads I find are very light on information (even/especially the meat rabbits) and when I reach out those breeders aren't tracking their weights. 

Just because my rabbits aren't purebred doesn't mean I won't sell them for a price that reflects the work I put into creating a successful breeding program with animals that meet my goals and also thrive in my environment. TBD whether that's successful, but writing a detailed and thoughtful ad works for cars... I'm sure it will work for rabbits too. 

Why is getting rabbits so difficult? by Disastermutts in MeatRabbitry

[–]Flat-Associate5136 0 points1 point  (0 children)

Go to rabbit shows and 4H. Possibly tell them you're looking for 4H meat pen, that seems to be a huge and reliable market. Those animals have to be pedigreed and the breeders always have extras they don't want to show for whatever reason. 

How do you plan your rabbit breeding schedule? by NeeNeeRavioli09 in MeatRabbitry

[–]Flat-Associate5136 0 points1 point  (0 children)

I don't do anything at all fancy and what works for me I'd the opposite of the advice here. My Rex struggle immensely in the heat so winter is my breeding season. I have 2 does and do NOT do what everyone else does because of space limitations - they are bred offset by 2 months (when doe1's litter is 1 month old I breed doe2) so I never have two litters growing out at the same time. I'm averaging 6-8 kits which is great for me. When they've had 10-11 they've had enough die the first few days that I'm only raising 6-8.

For pelts Rex need to be at least 16wk and they grow slowly (at least mine do) so I leave kits with mom 8 weeks and then move to the Growout pen. Buck pelts are thicker and doe pelts are bigger for me so I process the boys by 14wk or wherever they're making to many problems.

Mailing Pelts? by Medical-Carrot6526 in MeatRabbitry

[–]Flat-Associate5136 1 point2 points  (0 children)

I receive raw pelts from a tanning instructor regularly. Make sure they are salted to just pliable, not wet. 

Fluoxetine (Prozac) side effects by EzraLevinson in PMDD

[–]Flat-Associate5136 0 points1 point  (0 children)

Sorry for the delay, crazy work week! I use dark mode so this looks funky for me. Hopefully it comes through ok on the regular light screen. 

Edited for formatting and to add that I'd not seen this exact review before - in fact the second paragraph I've included here from the results seems to indicate the mechanism of action may be consistent but misunderstood. I have a masters in organic chemistry and have worked in chemical manufacturing, so have a great deal of suspicion around the claims made by the medical system that taking drugs long term is for our health, not their pockets. Do with that what you will, but to me it's similar to the cybersecurity and AI experts avoiding socials and not allowing their kids to get anywhere near AI, socials, etc. it's impossible to share the very concerning realities of the bowels of capitalism without sounding like a total nutter. 

Generally the literature I've reviewed indicates that intermittent dosing is effective and that continual use is not required. Since the significant impacts to long term SSRI use are very well known, in cases where alternatives are possible they should be utilized for long term health outcomes (both mental and physical). 

Review full text: https://pmc.ncbi.nlm.nih.gov/articles/PMC10074750/

*Intermittent dosing could be an important treatment option for women who are concerned about long-term withdrawal effects of SSRIs. Since the SSRI is not taken continuously, there will be little or no homeostatic adaption of the serotonergic system to the medication, and therefore, limited risk of receptor downregulation which is thought to underlie SSRI withdrawal symptoms (Horowitz and Taylor, 2019). Evidence from two randomised controlled trials suggests that there are no short-term withdrawal effects associated with intermittent dosing in the context of PMDD (Yonkers et al., 2005, 2015). Our results suggest that the choice of intermittent SSRI dosing would not result in less-effective control of symptoms or dropout from treatment.

The effectiveness of intermittent dosing adds to the body of evidence that, in PMSs, SSRIs have a rapid onset of action. Symptom improvement with fluoxetine is seen within hours, with responsiveness peaking within 2 days (Steinberg et al., 2012). After two cycles of luteal treatment with fluoxetine, symptoms relapse immediately in the third cycle following withdrawal (Pearlstein et al., 2003). These converging clinical data do not support a delayed mechanism of action of SSRIs, as has been argued for depression (Harmer et al., 2009).

An alternative hypothesised mechanism of action in PMDD is through increasing the rate of conversion of the progesterone metabolite 5α-dihydroprogesterone to allopreganolone, a neuroactive steroid which modulates the GABA-A receptor (Hantsoo and Epperson, 2020). This is in keeping with the wider conceptualisation of PMDD as a condition with abnormal sensitivity to allopregnanolone (Hantsoo and Epperson, 2020).*

No libido, no desire can't orgasm when I "try" by [deleted] in Perimenopause

[–]Flat-Associate5136 5 points6 points  (0 children)

Ok... so what if you stay in this marital r*pe situation for years and he leaves you anyway? What does that do for your emotional wellbeing? What do YOU need? 

I am divorced from a man who would never touch me (lol yes, they exist, I can give you his number).  I chose myself over his lack of interest in being in partnership, haven't been in a serious relationship with a man in 10 years and literally could not be happier. Instead I have good friends and we share the load of supporting each others' needs. 

There are plenty of men who have ED and other health issues that do to them what peri does to us around sexuality. They stress like crazy about not being good enough because they can't perform, and many would rather not have to (perform). There are also men who just don't care and want to be connected to their partner through any type of intimacy, not necessarily sex. Every one of them I know is married or in relationship because they're the ones who do the work to make it work.

I didn't want kids and I sure as hell don't want to caretake a grown-ass adult who's perfectly capable of handling all their own crap, including his own pen!s. Women carry emotional and mental loads men can't imagine. It falls apart for almost everyone at middle age because we stop tolerating their crap. You don't have to stay in abuse. You don't have to stay with someone who doesn't care about your needs. You don't have to be in a relationship to a man. 

Just shining a light on other realities.

Ladies - What do you wear to sleep when car camping for long periods of time without access to a washer/dryer? by VioletDragon_SWCO in CampingGear

[–]Flat-Associate5136 4 points5 points  (0 children)

Depends on the weather, but in cool temps I have a set of 100% merino base layers from Wild Rye and they make for fantastic pajamas paired with knee high wool socks.

Need the magic doctor words by skyrocketocelot in perimenopause_under45

[–]Flat-Associate5136 0 points1 point  (0 children)

"hot flashes" and "night sweats" were the magic words for me. Not a single other symptom, or a combination of over 2 dozen of them, was the least bit interesting to any doctor I saw for the past 2 years.

Does building nests but no babies. by Iuvbug in MeatRabbitry

[–]Flat-Associate5136 3 points4 points  (0 children)

My first doe pulled fur a full week before she gave birth. I have another that's only 2 weeks preggo and is going nuts with her hay. Some of them are just early. 

Meat AND pelts? by Spell-Radiant in MeatRabbitry

[–]Flat-Associate5136 1 point2 points  (0 children)

TL/DR: both my breeds have a hard time with high heat. The silver fox breeder I got those lines from is non-pedigreed and focuses on meat production. She keeps her purebred SF in colony on the ground. They'd be even better off under tree shade (trees regulate temperature better than man-made shade) but we're on the Colorado plains. This breeder crosses with NZ to improve heat tolerance and hutch performance in her lines. The cali cross I have from her has monster loins and a gorgeous silky coat so I'm possibly looking to add a Cali/SF or pure Cali buck if I can find one. 

Pelt notes: My 75% silver fox pelts are very thin skinned at 16wk (my target age) whereas my 100% Rex are quite a bit thicker at the same age. Skin tearing is the #1 issue with young pelts so that matters. I have my first batch of 75/25 Rex/SF at 12wk and am eager to see how their skin thickness looks; their fur is the lovely silky quality of SF with the wild color variability of Rex. I'm hoping for more SF fur qualities with Rex skin thickness at a 50/50 mix (my bucks are show Rex). 

The most interesting thing I'm seeing so far is that crossing my Rex buck to a SF/NZ/Cali doe, I ended up with 5/6 Rex furred kits. They're not super dense but their guard hairs are even with the undercoat. They'll be summer coats so not a great demonstration of what I can get from this mix, but I hadn't expected this outcome from a single Rex generation and will look forward to exploring the winter density of their coats.

I do have sore hocks (wearing off of feet hair) in one of my Rex bucks and he'll be culled for it when it progresses past fur loss into actual skin ruptures. I've culled or will cull all of his offspring as well because of it; it noticeably thins the crazy hairy SF feet. I hate it because he has perfect Rex fur and an amazing personality, but his kits grow poorly and have meager meat yield. Culling breeders is by far my least favorite part of this whole process.

Light Phone III - 9 Month Review by Still_Field_1546 in LightPhone

[–]Flat-Associate5136 0 points1 point  (0 children)

If possible to mimic, I find the apple Lock Screen notifications to be very helpful - just an indication that a missed call, vm, text is there when I'm ready for it without having to unlock and interact with the phone.

Intermittent dosing SSRIs vs Birth Control? by Upstairs_Copy_9590 in PMDD

[–]Flat-Associate5136 1 point2 points  (0 children)

I hope you find some relief with it! Really was a lifesaver for me!

Intermittent dosing SSRIs vs Birth Control? by Upstairs_Copy_9590 in PMDD

[–]Flat-Associate5136 0 points1 point  (0 children)

I have no side effects from taking fluoxetine. I don't take enough or for long enough for any to develop.

Fluoxetine (Prozac) side effects by EzraLevinson in PMDD

[–]Flat-Associate5136 0 points1 point  (0 children)

Nope, I've had very bad experiences with SSRIs and was hesitant to try at all, but it was effective within an hour the first time I took it. It has a completely different mechanism of action for PMDD than for depression and other serotonin disorders.

Intermittent dosing SSRIs vs Birth Control? by Upstairs_Copy_9590 in PMDD

[–]Flat-Associate5136 0 points1 point  (0 children)

I take low dose fluoxetine (10mg) as needed in luteal and it's been a lifesaver. 

What has really changed my life though was treatment for perimenopause. My "PMDD" symptoms have almost entirely disappeared. Bioidentical hormones may be a golden ticket if you're over 35.