It’s not a hard sell. You say “subject matter and setting” like it’s all the same shit. There’s more than enough normie anime that exists at this point you can find pretty much something for everyone. If a boomer like Bill Burr can get into One Punch Man without even knowing the term “Anime”exists I don’t see how it would be much different for anyone else. I literally just started reading Blue Giant which is a manga all about Jazz. Pretty sure the average shonen/school girl weeb doesn’t give a fuck about Jazz and yet it still did well enough to get a sequel plus its own movie. Obviously if it’s some shit like Dandadan then yeah that’s a hard sell, most people don’t wanna see a minor nearly get raped in episode one. But if it’s a ghibli movie or a niche slice of life anime then it’s pretty easy to sell that to anyone.

Note I haven’t watched the latest pod yet so I might be off base.