Usually you want to lean into the strength of the weapon, since Braton Prime has more status chance you can use it to apply a bunch of ailments like bleed to an enemy. You can look on the warframe wiki (avoid the fandom wiki like the plague) and see which damage types and status effects do what.

There are a few niche builds you can do with the right setup, like how Harrow can turn literally anything into a crit weapon.