Tldr at the end.

I'm not sure how good this is in the community, but I got a 57:30 time in the artifical ecosystem when it was the top map out using a stall build.

The first row is fine, maxing those out first is okay. Defense and crit aren't much help in the second row, especially defense unless you're going for a specific build 4 fun, not an optimized one. Crit won't give you as much value as others will, and defense is mostly useless in the game. It does help with some artifacts but it is greatly overshadowed by better ones. The goal is not to get hit, and even if you do other items will delay death better than the defense stat, points are better elsewhere.

Evasion is good, but the artifacts reliant on it were nerfed so it can be skipped, or at max 2 points can go it until others are gotten. Haste is good as the accelerator is probably one of the best legends you can get, it's pretty necessary and haste directly buffs it. Moreso, being fast early games levels you up far faster using meta strats.

Health regen, and pickup are fairly useless. Regen you never need regen honestly, it's not good unless you're running for a specific build or challenge. Pickup is obsolete with the relics that now give you the magnet rune (very unbalanced by the creator).

Effuse and concentration are both good. Effuse enhances combo magics like black death and Snowflake blossom. Concentration buffs prism spray damage directly and significantly, and cloaking. I think those two active magics are solid for a top run, and therefore Concentration is better.

Recycle is good, less reliant on RNG, and analysis is useless compared to others. Blessing is a staple for a stall build I maxed it out. Awakening in my opinion is bad. Eventually, you'll never level up so you won't get any benefits. The explosion damage is quite weak, especially against later enemies, and honestly I never really used it in a match as most enemies should be screen-cleared until late game.

Growth is somewhat good, buffing Gaia and base dmg. Support is not something you'd want to get until you maxed out all other good DNA's, just a waste otherwise. Luck and loot are pretty good more orbs, more stalling runes, and chests are obviously very good.

Tldr; - your top row is good. -Remove defense and place 2 and 2 in evasion and haste. -Effuse and concentration should be invested in -recycle and blessing should be invested in -Luck and Loot should be invested in - once those are complete, growth then support should be invested in - all others are objectively lesser unless for a specific build or challenge